HK1016586A1 - Thiazole derivative - Google Patents
Thiazole derivativeInfo
- Publication number
- HK1016586A1 HK1016586A1 HK99101470A HK99101470A HK1016586A1 HK 1016586 A1 HK1016586 A1 HK 1016586A1 HK 99101470 A HK99101470 A HK 99101470A HK 99101470 A HK99101470 A HK 99101470A HK 1016586 A1 HK1016586 A1 HK 1016586A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- thiazole derivative
- thiazole
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20089896 | 1996-07-31 | ||
| PCT/JP1997/002609 WO1998004536A1 (en) | 1996-07-31 | 1997-07-29 | Thiazole derivative as protein kinase c inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1016586A1 true HK1016586A1 (en) | 1999-11-05 |
Family
ID=16432095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK99101470A HK1016586A1 (en) | 1996-07-31 | 1999-04-12 | Thiazole derivative |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6140330A (xx) |
| EP (1) | EP0858452B1 (xx) |
| KR (1) | KR19990063910A (xx) |
| CN (1) | CN1070856C (xx) |
| AR (1) | AR008111A1 (xx) |
| AT (1) | ATE214381T1 (xx) |
| AU (1) | AU695817B2 (xx) |
| BR (1) | BR9706792A (xx) |
| CA (1) | CA2233611A1 (xx) |
| DE (1) | DE69711020T2 (xx) |
| DK (1) | DK0858452T3 (xx) |
| ES (1) | ES2179355T3 (xx) |
| HK (1) | HK1016586A1 (xx) |
| ID (1) | ID19474A (xx) |
| PT (1) | PT858452E (xx) |
| TW (1) | TW513418B (xx) |
| WO (1) | WO1998004536A1 (xx) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849769A (en) * | 1994-08-24 | 1998-12-15 | Medivir Ab | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection |
| GEP20032896B (en) | 1997-10-27 | 2003-02-25 | Agouron Pharma | 4-Aminothiazole Derivatives, Containing Them Pharmaceutical Compositions Inhibiting Cyclin-Dependent Kinases and Methods for Treatment |
| BR9814956A (pt) | 1997-11-10 | 2000-10-03 | Bristol Myers Squibb Co | Inibidores de benzotiazol da tirosina cinase de proteìna |
| JP2002514633A (ja) * | 1998-05-12 | 2002-05-21 | アメリカン・ホーム・プロダクツ・コーポレイション | （２−アシルアミノチアゾール−４−イル）酢酸誘導体 |
| US6407124B1 (en) | 1998-06-18 | 2002-06-18 | Bristol-Myers Squibb Company | Carbon substituted aminothiazole inhibitors of cyclin dependent kinases |
| ES2237919T4 (es) * | 1998-06-18 | 2007-05-01 | Bristol-Myers Squibb Company | Inhibidores aminotiazol sustituidos con carbono de quinasas dependientes de ciclina. |
| GB9823871D0 (en) | 1998-10-30 | 1998-12-23 | Pharmacia & Upjohn Spa | 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents |
| US6114365A (en) | 1999-08-12 | 2000-09-05 | Pharmacia & Upjohn S.P.A. | Arylmethyl-carbonylamino-thiazole derivatives, process for their preparation, and their use as antitumor agents |
| TWI284639B (en) * | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
| WO2001056567A1 (en) * | 2000-02-04 | 2001-08-09 | Novo Nordisk A/S | 2,4-diaminothiazole derivatives and their use as glycogen synthase kinase-3 (gsk-3) inhibitors |
| AU2001236698A1 (en) * | 2000-02-07 | 2001-08-14 | Abbott Gesellschaft Mit Beschrankter Haftung & Company Kommanditgesellschaft | 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors |
| US20030176443A1 (en) * | 2001-05-16 | 2003-09-18 | Matthias Stein-Gerlach | Pyridylpyrimidine derivatives as effective compounds against prion diseases |
| HN2002000156A (es) | 2001-07-06 | 2003-11-27 | Inc Agouron Pharmaceuticals | Derivados de benzamida tiazol y composiciones farmaceuticas para inhibir la proliferacion de celulas y metodos para su utilización. |
| EP1724270A3 (en) | 2001-07-19 | 2007-01-03 | Pfizer Italia S.r.l. | Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents |
| AU2002368473A1 (en) * | 2002-01-25 | 2004-09-09 | Pharmacia Corporation | Aldosterone blocker therapy to prevent or treat inflammation-related disorders |
| US7101898B2 (en) * | 2002-02-01 | 2006-09-05 | Novo Nordisk A/S | Amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes |
| CN102796058B (zh) * | 2003-08-12 | 2015-05-13 | 盐野义制药株式会社 | 具有血小板生成素受体激动作用的化合物 |
| US7910613B2 (en) * | 2004-09-22 | 2011-03-22 | H. Lundbeck A/S | 2-acylaminothiazole derivatives |
| US7674912B2 (en) * | 2005-04-25 | 2010-03-09 | H. Lundbeck A/S | Pro-drugs of N-thiazol-2-yl-benzamide derivatives |
| CN101553493B (zh) * | 2006-07-19 | 2012-07-04 | 阿斯利康(瑞典)有限公司 | 三环螺哌啶化合物、它们的合成和它们作为趋化因子受体活性调节剂的用途 |
| WO2009011654A1 (en) * | 2007-07-17 | 2009-01-22 | Astrazeneca Ab | Process for the preparation of cyclic spiropiperidines |
| WO2009120826A1 (en) * | 2008-03-27 | 2009-10-01 | Wyeth | 2-aryl- and 2-heteroarylthiazolyl compounds, methods for their preparation and use thereof |
| EP2470539A1 (en) * | 2009-08-28 | 2012-07-04 | Array Biopharma, Inc. | Raf inhibitor compounds and methods of use thereof |
| EA023040B1 (ru) * | 2010-07-02 | 2016-04-29 | Джилид Сайэнс, Инк. | Ингибиторы киназ, регулирующих апоптозный сигнал |
| EP2670740B1 (en) * | 2011-02-04 | 2015-12-30 | Council of Scientific and Industrial Research | Amidobenzothiazoles and process for the preparation thereof |
| ES2489297B1 (es) * | 2013-01-22 | 2015-06-10 | Consejo Superior De Investigaciones Científicas (Csic) | Benzotiazoles sustituidos y sus aplicaciones terapeuticas para el tratamiento de enfermedades humanas |
| GB201401886D0 (en) | 2014-02-04 | 2014-03-19 | Lytix Biopharma As | Neurodegenerative therapies |
| CN110317230B (zh) * | 2018-03-30 | 2023-11-07 | 上海昇悦医药科技有限公司 | 磷酸盐类衍生物及其用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0063564A1 (en) * | 1980-11-04 | 1982-11-03 | ANDERSON, Martin C. | Basic color media set for providing tonally matched palettes |
| US4957932A (en) * | 1987-11-25 | 1990-09-18 | Merck Frosst Canada, Inc. | Benzoheterazoles |
| IL90337A0 (en) * | 1988-05-24 | 1989-12-15 | Pfizer | Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents |
| JP2869561B2 (ja) * | 1989-05-22 | 1999-03-10 | 大塚製薬株式会社 | 血小板粘着抑制剤 |
| TW205041B (xx) * | 1989-08-07 | 1993-05-01 | Fujisawa Pharmaceutical Co | |
| AU3884993A (en) * | 1992-04-10 | 1993-11-18 | Merck Frosst Canada Inc. | Benzothiazole-substituted benzyl alcohols as leukotriene antagonists |
| WO1993021168A1 (en) * | 1992-04-10 | 1993-10-28 | Merck Frosst Canada Inc. | Thiazole-substituted benzyl alcohols as leukotriene antagonists |
| KR0134069B1 (ko) * | 1993-02-19 | 1998-04-22 | 유미꾸라 레이이찌 | 벤조티아졸 술폰아미드 유도체, 그의 제조법 및 그의 용도 |
-
1997
- 1997-07-28 TW TW086110703A patent/TW513418B/zh not_active IP Right Cessation
- 1997-07-29 ES ES97933046T patent/ES2179355T3/es not_active Expired - Lifetime
- 1997-07-29 CN CN97190997A patent/CN1070856C/zh not_active Expired - Fee Related
- 1997-07-29 KR KR1019980702383A patent/KR19990063910A/ko not_active Application Discontinuation
- 1997-07-29 US US09/043,642 patent/US6140330A/en not_active Expired - Fee Related
- 1997-07-29 WO PCT/JP1997/002609 patent/WO1998004536A1/en not_active Application Discontinuation
- 1997-07-29 DE DE69711020T patent/DE69711020T2/de not_active Expired - Fee Related
- 1997-07-29 BR BR9706792-0A patent/BR9706792A/pt not_active Application Discontinuation
- 1997-07-29 AU AU36354/97A patent/AU695817B2/en not_active Ceased
- 1997-07-29 PT PT97933046T patent/PT858452E/pt unknown
- 1997-07-29 EP EP97933046A patent/EP0858452B1/en not_active Expired - Lifetime
- 1997-07-29 AT AT97933046T patent/ATE214381T1/de not_active IP Right Cessation
- 1997-07-29 CA CA002233611A patent/CA2233611A1/en not_active Abandoned
- 1997-07-29 DK DK97933046T patent/DK0858452T3/da active
- 1997-07-30 AR ARP970103439A patent/AR008111A1/es not_active Application Discontinuation
- 1997-07-31 ID IDP972653A patent/ID19474A/id unknown
-
1999
- 1999-04-12 HK HK99101470A patent/HK1016586A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ID19474A (id) | 1998-07-16 |
| DE69711020D1 (de) | 2002-04-18 |
| PT858452E (pt) | 2002-07-31 |
| BR9706792A (pt) | 2001-11-27 |
| CN1198160A (zh) | 1998-11-04 |
| KR19990063910A (ko) | 1999-07-26 |
| CN1070856C (zh) | 2001-09-12 |
| WO1998004536A1 (en) | 1998-02-05 |
| TW513418B (en) | 2002-12-11 |
| EP0858452B1 (en) | 2002-03-13 |
| ES2179355T3 (es) | 2003-01-16 |
| US6140330A (en) | 2000-10-31 |
| DE69711020T2 (de) | 2002-11-21 |
| AU3635497A (en) | 1998-02-20 |
| CA2233611A1 (en) | 1998-02-05 |
| ATE214381T1 (de) | 2002-03-15 |
| AR008111A1 (es) | 1999-12-09 |
| EP0858452A1 (en) | 1998-08-19 |
| AU695817B2 (en) | 1998-08-20 |
| DK0858452T3 (da) | 2002-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20050729 |