DK590387A - Antistoffer mod interleukin-1 - Google Patents

Antistoffer mod interleukin-1

Info

Publication number
DK590387A
DK590387A DK590387A DK590387A DK590387A DK 590387 A DK590387 A DK 590387A DK 590387 A DK590387 A DK 590387A DK 590387 A DK590387 A DK 590387A DK 590387 A DK590387 A DK 590387A
Authority
DK
Denmark
Prior art keywords
antibodies against
against interleukin
interleukin
antibodies
Prior art date
Application number
DK590387A
Other languages
English (en)
Other versions
DK590387D0 (da
Inventor
Yasukazu Ohmoto
Kenji Nagamura
Hisakazu Aoki
Yoshikatsu Hirai
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of DK590387D0 publication Critical patent/DK590387D0/da
Publication of DK590387A publication Critical patent/DK590387A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
DK590387A 1986-11-13 1987-11-11 Antistoffer mod interleukin-1 DK590387A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27099286 1986-11-13

Publications (2)

Publication Number Publication Date
DK590387D0 DK590387D0 (da) 1987-11-11
DK590387A true DK590387A (da) 1988-05-14

Family

ID=17493888

Family Applications (1)

Application Number Title Priority Date Filing Date
DK590387A DK590387A (da) 1986-11-13 1987-11-11 Antistoffer mod interleukin-1

Country Status (5)

Country Link
EP (1) EP0267611B1 (da)
KR (1) KR900004420B1 (da)
DE (1) DE3785994T2 (da)
DK (1) DK590387A (da)
ES (1) ES2054644T3 (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998578A (en) * 1984-05-18 1999-12-07 New England Medical Center Hospitals, Inc. Biologically active fragments of IL-1β
EP0569687B1 (en) * 1984-05-18 2002-08-21 New England Medical Center Hospitals, Inc. Human IL-1 cDNA sequences encoding biologically-active human IL-1 proteins
EP0364778B1 (en) * 1988-10-01 1996-03-13 Otsuka Pharmaceutical Co., Ltd. Antibody against interleukin-1beta
JPH0681599B2 (ja) * 1988-10-01 1994-10-19 大塚製薬株式会社 インターロイキン―１βに対する抗体
FR2640146B1 (fr) * 1988-12-08 1993-12-24 Commissariat A Energie Atomique Anticorps monoclonaux anti-interleukines 1(alpha) et 1(beta), leur procede de production et applications desdits anticorps a la detection des interleukines 1(alpha) et 1(beta) et en therapeutique
DK195089A (da) * 1989-04-20 1990-10-21 Morten Bagge Hansen Regulatoriske proteiner
JPH05503098A (ja) * 1989-12-15 1993-05-27 カイロン　コーポレイション セプシスの処理のためのサイトカイン抗体
WO1995001997A1 (en) * 1993-07-09 1995-01-19 Smithkline Beecham Corporation RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN
EP0659766A1 (en) * 1993-11-23 1995-06-28 Schering-Plough Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
US5959085A (en) * 1993-11-23 1999-09-28 Schering Corporation Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
DE4408890A1 (de) * 1994-03-16 1995-09-21 Knoll Ag Verwendung von Il-1-Antagonisten als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel
DK0813423T3 (da) * 1995-01-23 2002-07-22 Xenotech Inc Præparat til forebyggelse af osteolysis og metastase
CA2255906A1 (en) * 1996-05-20 1997-11-27 Schering Corporation Human interleukin-1j and antagonists thereof
CA2273852C (en) 1996-12-06 2009-09-29 Amgen Inc. Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
GB0020685D0 (en) 2000-08-22 2000-10-11 Novartis Ag Organic compounds
ES2674888T3 (es) 2001-06-26 2018-07-04 Amgen Inc. Anticuerpos para OPGL
EP2213685B1 (en) 2002-09-06 2013-11-27 Amgen Inc. Therapeutic anti-IL-1R1 monoclonal antibody
JP2006517191A (ja) 2002-12-30 2006-07-20 アムジエン・インコーポレーテツド 共刺激因子を用いた併用療法
EP1851245B1 (en) 2005-01-26 2012-10-10 Amgen Fremont Inc. Antibodies against interleukin-1 beta
MX2007016032A (es) 2005-06-21 2008-03-10 Xoma Technology Ltd Anticuerpos de enlace a il-1-beta y fragmentos de los mismos.
EP2216653A1 (en) 2005-08-02 2010-08-11 XBiotech, Inc Diagnosis, treatment and prevention of vascular disorders using il-1alpha autoantibodies
PE20070684A1 (es) 2005-11-14 2007-08-06 Amgen Inc MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
EP3124045A3 (en) 2006-12-20 2017-05-03 Xoma (Us) Llc Treatment of il-1 beta related diseases
PL2391650T3 (pl) 2007-12-20 2015-03-31 Xoma Us Llc Sposoby leczenia dny
KR20150127300A (ko) 2008-05-30 2015-11-16 엑스바이오테크, 인크. 인터류킨-1 알파 항체 및 그의 사용 방법
CA2735939A1 (en) 2008-09-05 2010-03-11 Xoma Technology Ltd. Methods for improvement of beta cell function
US8242074B2 (en) 2008-09-12 2012-08-14 Xbiotech, Inc. Modulation of the amount or function of pathogenic CD14+CD16+ monocytes
BR112012028557A2 (pt) 2010-05-07 2019-09-24 Xoma Technology Ltd. uso de um anticorpo anti-il-1b ou de fragmentos de ligação do mesmo.
WO2011159976A2 (en) 2010-06-18 2011-12-22 Xbiotech, Inc. Arthritis treatment
NZ607472A (en) 2010-08-23 2014-09-26 Xbiotech Inc Treatment for neoplastic diseases
US9724409B2 (en) 2011-04-01 2017-08-08 Xbiotech, Inc. Treatment of inflammatory skin disease
US9809649B2 (en) 2011-09-23 2017-11-07 Xbiotech, Inc. Cachexia treatment
CN104144946A (zh) 2011-12-19 2014-11-12 爱克索马美国有限责任公司 治疗痤疮的方法
US9545441B2 (en) 2012-09-18 2017-01-17 Xbiotech, Inc. Treatment of diabetes
JP7145162B2 (ja) 2017-02-16 2022-09-30 ヤンセン バイオテク，インコーポレイテッド 化膿性汗腺炎の処置
US20210236599A1 (en) 2018-08-13 2021-08-05 Iltoo Pharma Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK172052B1 (da) * 1984-12-21 1997-09-29 Otsuka Pharma Co Ltd Antitumor-aktivt stof, fremgangsmåde til dets fremstilling, lægemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme transformet med en sådan vektor
DE3587605T2 (de) * 1984-12-25 1994-03-17 Dainippon Pharmaceutical Co Interleukin-1 und dessen Derivat.
JPS6291197A (ja) * 1985-10-17 1987-04-25 Dainippon Pharmaceut Co Ltd 抗ヒトインタ−ロイキン１抗体，その製法及びその使用法

Also Published As

Publication number Publication date
KR880006357A (ko) 1988-07-22
DK590387D0 (da) 1987-11-11
ES2054644T3 (es) 1994-08-16
EP0267611B1 (en) 1993-05-26
EP0267611A3 (en) 1988-09-21
KR900004420B1 (ko) 1990-06-25
DE3785994T2 (de) 1993-11-11
EP0267611A2 (en) 1988-05-18
DE3785994D1 (de) 1993-07-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment