HK1023501A1 - Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases - Google Patents

Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases

Info

Publication number
HK1023501A1
HK1023501A1 HK00102322.5A HK00102322A HK1023501A1 HK 1023501 A1 HK1023501 A1 HK 1023501A1 HK 00102322 A HK00102322 A HK 00102322A HK 1023501 A1 HK1023501 A1 HK 1023501A1
Authority
HK
Hong Kong
Prior art keywords
inhibitor
treating
combination therapy
mediated diseases
methotrexate
Prior art date
Application number
HK00102322.5A
Other languages
English (en)
Inventor
Alison M Bendele
Regina M Sennello
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of HK1023501A1 publication Critical patent/HK1023501A1/xx

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
HK00102322.5A 1996-12-06 2000-04-18 Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases HK1023501A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3279096P 1996-12-06 1996-12-06
US3635397P 1997-01-23 1997-01-23
US3931197P 1997-02-07 1997-02-07
US5202597P 1997-07-09 1997-07-09
PCT/US1997/022720 WO1998024477A1 (fr) 1996-12-06 1997-12-08 Therapie combinee utilisant un inhibiteur de l'il-1 pour traiter les maladies induites par l'il-1

Publications (1)

Publication Number Publication Date
HK1023501A1 true HK1023501A1 (en) 2000-09-15

Family

ID=27488035

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00102322.5A HK1023501A1 (en) 1996-12-06 2000-04-18 Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases

Country Status (10)

Country Link
US (3) US20030072756A1 (fr)
EP (2) EP2002846B1 (fr)
JP (3) JP4771563B2 (fr)
AT (1) ATE406176T1 (fr)
AU (1) AU736876B2 (fr)
CA (1) CA2273852C (fr)
DE (1) DE69738948D1 (fr)
ES (2) ES2312179T3 (fr)
HK (1) HK1023501A1 (fr)
WO (1) WO1998024477A1 (fr)

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CA2273852A1 (fr) 1998-06-11
JP2009007380A (ja) 2009-01-15
AU736876B2 (en) 2001-08-02
DE69738948D1 (de) 2008-10-09
EP2002846A3 (fr) 2009-01-14
AU5795598A (en) 1998-06-29
WO1998024477A1 (fr) 1998-06-11
EP2002846B1 (fr) 2017-01-25
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ATE406176T1 (de) 2008-09-15
US20030072756A1 (en) 2003-04-17
ES2615357T3 (es) 2017-06-06
EP0949931A1 (fr) 1999-10-20
JP2006306890A (ja) 2006-11-09
US20090203609A1 (en) 2009-08-13
US20040044001A1 (en) 2004-03-04
CA2273852C (fr) 2009-09-29
ES2312179T3 (es) 2009-02-16

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