HK1033171A1 - Process for obtaining l-dihydroorotic acid and usethereof - Google Patents

Process for obtaining l-dihydroorotic acid and usethereof

Info

Publication number
HK1033171A1
HK1033171A1 HK01103785A HK01103785A HK1033171A1 HK 1033171 A1 HK1033171 A1 HK 1033171A1 HK 01103785 A HK01103785 A HK 01103785A HK 01103785 A HK01103785 A HK 01103785A HK 1033171 A1 HK1033171 A1 HK 1033171A1
Authority
HK
Hong Kong
Prior art keywords
usethereof
obtaining
dihydroorotic acid
dihydroorotic
acid
Prior art date
Application number
HK01103785A
Other languages
English (en)
Inventor
Ulrike Milbert
Robert Bartlett
Eric Ruuth
Claude Fudali
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of HK1033171A1 publication Critical patent/HK1033171A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20Anion exchangers for chromatographic processes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/32Control of physical parameters of the fluid carrier of pressure or speed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
HK01103785A 1997-12-11 2001-06-01 Process for obtaining l-dihydroorotic acid and usethereof HK1033171A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97121848A EP0933633A1 (en) 1997-12-11 1997-12-11 Process for obtaining L-dihydroorotic acid and use thereof
PCT/EP1998/007972 WO1999030146A1 (en) 1997-12-11 1998-12-08 Process for obtaining l-dihydroorotic acid and use thereof

Publications (1)

Publication Number Publication Date
HK1033171A1 true HK1033171A1 (en) 2001-08-17

Family

ID=8227782

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01103785A HK1033171A1 (en) 1997-12-11 2001-06-01 Process for obtaining l-dihydroorotic acid and usethereof

Country Status (21)

Country Link
US (1) US6545006B1 (ko)
EP (2) EP0933633A1 (ko)
JP (1) JP4189124B2 (ko)
KR (1) KR100700906B1 (ko)
CN (1) CN1237345C (ko)
AR (1) AR016430A1 (ko)
AT (1) ATE305610T1 (ko)
AU (1) AU747993B2 (ko)
BR (1) BR9813559A (ko)
CA (1) CA2315326A1 (ko)
CZ (1) CZ299968B6 (ko)
DE (1) DE69831752T2 (ko)
DK (1) DK1036319T3 (ko)
ES (1) ES2248927T3 (ko)
HK (1) HK1033171A1 (ko)
HU (1) HUP0004510A3 (ko)
ID (1) ID24807A (ko)
PL (1) PL194068B1 (ko)
RU (1) RU2228932C2 (ko)
TR (1) TR200001671T2 (ko)
WO (1) WO1999030146A1 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU779931B2 (en) * 1999-12-16 2005-02-17 Teva Pharmaceutical Industries Ltd. Novel processes for making- and a new crystalline form of- leflunomide
WO2013180140A1 (ja) * 2012-05-29 2013-12-05 エヌエーアイ株式会社 ジヒドロオロト酸脱水素酵素阻害剤
US10708575B2 (en) 2012-06-25 2020-07-07 Sharp Kabushiki Kaisha Display system with diffuse and specular reflective modes
US9679506B2 (en) 2012-06-25 2017-06-13 Sharp Kabushiki Kaisha Multiple function display system
CN102787147B (zh) * 2012-08-31 2014-10-08 南京工业大学 一种酶法制备l-二氢乳清酸的方法
US10699612B2 (en) 2014-10-27 2020-06-30 Sharp Kabushiki Kaisha Display system with specular reflective mode
CN112305097A (zh) * 2020-09-30 2021-02-02 辰欣药业股份有限公司 一种特立氟胺片有关物质的检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2773872A (en) * 1954-04-12 1956-12-11 Merck & Co Inc Dihydroorotic acid
HU178201B (en) * 1977-08-05 1982-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing substituted orto-acids and dihydro-orto-acids and derivatives thereof
DE19539638A1 (de) * 1995-10-25 1997-04-30 Hoechst Ag Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen

Also Published As

Publication number Publication date
EP1036319B1 (en) 2005-09-28
PL194068B1 (pl) 2007-04-30
CN1281550A (zh) 2001-01-24
ATE305610T1 (de) 2005-10-15
CZ20002134A3 (cs) 2000-10-11
HUP0004510A1 (hu) 2001-04-28
DE69831752D1 (de) 2006-02-09
JP4189124B2 (ja) 2008-12-03
CA2315326A1 (en) 1999-06-17
ES2248927T3 (es) 2006-03-16
AU747993B2 (en) 2002-05-30
RU2228932C2 (ru) 2004-05-20
AR016430A1 (es) 2001-07-04
HUP0004510A3 (en) 2003-05-28
US6545006B1 (en) 2003-04-08
DE69831752T2 (de) 2006-06-22
TR200001671T2 (tr) 2000-11-21
KR100700906B1 (ko) 2007-03-29
CZ299968B6 (cs) 2009-01-07
WO1999030146A1 (en) 1999-06-17
JP2001526387A (ja) 2001-12-18
AU1877599A (en) 1999-06-28
CN1237345C (zh) 2006-01-18
EP0933633A1 (en) 1999-08-04
EP1036319A1 (en) 2000-09-20
PL341205A1 (en) 2001-03-26
DK1036319T3 (da) 2006-01-16
BR9813559A (pt) 2000-10-10
KR20010032978A (ko) 2001-04-25
ID24807A (id) 2000-08-24

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20091208