HK1014546A1 - Recombinant prrs proteins, diagnostic kits and vaccines containing said recombinant proteins. - Google Patents

Recombinant prrs proteins, diagnostic kits and vaccines containing said recombinant proteins.

Info

Publication number
HK1014546A1
HK1014546A1 HK98115793A HK98115793A HK1014546A1 HK 1014546 A1 HK1014546 A1 HK 1014546A1 HK 98115793 A HK98115793 A HK 98115793A HK 98115793 A HK98115793 A HK 98115793A HK 1014546 A1 HK1014546 A1 HK 1014546A1
Authority
HK
Hong Kong
Prior art keywords
recombinant
proteins
prrs
prrsv
diagnostic kits
Prior art date
Application number
HK98115793A
Other languages
English (en)
Inventor
Juan Plana Duran
Jose Ignacio Casal Alvarez
Isabel Climent Sanchez
Original Assignee
Wyeth Farma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES09401027A external-priority patent/ES2078187B1/es
Application filed by Wyeth Farma Sa filed Critical Wyeth Farma Sa
Publication of HK1014546A1 publication Critical patent/HK1014546A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/815Viral vaccine for porcine species, e.g. swine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK98115793A 1994-05-13 1998-12-28 Recombinant prrs proteins, diagnostic kits and vaccines containing said recombinant proteins. HK1014546A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES09401027A ES2078187B1 (es) 1994-05-13 1994-05-13 Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes.
ES09500815A ES2085837B1 (es) 1994-05-13 1995-04-27 Proteinas recombinantes de prrsv, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes
PCT/ES1995/000053 WO1995031550A1 (es) 1994-05-13 1995-05-10 Proteinas recombinantes de prrsv, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes

Publications (1)

Publication Number Publication Date
HK1014546A1 true HK1014546A1 (en) 1999-11-05

Family

ID=26154789

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98115793A HK1014546A1 (en) 1994-05-13 1998-12-28 Recombinant prrs proteins, diagnostic kits and vaccines containing said recombinant proteins.

Country Status (16)

Country Link
US (1) US5888513A (xx)
EP (1) EP0717108B1 (xx)
JP (1) JPH09500544A (xx)
AT (1) ATE280829T1 (xx)
AU (1) AU699385B2 (xx)
CA (1) CA2167080C (xx)
DE (2) DE69533690T2 (xx)
DK (2) DK53595A (xx)
FR (1) FR2719845B1 (xx)
GB (1) GB2289279B (xx)
HK (1) HK1014546A1 (xx)
IT (1) IT1277996B1 (xx)
NL (1) NL1000365C2 (xx)
PT (1) PT717108E (xx)
TW (1) TW450977B (xx)
WO (1) WO1995031550A1 (xx)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103460C (en) 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
ES2122921B1 (es) * 1996-12-30 1999-09-16 Inmunologia & Genetica Aplic Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico.
ATE365746T1 (de) * 1997-05-06 2007-07-15 Boehringer Ingelheim Vetmed Prrsv-antigene, die auf peptidsequenzen des prrs- virus basieren, für die verwendung als impfstoff und für diagnostische tests
US6391314B1 (en) * 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
DE69921530T2 (de) * 1998-03-02 2005-10-27 Eli Lilly And Co., Indianapolis Behandlung einer Virusinfektion bei Schweinen
AU769539B2 (en) * 1999-01-29 2004-01-29 Zoetis Services Llc Adjuvants for use in vaccines
CA2366072C (en) 1999-03-08 2007-07-10 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
ES2348159T3 (es) 1999-04-22 2010-11-30 United States Department Of Agriculture Vacuna contra el sindrome respiratorio y reproductivo porcino basada en el aislado ja-142.
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
JP2003533989A (ja) * 2000-05-24 2003-11-18 メリアル ブタ生殖・呼吸症候群ウィルス(prrsv)の組換えポックスウィルスワクチン
WO2002067985A1 (en) * 2001-02-23 2002-09-06 The Board Of Regents Of The University Of Nebraska Method for prophylaxis and treatment of porcine reproductive and respiratory syndrome
JP2005075752A (ja) * 2003-08-29 2005-03-24 Nippon Inst For Biological Science 豚繁殖・呼吸障害症候群用ワクチン製剤
RU2007101725A (ru) 2004-06-18 2008-07-27 Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) Идентификация инфицированных вирусом и вакцинированных вирусом организмов
US20080268426A1 (en) * 2004-06-18 2008-10-30 Regents Of The University Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
CA2894069C (en) 2005-06-24 2019-02-26 Regents Of The University Of Minnesota Prrs viruses, infectious clones, mutants thereof, and methods of use
US7241582B2 (en) 2005-07-05 2007-07-10 Mj Biologics, Inc. Diagnostic test kits
EP1792996A1 (en) * 2005-12-01 2007-06-06 Consejo Superior de Investigaciones Cientificas Nucleic acid sequences encoding vaccines against Porcine reproductive and respiratory syndrome virus (PRRSV)
RU2561595C2 (ru) * 2008-08-25 2015-08-27 Бёрингер Ингельхайм Ветмедика, Инк. Вакцина против высокопатогенного репродуктивно-респираторного синдрома свиней (hp prrs)
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物
EP2488872B1 (en) * 2009-10-13 2014-04-16 Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. Methods for prrsv detection
CN101899421B (zh) * 2010-03-01 2012-09-19 中国农业科学院上海兽医研究所 重组杆状病毒及其构建方法和应用
CN101792740B (zh) * 2010-04-07 2012-05-30 西北农林科技大学 表达prrsv免疫原基因的重组杆状病毒及其制备和应用
TWI417385B (zh) * 2010-05-04 2013-12-01 Univ Nat Taiwan 以植物生產之豬生殖與呼吸道綜合症口服疫苗及其用途
EA038012B1 (ru) 2011-02-17 2021-06-23 Бёрингер Ингельхайм Ветмедика Гмбх Композиция на основе нового штамма prrsv или его белков, продукт, их применение, вирус prrsv, выделенная нк и рекомбинантный вектор экспрессии для получения этого вируса
SG192821A1 (en) 2011-02-17 2013-09-30 Boehringer Ingelheim Vetmed Commercial scale process for production of prrsv
BR112013028605A2 (pt) 2011-05-07 2017-01-17 Avi Mex S A De C V Lab vetor viral, vacina recombinante contra prrs e uso de uma vacina
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
EP2737058A1 (en) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
WO2015048115A1 (en) 2013-09-25 2015-04-02 Zoetis Llc Pcv2b divergent vaccine composition and methods of use
JP6886291B2 (ja) 2013-12-20 2021-06-16 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH PRRSウイルス変異株、ヨーロッパ型PRRSウイルスcDNAクローンおよびそれらの使用
US10279031B2 (en) 2016-05-11 2019-05-07 Phibro Animal Health Corporation Composition comprising antigens and a mucosal adjuvant and a method for using
WO2020138761A1 (ko) * 2018-12-27 2020-07-02 주식회사 바이오포아 돼지 생식기 및 호흡기 증후군 바이러스의 키메라 바이러스 및 이를 이용한 백신
CN111996213A (zh) * 2020-02-06 2020-11-27 广西大学 猪繁殖与呼吸综合征病毒双荧光标记基因重组毒株的构建方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103460C (en) * 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
KR0138092B1 (ko) * 1991-08-26 1998-04-30 제임스 씨. 데세사레 미확인(Mystery) 돼지 질병 관련 바이러스제
KR100241221B1 (ko) * 1991-08-26 2000-03-02 에드워드 콜린스 제임스 돼지 불임 및 호흡기계 중후백신 및 그의 진단법
AU2684792A (en) * 1991-10-14 1993-05-21 Akzo Nobel N.V. Porcine reproductive respiratory syndrome vaccine and diagnostic
FR2682966B1 (fr) * 1991-10-29 1994-12-02 Rhone Merieux Preparation d'antigenes et de vaccins du virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
FR2686097B1 (fr) * 1992-01-14 1994-12-30 Rhone Merieux Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.

Also Published As

Publication number Publication date
AU699385B2 (en) 1998-12-03
WO1995031550A1 (es) 1995-11-23
DK53595A (da) 1995-11-14
DE69533690D1 (de) 2004-12-02
JPH09500544A (ja) 1997-01-21
ATE280829T1 (de) 2004-11-15
EP0717108B1 (en) 2004-10-27
CA2167080C (en) 2006-12-12
GB2289279A (en) 1995-11-15
ITTO950367A0 (it) 1995-05-10
EP0717108A1 (en) 1996-06-19
IT1277996B1 (it) 1997-11-12
DE19517773A1 (de) 1995-11-16
NL1000365A1 (nl) 1995-11-13
DK0717108T3 (da) 2005-01-31
FR2719845A1 (fr) 1995-11-17
DE69533690T2 (de) 2006-03-09
TW450977B (en) 2001-08-21
US5888513A (en) 1999-03-30
AU2409495A (en) 1995-12-05
GB9509392D0 (en) 1995-06-28
ITTO950367A1 (it) 1996-11-10
CA2167080A1 (en) 1995-11-23
FR2719845B1 (fr) 1997-05-23
NL1000365C2 (nl) 1996-10-02
GB2289279B (en) 1998-09-16
PT717108E (pt) 2005-01-31

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PE Patent expired

Effective date: 20150509