HK1035540A1 - N-acyl derivatives of the ll-e33288 antitumor antibiotics ll-e33288. - Google Patents

N-acyl derivatives of the ll-e33288 antitumor antibiotics ll-e33288.

Info

Publication number
HK1035540A1
HK1035540A1 HK01105824A HK01105824A HK1035540A1 HK 1035540 A1 HK1035540 A1 HK 1035540A1 HK 01105824 A HK01105824 A HK 01105824A HK 01105824 A HK01105824 A HK 01105824A HK 1035540 A1 HK1035540 A1 HK 1035540A1
Authority
HK
Hong Kong
Prior art keywords
acyl derivatives
antitumor antibiotics
acyl
antitumor
antibiotics
Prior art date
Application number
HK01105824A
Other languages
English (en)
Inventor
May Dean-Ming Lee
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of HK1035540A1 publication Critical patent/HK1035540A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29Micromonospora

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK01105824A 1989-04-14 1998-11-24 N-acyl derivatives of the ll-e33288 antitumor antibiotics ll-e33288. HK1035540A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/338,928 US5079233A (en) 1987-01-30 1989-04-14 N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same
HK98112287A HK1011368A1 (en) 1989-04-14 1998-11-24 N-acyl derivatives of the ll-e33288 antitumor antibiotics ll-e33288

Publications (1)

Publication Number Publication Date
HK1035540A1 true HK1035540A1 (en) 2001-11-30

Family

ID=23326735

Family Applications (2)

Application Number Title Priority Date Filing Date
HK01105824A HK1035540A1 (en) 1989-04-14 1998-11-24 N-acyl derivatives of the ll-e33288 antitumor antibiotics ll-e33288.
HK98112287A HK1011368A1 (en) 1989-04-14 1998-11-24 N-acyl derivatives of the ll-e33288 antitumor antibiotics ll-e33288

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK98112287A HK1011368A1 (en) 1989-04-14 1998-11-24 N-acyl derivatives of the ll-e33288 antitumor antibiotics ll-e33288

Country Status (23)

Country Link
US (1) US5079233A (fi)
EP (2) EP0392376B1 (fi)
JP (1) JP3083309B2 (fi)
KR (1) KR0149493B1 (fi)
CN (1) CN1027267C (fi)
AT (2) ATE297405T1 (fi)
AU (1) AU627863B2 (fi)
CA (1) CA2014472C (fi)
CZ (2) CZ284618B6 (fi)
DE (2) DE69033839T2 (fi)
DK (2) DK0392376T3 (fi)
ES (2) ES2240000T3 (fi)
FI (1) FI97889C (fi)
HK (2) HK1035540A1 (fi)
IE (1) IE20011013A1 (fi)
IL (1) IL93732A (fi)
NO (1) NO172938C (fi)
NZ (1) NZ233149A (fi)
PH (1) PH27361A (fi)
PT (1) PT93715B (fi)
SG (1) SG47857A1 (fi)
SK (1) SK188390A3 (fi)
ZA (1) ZA902839B (fi)

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JPS5644076B2 (fi) * 1973-07-12 1981-10-16
ES2177518T3 (es) * 1987-01-30 2002-12-16 American Cyanamid Co Derivados dihidro de los antibioticos ll-e33288.
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
EP0313873B1 (en) * 1987-10-30 1994-09-28 American Cyanamid Company Targeted forms of methyltrithio antitumor agents
IL93733A (en) * 1989-04-14 1996-01-19 American Cyanamid Co History of Dissolved Drug Sulphides Antibacterial and Antibacterial, Prepared from Compounds Containing Methyl-Thriteo Groups and Their Target Form

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KR0149493B1 (ko) 1998-08-17
ATE207926T1 (de) 2001-11-15
ES2240000T3 (es) 2005-10-16
ES2162783T3 (es) 2002-01-16
US5079233A (en) 1992-01-07
CZ53598A3 (cs) 1998-09-16
SG47857A1 (en) 1998-04-17
EP0392376A2 (en) 1990-10-17
SK281179B6 (sk) 2000-12-11
CA2014472C (en) 2000-03-28
FI97889B (fi) 1996-11-29
IL93732A (en) 1994-11-28
NO172938B (no) 1993-06-21
IE20011013A1 (en) 2002-12-30
PH27361A (en) 1993-06-21
PT93715A (pt) 1990-11-20
CN1048390A (zh) 1991-01-09
SK188390A3 (en) 2000-12-11
DK0392376T3 (da) 2001-12-03
NZ233149A (en) 1996-02-27
PT93715B (pt) 1996-08-30
ZA902839B (en) 1991-12-24
CZ188390A3 (cs) 1998-10-14
FI97889C (fi) 1997-03-10
NO172938C (no) 1993-12-29
CN1027267C (zh) 1995-01-04
IL93732A0 (en) 1990-12-23
ATE297405T1 (de) 2005-06-15
CZ284618B6 (cs) 1999-01-13
KR900016242A (ko) 1990-11-13
NO901654D0 (no) 1990-04-11
JP3083309B2 (ja) 2000-09-04
FI901865A0 (fi) 1990-05-12
EP0392376B1 (en) 2001-10-31
DE69034194T2 (de) 2005-11-03
EP1097937A1 (en) 2001-05-09
DE69033839T2 (de) 2002-06-06
DE69034194D1 (de) 2005-07-14
AU5324890A (en) 1990-10-18
CA2014472A1 (en) 1990-10-14
DK1097937T3 (da) 2005-09-19
JPH032192A (ja) 1991-01-08
NO901654L (no) 1990-10-15
CZ297668B6 (cs) 2007-02-28
EP1097937B1 (en) 2005-06-08
DE69033839D1 (de) 2001-12-06
AU627863B2 (en) 1992-09-03
HK1011368A1 (en) 1999-07-09
EP0392376A3 (en) 1991-08-14

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