HK1027807A1 - Process for the synthesis of chloropurine intermediates - Google Patents

Process for the synthesis of chloropurine intermediates

Info

Publication number
HK1027807A1
HK1027807A1 HK00106983A HK00106983A HK1027807A1 HK 1027807 A1 HK1027807 A1 HK 1027807A1 HK 00106983 A HK00106983 A HK 00106983A HK 00106983 A HK00106983 A HK 00106983A HK 1027807 A1 HK1027807 A1 HK 1027807A1
Authority
HK
Hong Kong
Prior art keywords
synthesis
chloropurine
intermediates
chloropurine intermediates
Prior art date
Application number
HK00106983A
Other languages
English (en)
Inventor
Martin Francis Jones
Christopher John Wallis
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of HK1027807A1 publication Critical patent/HK1027807A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK00106983A 1997-10-14 2000-11-02 Process for the synthesis of chloropurine intermediates HK1027807A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9721780.6A GB9721780D0 (en) 1997-10-14 1997-10-14 Process for the synthesis of chloropurine intermediates
PCT/GB1998/003080 WO1999019327A1 (en) 1997-10-14 1998-10-14 Process for the synthesis of chloropurine intermediates

Publications (1)

Publication Number Publication Date
HK1027807A1 true HK1027807A1 (en) 2001-01-23

Family

ID=10820547

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00106983A HK1027807A1 (en) 1997-10-14 2000-11-02 Process for the synthesis of chloropurine intermediates

Country Status (44)

Country Link
US (1) US6646125B1 (tr)
EP (1) EP1023292B1 (tr)
JP (1) JP4531250B2 (tr)
KR (1) KR100543845B1 (tr)
CN (1) CN1160354C (tr)
AP (1) AP1182A (tr)
AR (1) AR014921A1 (tr)
AT (1) ATE249461T1 (tr)
AU (1) AU738462B2 (tr)
BG (1) BG64597B1 (tr)
BR (1) BR9813048B1 (tr)
CA (1) CA2306958C (tr)
CO (1) CO4980899A1 (tr)
CZ (1) CZ294482B6 (tr)
DE (1) DE69818084T2 (tr)
DK (1) DK1023292T3 (tr)
EA (1) EA003183B1 (tr)
EE (1) EE04059B1 (tr)
EG (1) EG21730A (tr)
ES (1) ES2205553T3 (tr)
GB (1) GB9721780D0 (tr)
GE (1) GEP20022679B (tr)
HK (1) HK1027807A1 (tr)
HR (1) HRP20000216B1 (tr)
HU (1) HUP0003984A3 (tr)
ID (1) ID24927A (tr)
IL (1) IL135323A (tr)
IN (1) IN184590B (tr)
IS (1) IS2195B (tr)
MA (1) MA24676A1 (tr)
MY (1) MY127470A (tr)
NO (1) NO325030B1 (tr)
NZ (1) NZ503679A (tr)
OA (1) OA11370A (tr)
PE (1) PE121899A1 (tr)
PL (1) PL188477B1 (tr)
PT (1) PT1023292E (tr)
RS (1) RS49710B (tr)
SK (1) SK285331B6 (tr)
TR (1) TR200000976T2 (tr)
TW (1) TW436488B (tr)
UA (1) UA54550C2 (tr)
WO (1) WO1999019327A1 (tr)
ZA (1) ZA989338B (tr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284596B6 (sk) 1997-11-27 2005-07-01 Lonza Ag Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purin-9-yl)-2-cyklopentén-1-metanolu alebo jeho solí
FR2849030A1 (fr) * 2002-12-20 2004-06-25 Isochem Sa Procede de preparation des n-(2-amino-4, 6-dihalogenopyrimidin-5-yl) formamides
GB0320738D0 (en) 2003-09-04 2003-10-08 Glaxo Group Ltd Novel process
CN100465174C (zh) * 2006-06-13 2009-03-04 中国科学院上海有机化学研究所 制备光学纯阿巴卡韦的方法
KR101109476B1 (ko) * 2009-06-26 2012-01-31 현대제철 주식회사 실린더 교체용 지그장치
ES2670811T3 (es) 2010-01-27 2018-06-01 Viiv Healthcare Company Terapia antivírica
CN104672239A (zh) * 2013-11-26 2015-06-03 上海迪赛诺化学制药有限公司 一种采用一锅法制备阿巴卡韦式v中间体的工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
JPS6175A (ja) * 1984-03-06 1986-01-06 ブリストル−マイア−ズ　コムパニ− 神経弛緩剤、１‐フルオロフェニルブチル‐４‐（５‐ハロ‐２‐ピリミジニル）ピペラジン誘導体
NZ227663A (en) 1988-01-20 1990-09-26 Univ Minnesota Purine nucleoside analogues, pyrimidine derivatives and pharmaceutical compositions
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5329008A (en) * 1993-04-07 1994-07-12 Glaxo Inc. Synthesis of a 3,4-dihydroxy-1-cyclopentanylpurinone
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
SK285228B6 (sk) * 1997-05-13 2006-09-07 Lonza Ag Spôsob výroby racemického alebo opticky aktívnehoderivátu 4-(hydroxymetyl)-2-cyklopenténu a racemicky N-butyryl-1-amino-4- (hydroxymetyl)-2-cyklopentén

Also Published As

Publication number Publication date
AP1182A (en) 2003-06-18
IN184590B (tr) 2000-09-09
HRP20000216B1 (en) 2002-08-31
HUP0003984A3 (en) 2002-12-28
SK5362000A3 (en) 2001-03-12
NO20001896L (no) 2000-06-13
TW436488B (en) 2001-05-28
PT1023292E (pt) 2004-02-27
CZ294482B6 (cs) 2005-01-12
AU738462B2 (en) 2001-09-20
NO20001896D0 (no) 2000-04-12
TR200000976T2 (tr) 2000-11-21
BG104352A (en) 2001-02-28
IL135323A0 (en) 2001-05-20
EE04059B1 (et) 2003-06-16
JP4531250B2 (ja) 2010-08-25
CN1160354C (zh) 2004-08-04
OA11370A (en) 2004-01-27
PL339904A1 (en) 2001-01-15
IL135323A (en) 2004-07-25
UA54550C2 (uk) 2003-03-17
GEP20022679B (en) 2002-04-25
IS5423A (is) 2000-03-28
JP2001519432A (ja) 2001-10-23
EP1023292A1 (en) 2000-08-02
CA2306958C (en) 2007-09-04
IS2195B (is) 2007-01-15
AR014921A1 (es) 2001-04-11
ID24927A (id) 2000-08-31
ZA989338B (en) 2000-04-13
PE121899A1 (es) 1999-12-20
CO4980899A1 (es) 2000-11-27
ES2205553T3 (es) 2004-05-01
ATE249461T1 (de) 2003-09-15
HRP20000216A2 (en) 2000-08-31
AP2000001790A0 (en) 2000-06-30
MY127470A (en) 2006-12-29
DK1023292T3 (da) 2003-11-10
EG21730A (en) 2002-02-27
KR100543845B1 (ko) 2006-01-23
NZ503679A (en) 2002-09-27
BR9813048A (pt) 2000-08-15
RS49710B (sr) 2007-12-31
EA003183B1 (ru) 2003-02-27
PL188477B1 (pl) 2005-02-28
SK285331B6 (sk) 2006-11-03
KR20010015744A (ko) 2001-02-26
CN1281457A (zh) 2001-01-24
BR9813048B1 (pt) 2010-07-13
YU20200A (sh) 2003-02-28
DE69818084T2 (de) 2004-07-15
EA200000318A1 (ru) 2000-12-25
DE69818084D1 (de) 2003-10-16
GB9721780D0 (en) 1997-12-10
NO325030B1 (no) 2008-01-21
MA24676A1 (fr) 1999-07-01
HUP0003984A2 (hu) 2001-04-28
WO1999019327A1 (en) 1999-04-22
US6646125B1 (en) 2003-11-11
CZ20001367A3 (cs) 2000-10-11
EE200000162A (et) 2001-04-16
EP1023292B1 (en) 2003-09-10
CA2306958A1 (en) 1999-04-22
BG64597B1 (bg) 2005-08-31
AU9547698A (en) 1999-05-03

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20181013