DK590387A - Antistoffer mod interleukin-1 - Google Patents
Antistoffer mod interleukin-1Info
- Publication number
- DK590387A DK590387A DK590387A DK590387A DK590387A DK 590387 A DK590387 A DK 590387A DK 590387 A DK590387 A DK 590387A DK 590387 A DK590387 A DK 590387A DK 590387 A DK590387 A DK 590387A
- Authority
- DK
- Denmark
- Prior art keywords
- antibodies against
- against interleukin
- interleukin
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27099286 | 1986-11-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK590387D0 DK590387D0 (da) | 1987-11-11 |
DK590387A true DK590387A (da) | 1988-05-14 |
Family
ID=17493888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK590387A DK590387A (da) | 1986-11-13 | 1987-11-11 | Antistoffer mod interleukin-1 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0267611B1 (da) |
KR (1) | KR900004420B1 (da) |
DE (1) | DE3785994T2 (da) |
DK (1) | DK590387A (da) |
ES (1) | ES2054644T3 (da) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5998578A (en) * | 1984-05-18 | 1999-12-07 | New England Medical Center Hospitals, Inc. | Biologically active fragments of IL-1β |
EP0569687B1 (en) * | 1984-05-18 | 2002-08-21 | New England Medical Center Hospitals, Inc. | Human IL-1 cDNA sequences encoding biologically-active human IL-1 proteins |
EP0364778B1 (en) * | 1988-10-01 | 1996-03-13 | Otsuka Pharmaceutical Co., Ltd. | Antibody against interleukin-1beta |
JPH0681599B2 (ja) * | 1988-10-01 | 1994-10-19 | 大塚製薬株式会社 | インターロイキン―1βに対する抗体 |
FR2640146B1 (fr) * | 1988-12-08 | 1993-12-24 | Commissariat A Energie Atomique | Anticorps monoclonaux anti-interleukines 1(alpha) et 1(beta), leur procede de production et applications desdits anticorps a la detection des interleukines 1(alpha) et 1(beta) et en therapeutique |
DK195089A (da) * | 1989-04-20 | 1990-10-21 | Morten Bagge Hansen | Regulatoriske proteiner |
JPH05503098A (ja) * | 1989-12-15 | 1993-05-27 | カイロン コーポレイション | セプシスの処理のためのサイトカイン抗体 |
WO1995001997A1 (en) * | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
EP0659766A1 (en) * | 1993-11-23 | 1995-06-28 | Schering-Plough | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
US5959085A (en) * | 1993-11-23 | 1999-09-28 | Schering Corporation | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
DE4408890A1 (de) * | 1994-03-16 | 1995-09-21 | Knoll Ag | Verwendung von Il-1-Antagonisten als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel |
DK0813423T3 (da) * | 1995-01-23 | 2002-07-22 | Xenotech Inc | Præparat til forebyggelse af osteolysis og metastase |
CA2255906A1 (en) * | 1996-05-20 | 1997-11-27 | Schering Corporation | Human interleukin-1j and antagonists thereof |
CA2273852C (en) | 1996-12-06 | 2009-09-29 | Amgen Inc. | Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases |
US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
GB0020685D0 (en) | 2000-08-22 | 2000-10-11 | Novartis Ag | Organic compounds |
ES2674888T3 (es) | 2001-06-26 | 2018-07-04 | Amgen Inc. | Anticuerpos para OPGL |
EP2213685B1 (en) | 2002-09-06 | 2013-11-27 | Amgen Inc. | Therapeutic anti-IL-1R1 monoclonal antibody |
JP2006517191A (ja) | 2002-12-30 | 2006-07-20 | アムジエン・インコーポレーテツド | 共刺激因子を用いた併用療法 |
EP1851245B1 (en) | 2005-01-26 | 2012-10-10 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
MX2007016032A (es) | 2005-06-21 | 2008-03-10 | Xoma Technology Ltd | Anticuerpos de enlace a il-1-beta y fragmentos de los mismos. |
EP2216653A1 (en) | 2005-08-02 | 2010-08-11 | XBiotech, Inc | Diagnosis, treatment and prevention of vascular disorders using il-1alpha autoantibodies |
PE20070684A1 (es) | 2005-11-14 | 2007-08-06 | Amgen Inc | MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP |
EP3124045A3 (en) | 2006-12-20 | 2017-05-03 | Xoma (Us) Llc | Treatment of il-1 beta related diseases |
PL2391650T3 (pl) | 2007-12-20 | 2015-03-31 | Xoma Us Llc | Sposoby leczenia dny |
KR20150127300A (ko) | 2008-05-30 | 2015-11-16 | 엑스바이오테크, 인크. | 인터류킨-1 알파 항체 및 그의 사용 방법 |
CA2735939A1 (en) | 2008-09-05 | 2010-03-11 | Xoma Technology Ltd. | Methods for improvement of beta cell function |
US8242074B2 (en) | 2008-09-12 | 2012-08-14 | Xbiotech, Inc. | Modulation of the amount or function of pathogenic CD14+CD16+ monocytes |
BR112012028557A2 (pt) | 2010-05-07 | 2019-09-24 | Xoma Technology Ltd. | uso de um anticorpo anti-il-1b ou de fragmentos de ligação do mesmo. |
WO2011159976A2 (en) | 2010-06-18 | 2011-12-22 | Xbiotech, Inc. | Arthritis treatment |
NZ607472A (en) | 2010-08-23 | 2014-09-26 | Xbiotech Inc | Treatment for neoplastic diseases |
US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
US9809649B2 (en) | 2011-09-23 | 2017-11-07 | Xbiotech, Inc. | Cachexia treatment |
CN104144946A (zh) | 2011-12-19 | 2014-11-12 | 爱克索马美国有限责任公司 | 治疗痤疮的方法 |
US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
JP7145162B2 (ja) | 2017-02-16 | 2022-09-30 | ヤンセン バイオテク,インコーポレイテッド | 化膿性汗腺炎の処置 |
US20210236599A1 (en) | 2018-08-13 | 2021-08-05 | Iltoo Pharma | Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK172052B1 (da) * | 1984-12-21 | 1997-09-29 | Otsuka Pharma Co Ltd | Antitumor-aktivt stof, fremgangsmåde til dets fremstilling, lægemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme transformet med en sådan vektor |
DE3587605T2 (de) * | 1984-12-25 | 1994-03-17 | Dainippon Pharmaceutical Co | Interleukin-1 und dessen Derivat. |
JPS6291197A (ja) * | 1985-10-17 | 1987-04-25 | Dainippon Pharmaceut Co Ltd | 抗ヒトインタ−ロイキン1抗体,その製法及びその使用法 |
-
1987
- 1987-11-11 DK DK590387A patent/DK590387A/da not_active Application Discontinuation
- 1987-11-12 ES ES87116724T patent/ES2054644T3/es not_active Expired - Lifetime
- 1987-11-12 EP EP87116724A patent/EP0267611B1/en not_active Expired - Lifetime
- 1987-11-12 DE DE87116724T patent/DE3785994T2/de not_active Expired - Fee Related
- 1987-11-13 KR KR1019870012791A patent/KR900004420B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR880006357A (ko) | 1988-07-22 |
DK590387D0 (da) | 1987-11-11 |
ES2054644T3 (es) | 1994-08-16 |
EP0267611B1 (en) | 1993-05-26 |
EP0267611A3 (en) | 1988-09-21 |
KR900004420B1 (ko) | 1990-06-25 |
DE3785994T2 (de) | 1993-11-11 |
EP0267611A2 (en) | 1988-05-18 |
DE3785994D1 (de) | 1993-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |