HK1041219B - Mucosal delivery system - Google Patents

Mucosal delivery system Download PDF

Info

Publication number
HK1041219B
HK1041219B HK02102996.8A HK02102996A HK1041219B HK 1041219 B HK1041219 B HK 1041219B HK 02102996 A HK02102996 A HK 02102996A HK 1041219 B HK1041219 B HK 1041219B
Authority
HK
Hong Kong
Prior art keywords
aluminium
mucosal membrane
hydroxide
mucosal
sulphate
Prior art date
Application number
HK02102996.8A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1041219A1 (en
Inventor
汉斯‧亨利克‧伊普森
漢斯‧亨利克‧伊普森
詹恩‧尤耳达尔拉贝克
詹恩‧尤耳達爾拉貝克
Original Assignee
爱尔开-阿贝优公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 爱尔开-阿贝优公司 filed Critical 爱尔开-阿贝优公司
Publication of HK1041219A1 publication Critical patent/HK1041219A1/en
Publication of HK1041219B publication Critical patent/HK1041219B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Vending Machines For Individual Products (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK02102996.8A 1999-02-05 2000-02-04 Mucosal delivery system HK1041219B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11889699P 1999-02-05 1999-02-05
DKPA199900155 1999-02-05
DK11599 1999-02-05
US60/118,896 1999-02-05
PCT/DK2000/000049 WO2000045847A1 (en) 1999-02-05 2000-02-04 Novel mucosal delivery system

Publications (2)

Publication Number Publication Date
HK1041219A1 HK1041219A1 (en) 2002-07-05
HK1041219B true HK1041219B (en) 2011-10-21

Family

ID=26063341

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102996.8A HK1041219B (en) 1999-02-05 2000-02-04 Mucosal delivery system

Country Status (10)

Country Link
EP (1) EP1146906B1 (enExample)
JP (1) JP2003517452A (enExample)
CN (1) CN1338947B (enExample)
AT (1) ATE515258T1 (enExample)
AU (1) AU771552B2 (enExample)
CA (1) CA2361377C (enExample)
DK (1) DK1146906T3 (enExample)
ES (1) ES2368987T3 (enExample)
HK (1) HK1041219B (enExample)
WO (1) WO2000045847A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020051794A1 (en) 2000-08-09 2002-05-02 Alk-Abello A/S Novel parenteral vaccine formulations and uses thereof
DE60139404D1 (de) * 2000-08-09 2009-09-10 Alk Abello As Parenterale impfstoff-formulierungen und deren verwendung
AU2004203772B2 (en) * 2003-01-07 2009-07-16 Yeda Research And Development Co. Ltd. Eye-drop vaccine containing copolymer 1 for therapeutic immunization
US20060115499A1 (en) * 2004-09-27 2006-06-01 Alk-Abello A/S Liquid allergy vaccine formulation for oromucosal administration
JP5628473B2 (ja) * 2004-11-10 2014-11-19 アルク−アベッロ エイ／エスＡｌｋ−Ａｂｅｌｌｏ Ａ／Ｓ アレルギーワクチンの粘膜投与によるアレルギーの予防治療方法
AU2006299310A1 (en) * 2005-10-04 2007-04-12 Alk-Abello A/S Solid vaccine formulation
BRPI0618241A2 (pt) * 2005-11-04 2011-08-23 Alk Abello As uso de um alérgeno para fabricação de uma formulação de vacina lìquida para prevenção ou tratamento de alergia
EP1814516B1 (en) * 2005-11-04 2012-12-26 Alk-Abelló A/S Use of a liquid allergy vaccine formulation for oromucosal administration
WO2009142772A2 (en) * 2008-05-23 2009-11-26 Mastcell Pharmaceuticals, Inc. Methods and treatment for allergies and inflammation associated with gastrointestinal diseases
CN102441162B (zh) * 2010-10-04 2018-07-24 免疫产品美国股份有限公司 结核病的治疗和预防
EP3556398A1 (en) * 2018-04-16 2019-10-23 Croda Denmark A/S Phytates for use as a biomolecules delivery or adsorption system
MX2021014936A (es) * 2019-06-11 2022-01-24 Glaxosmithkline Biologicals Sa Formulaciones de vacunas a traves de la mucosa.
CN111658611B (zh) * 2020-04-13 2021-06-01 四川大学 一种基于微乳的疫苗递送系统及其制备方法和应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3329564A (en) 1965-06-28 1967-07-04 Parke Davis & Co Antacid preparations and means of producing the same
DE2126957B2 (de) 1971-05-29 1977-07-07 Schettler, Hermann, Dr, East Lan sing, Mich (VStA) Verfahren zur herstellung von impfstoffen gegen gaensehepatitis
US4233288A (en) * 1979-03-12 1980-11-11 Cornell John A Gum emulsified liquid package for delivering and preserving liquid content in the mouth
JPS61238728A (ja) 1985-04-16 1986-10-24 Mitsui Norin Kk 茶葉抽出物と活性水酸化アルミニウムとの抗潰瘍性複合体
IL84167A (en) 1986-10-24 1991-04-15 Southern Res Inst Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation
JPH02124832A (ja) * 1988-07-08 1990-05-14 Toray Ind Inc インターヘェロンβ組成物
US5443832A (en) * 1990-04-16 1995-08-22 Institut Swisse De Recherches Experimentales Sur Le Cancer Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response
JP3132863B2 (ja) * 1991-10-24 2001-02-05 富山化学工業株式会社 徐放性口腔用軟膏
US5360792A (en) 1991-12-20 1994-11-01 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom
US5972336A (en) * 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
AU6414994A (en) 1993-03-18 1994-10-11 Cytimmune Sciences, Inc. Composition and method for reducing toxicity of biologically-active factors
GB9316745D0 (en) 1993-08-12 1993-09-29 Medeva Holdings Bv Vaccine compositions
JP3414539B2 (ja) * 1994-05-11 2003-06-09 有限会社ドット 経鼻吸収用組成物
JP2001515457A (ja) * 1995-06-07 2001-09-18 アルカームズ コントロールド セラピューティックス，インコーポレイテッド 凝集安定化生理活性物質放出用装置
US6221365B1 (en) * 1996-07-26 2001-04-24 American Cyanamid Company NucA protein of Haemophilus influenzae
WO1998040100A1 (en) * 1997-03-10 1998-09-17 Ottawa Civic Loeb Research Institute USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE AS AN ADJUVANT
DE69822542T2 (de) * 1997-04-23 2004-08-05 Pfizer Inc. Verkapslung einer Untereinheit des Bovinen Herpes Virus Typ-1 in wässrigen Lösungsmitteln als Impfstoff.
JPH11216357A (ja) * 1998-02-03 1999-08-10 Tsutsumi Techno Planning Kk 生理活性物質用の吸着担体
JPH11286438A (ja) * 1998-03-31 1999-10-19 Shiseido Co Ltd 徐放性製剤
JPH11302184A (ja) * 1998-04-21 1999-11-02 Taisho Pharmaceut Co Ltd 点鼻用組成物
JPH11322582A (ja) * 1998-05-06 1999-11-24 Dot:Kk 経鼻吸収用鼻粘膜付着・滞留型キャリヤ

Also Published As

Publication number Publication date
ATE515258T1 (de) 2011-07-15
WO2000045847A8 (en) 2010-12-02
EP1146906A1 (en) 2001-10-24
JP2003517452A (ja) 2003-05-27
EP1146906B1 (en) 2011-07-06
AU771552B2 (en) 2004-03-25
HK1041219A1 (en) 2002-07-05
CA2361377A1 (en) 2000-08-10
WO2000045847A1 (en) 2000-08-10
CN1338947A (zh) 2002-03-06
DK1146906T3 (da) 2011-10-24
CN1338947B (zh) 2012-11-14
AU2279700A (en) 2000-08-25
ES2368987T3 (es) 2011-11-24
CA2361377C (en) 2009-02-03

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150204