HK1019405A1 - Antithrombotic and antiatherogenic pharmaceutical composition including a thienopyridine derivative and an hmg-coareductase inhibitor - Google Patents

Antithrombotic and antiatherogenic pharmaceutical composition including a thienopyridine derivative and an hmg-coareductase inhibitor

Info

Publication number
HK1019405A1
HK1019405A1 HK99104578A HK99104578A HK1019405A1 HK 1019405 A1 HK1019405 A1 HK 1019405A1 HK 99104578 A HK99104578 A HK 99104578A HK 99104578 A HK99104578 A HK 99104578A HK 1019405 A1 HK1019405 A1 HK 1019405A1
Authority
HK
Hong Kong
Prior art keywords
antithrombotic
hmg
pharmaceutical composition
composition including
thienopyridine derivative
Prior art date
Application number
HK99104578A
Other languages
English (en)
Inventor
Georges Daste
Jean-Marc Herbert
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of HK1019405A1 publication Critical patent/HK1019405A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K41/00—Spindle sealings
    • F16K41/02—Spindle sealings with stuffing-box ; Sealing rings
    • F16K41/04—Spindle sealings with stuffing-box ; Sealing rings with at least one ring of rubber or like material between spindle and housing
    • F16K41/043—Spindle sealings with stuffing-box ; Sealing rings with at least one ring of rubber or like material between spindle and housing for spindles which only rotate, i.e. non-rising spindles
    • F16K41/046—Spindle sealings with stuffing-box ; Sealing rings with at least one ring of rubber or like material between spindle and housing for spindles which only rotate, i.e. non-rising spindles for rotating valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02D—CONTROLLING COMBUSTION ENGINES
    • F02D9/00—Controlling engines by throttling air or fuel-and-air induction conduits or exhaust conduits
    • F02D9/04—Controlling engines by throttling air or fuel-and-air induction conduits or exhaust conduits concerning exhaust conduits
    • F02D9/06—Exhaust brakes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K1/00—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces
    • F16K1/16—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members
    • F16K1/18—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members with pivoted discs or flaps
    • F16K1/22—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members with pivoted discs or flaps with axis of rotation crossing the valve member, e.g. butterfly valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Combustion & Propulsion (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HK99104578A 1996-07-26 1999-11-01 Antithrombotic and antiatherogenic pharmaceutical composition including a thienopyridine derivative and an hmg-coareductase inhibitor HK1019405A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9609474A FR2751540B1 (fr) 1996-07-26 1996-07-26 Composition pharmaceutique antithrombotique
PCT/FR1997/001353 WO1998004259A1 (fr) 1996-07-26 1997-07-21 COMPOSITION PHARMACEUTIQUE ANTITHROMBOTIQUE ET ANTIATHEROGENE COMPRENANT UN DERIVE DE THIENOPYRIDINE ET UN INHIBITEUR DE LA HMG-CoA-REDUCTASE

Publications (1)

Publication Number Publication Date
HK1019405A1 true HK1019405A1 (en) 2000-02-11

Family

ID=9494551

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99104578A HK1019405A1 (en) 1996-07-26 1999-11-01 Antithrombotic and antiatherogenic pharmaceutical composition including a thienopyridine derivative and an hmg-coareductase inhibitor

Country Status (35)

Country Link
US (1) US6218403B1 (zh)
EP (1) EP0914124B1 (zh)
JP (1) JP3553610B2 (zh)
KR (1) KR100307268B1 (zh)
CN (1) CN1109547C (zh)
AR (1) AR008782A1 (zh)
AT (1) ATE258052T1 (zh)
AU (1) AU725949B2 (zh)
BR (1) BR9710560B1 (zh)
CA (1) CA2261099C (zh)
CZ (1) CZ294664B6 (zh)
DE (1) DE69727299T2 (zh)
DK (1) DK0914124T3 (zh)
EE (1) EE03853B1 (zh)
ES (1) ES2214632T3 (zh)
FR (1) FR2751540B1 (zh)
HK (1) HK1019405A1 (zh)
HU (1) HU226245B1 (zh)
ID (1) ID17774A (zh)
IL (1) IL128102A0 (zh)
IS (1) IS2052B (zh)
MY (1) MY125051A (zh)
NO (1) NO322894B1 (zh)
NZ (1) NZ333826A (zh)
PL (1) PL188739B1 (zh)
PT (1) PT914124E (zh)
RS (1) RS49504B (zh)
RU (1) RU2176504C2 (zh)
SI (1) SI0914124T1 (zh)
SK (1) SK284944B6 (zh)
TR (1) TR199900154T2 (zh)
TW (1) TW442289B (zh)
UA (1) UA58518C2 (zh)
WO (1) WO1998004259A1 (zh)
ZA (1) ZA976247B (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2769313B1 (fr) * 1997-10-06 2000-04-21 Sanofi Sa Derives d'esters hydroxyacetiques, leur procede de preparation et leur utilisation comme intermediaires de synthese
US7141602B2 (en) * 1998-09-18 2006-11-28 Lek Pharmaceuticals D.D. Process for obtaining HMG-CoA reductase inhibitors of high purity
IL162461A0 (en) * 2001-12-18 2005-11-20 Teva Pharma Polymorphs of clopidogrel hydrogensulfate
US7074928B2 (en) 2002-01-11 2006-07-11 Teva Pharmaceutical Industries, Ltd. Polymorphs of clopidogrel hydrogensulfate
AR040588A1 (es) * 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
IL166593A0 (en) 2002-08-02 2006-01-15 Racemization and enantiomer separation of clopidogrel
US6800759B2 (en) 2002-08-02 2004-10-05 Teva Pharmaceutical Industries Ltd. Racemization and enantiomer separation of clopidogrel
ATE482698T1 (de) * 2003-06-18 2010-10-15 Inst Cardiologie De Montreal M Vermeidung von vorhofflimmern (af) mit der verwendung von statin
US6978908B2 (en) * 2003-09-15 2005-12-27 Gerber Products Company Drinking vessel with adjustable handles
KR100563455B1 (ko) * 2004-04-09 2006-03-23 한미약품 주식회사 결정성 클로피도그렐 나프탈렌술폰산염 또는 이의 수화물,이의 제조방법 및 이를 함유하는 약학적 조성물
ES2378896T3 (es) * 2005-09-15 2012-04-18 Otsuka Pharmaceutical Co., Ltd. Combinación de fármacos que contiene Probucol y un derivado de tetrazolilalcoxi-dihidrocarbostirilo con efectos inhibidores del superóxido
US9532945B2 (en) * 2006-04-04 2017-01-03 Kg Acquisition Llc Oral dosage forms including an antiplatelet agent and an enterically coated acid inhibitor
CN101460154B (zh) * 2006-04-04 2015-07-01 Kg艾克维泽生公司 包含抗血小板剂和抑酸剂的口服剂型
WO2008019053A2 (en) * 2006-08-03 2008-02-14 Teva Pharmaceutical Industries Ltd. Process for preparing clopidogrel bisulphate
WO2008060934A2 (en) * 2006-11-14 2008-05-22 Acusphere, Inc. Formulations of tetrahydropyridine antiplatelet agents for parenteral or oral administration
RU2009140792A (ru) * 2007-04-09 2011-05-20 Юсв Лимитед (In) Новые стабильные фармацевтические композиции клопидогрель бисульфата и способ их получения
ES2408380T3 (es) * 2007-04-20 2013-06-20 Wockhardt Limited Composiciones farmacéuticas de clopidogrel
KR20150041173A (ko) * 2007-04-27 2015-04-15 사이덱스 파마슈티칼스, 인크. 클로피도그렐 및 설포알킬 에테르 사이클로덱스트린을 함유하는 제형 및 사용 방법
WO2010009745A1 (en) * 2008-07-25 2010-01-28 Pharmathen S.A. Solid oral dosage form containing anti-platelet agent clopidogrel and method for the preparation thereof
BRPI1009600A2 (zh) 2009-06-25 2016-03-22 Tetra S A
RU2461379C2 (ru) * 2010-12-09 2012-09-20 Закрытое акционерное общество "ФАРМ-ЦЕНТР" (ЗАО "ФАРМ-ЦЕНТР") Фармацевтическая комбинация, обладающая антиагрегантной и липидрегулирующей активностями, фармацевтическая композиция
BR112019015107A2 (pt) * 2017-01-23 2020-03-10 Dong Wha Pharm. Co., Ltd. Formulação de complexo compreendendo inibidor de hmg-coa redutase e clopidogrel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2003478A1 (en) * 1988-12-12 1990-06-12 Leonard G. Dennick Combination of an hmg coa reductase inhibitor and other type of serum cholesterol reducing agent and method for lowering serum cholesterol using such combination
FR2665440B1 (fr) * 1990-07-31 1994-02-04 Lipha Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant.
WO1995011898A1 (en) * 1992-05-12 1995-05-04 Nissan Chemical Industries Ltd. Condensed pyridine type mevalonolactone intermediate and process for its production
WO1995013063A1 (en) * 1993-11-09 1995-05-18 Merck & Co., Inc. HMG-CoA REDUCTASE INHIBITORS IN THE NORMALIZATION OF VASCULAR ENDOTHELIAL DYSFUNCTION
US5945432A (en) * 1995-12-22 1999-08-31 The University Of Vermont And State Agricultural College Thrombolytic agents and thienopyridine derivatives in acute stroke

Also Published As

Publication number Publication date
TW442289B (en) 2001-06-23
DK0914124T3 (da) 2004-05-17
EP0914124A1 (fr) 1999-05-12
PT914124E (pt) 2004-05-31
KR100307268B1 (ko) 2001-09-24
IS2052B (is) 2005-10-14
DE69727299T2 (de) 2004-10-21
JP2000500781A (ja) 2000-01-25
MY125051A (en) 2006-07-31
EP0914124B1 (fr) 2004-01-21
ES2214632T3 (es) 2004-09-16
IL128102A0 (en) 1999-11-30
IS4951A (is) 1999-01-22
NZ333826A (en) 2000-09-29
PL188739B1 (pl) 2005-04-29
CA2261099A1 (fr) 1998-02-05
ID17774A (id) 1998-01-29
AR008782A1 (es) 2000-02-23
CN1109547C (zh) 2003-05-28
CZ17699A3 (cs) 1999-05-12
HU226245B1 (en) 2008-07-28
BR9710560B1 (pt) 2013-12-03
DE69727299D1 (de) 2004-02-26
SI0914124T1 (en) 2004-06-30
ZA976247B (en) 1999-01-15
HUP9903752A3 (en) 2001-12-28
CZ294664B6 (cs) 2005-02-16
NO990321L (no) 1999-03-22
US6218403B1 (en) 2001-04-17
ATE258052T1 (de) 2004-02-15
SK7899A3 (en) 1999-07-12
NO990321D0 (no) 1999-01-25
FR2751540B1 (fr) 1998-10-16
SK284944B6 (sk) 2006-03-02
JP3553610B2 (ja) 2004-08-11
RU2176504C2 (ru) 2001-12-10
AU725949B2 (en) 2000-10-26
CN1228698A (zh) 1999-09-15
EE03853B1 (et) 2002-10-15
NO322894B1 (no) 2006-12-18
FR2751540A1 (fr) 1998-01-30
TR199900154T2 (xx) 1999-04-21
KR20000029484A (ko) 2000-05-25
AU3852697A (en) 1998-02-20
PL331339A1 (en) 1999-07-05
BR9710560A (pt) 1999-08-17
WO1998004259A1 (fr) 1998-02-05
UA58518C2 (uk) 2003-08-15
EE9900028A (et) 1999-08-16
HUP9903752A2 (hu) 2000-03-28
CA2261099C (fr) 2003-04-15
YU3199A (sh) 2002-09-19
RS49504B (sr) 2006-10-27

Similar Documents

Publication Publication Date Title
HK1019405A1 (en) Antithrombotic and antiatherogenic pharmaceutical composition including a thienopyridine derivative and an hmg-coareductase inhibitor
HU9602516D0 (en) Isoprenyl transferase inhibitors
AU6168196A (en) Orthopedic incline appliance and method
IL125103A0 (en) Sputtering targets and method for the preparation thereof
AU5081898A (en) Modular prosthesis
IL121299A0 (en) 4-hydroxy-piperidine derivatives and their uses
IL133784A0 (en) Dolastatin 15 derivatives
HUP9801905A3 (en) Pharmaceutical composition comprising a proteinase inhibitor and a monoglyceride
AU714701C (en) Novel thiophene derivative and pharmaceutical composition thereof
AU6856094A (en) Oxadiazole derivative and medicinal composition thereof
AU2523897A (en) A circulator and components thereof
ZA967800B (en) Heteroaryllsubstituted acryloylguanidine derivatives and pharmaceutical compositions comprising them
IL139775A0 (en) A substituted triazolo-pyridazine derivative and pharmaceutical compositions made therefrom
HUP9602196A3 (en) Sulfonyl- and sulfinyl-benzoyl-guanidine derivatives and pharmaceutical compositions thereof
HRP960271B1 (en) Pharmaceutical composition comprising a proteinase inhibitor and a monoglyceride
AU6438094A (en) Coumarin derivative and use thereof
GB2305363B (en) Shin prosthesis
HUP0000460A3 (en) Imidazopyridazines and pharmaceutical compositions thereof
AU3815695A (en) Substituted bicycloheptanedione derivative and herbicide
AU2405397A (en) Thienopyridine derivatives and their use
GB2317225A9 (en) Location of arrows in a target
HK1024000A1 (en) Micro-particulate form of a tetrahydropyridin derivative
ZA974422B (en) Substituted-amidinobenzene derivative and pharmaceutical compositions thereof.
AU1871097A (en) A condom
AUPN213895A0 (en) Shin and ankle protector

Legal Events

Date Code Title Description
PF Patent in force
CHPA Change of a particular in the register (except of change of ownership)
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150721