DE69533690D1 - Recombinante prrs viren -proteine und dieselben diagnosesätze und impfstoffe enthaltenden - Google Patents

Recombinante prrs viren -proteine und dieselben diagnosesätze und impfstoffe enthaltenden

Info

Publication number
DE69533690D1
DE69533690D1 DE69533690T DE69533690T DE69533690D1 DE 69533690 D1 DE69533690 D1 DE 69533690D1 DE 69533690 T DE69533690 T DE 69533690T DE 69533690 T DE69533690 T DE 69533690T DE 69533690 D1 DE69533690 D1 DE 69533690D1
Authority
DE
Germany
Prior art keywords
prrsv
prrs
diagnostic kit
prrs virus
virus proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69533690T
Other languages
English (en)
Other versions
DE69533690T2 (de
Inventor
Duran Juan Plana
Alvarez Jose Ignacio Casal
Sanchez Isabel Climent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Farma SA
Original Assignee
Wyeth Farma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES09401027A external-priority patent/ES2078187B1/es
Application filed by Wyeth Farma SA filed Critical Wyeth Farma SA
Application granted granted Critical
Publication of DE69533690D1 publication Critical patent/DE69533690D1/de
Publication of DE69533690T2 publication Critical patent/DE69533690T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/815—Viral vaccine for porcine species, e.g. swine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69533690T 1994-05-13 1995-05-10 Recombinante prrs viren -proteine und dieselben diagnosesätze und impfstoffe enthaltenden Expired - Lifetime DE69533690T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
ES9401027 1994-05-13
ES09401027A ES2078187B1 (es) 1994-05-13 1994-05-13 Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes.
ES09500815A ES2085837B1 (es) 1994-05-13 1995-04-27 Proteinas recombinantes de prrsv, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes
ES9500815 1995-04-27
PCT/ES1995/000053 WO1995031550A1 (es) 1994-05-13 1995-05-10 Proteinas recombinantes de prrsv, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes

Publications (2)

Publication Number Publication Date
DE69533690D1 true DE69533690D1 (de) 2004-12-02
DE69533690T2 DE69533690T2 (de) 2006-03-09

Family

ID=26154789

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69533690T Expired - Lifetime DE69533690T2 (de) 1994-05-13 1995-05-10 Recombinante prrs viren -proteine und dieselben diagnosesätze und impfstoffe enthaltenden
DE19517773A Ceased DE19517773A1 (de) 1994-05-13 1995-05-15 Rekombinante PRRSV-Proteine, Diagnostik-Kits und solche rekombinanten PRRSV-Proteine enthaltenden Vakzinen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19517773A Ceased DE19517773A1 (de) 1994-05-13 1995-05-15 Rekombinante PRRSV-Proteine, Diagnostik-Kits und solche rekombinanten PRRSV-Proteine enthaltenden Vakzinen

Country Status (16)

Country Link
US (1) US5888513A (de)
EP (1) EP0717108B1 (de)
JP (1) JPH09500544A (de)
AT (1) ATE280829T1 (de)
AU (1) AU699385B2 (de)
CA (1) CA2167080C (de)
DE (2) DE69533690T2 (de)
DK (2) DK53595A (de)
FR (1) FR2719845B1 (de)
GB (1) GB2289279B (de)
HK (1) HK1014546A1 (de)
IT (1) IT1277996B1 (de)
NL (1) NL1000365C2 (de)
PT (1) PT717108E (de)
TW (1) TW450977B (de)
WO (1) WO1995031550A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103460C (en) 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (de) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren
ES2122921B1 (es) * 1996-12-30 1999-09-16 Inmunologia & Genetica Aplic Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico.
DE69837992T2 (de) * 1997-05-06 2008-03-20 Boehringer Ingelheim Vetmedica Gmbh Prrsv-antigene, die auf peptidsequenzen des prrs-virus basieren, für die verwendung als impfstoff und für diagnostische tests
US6391314B1 (en) * 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
ES2230802T3 (es) * 1998-03-02 2005-05-01 Eli Lilly And Company Tratamiento de infeccion viral en cercos.
AU769539B2 (en) 1999-01-29 2004-01-29 Zoetis Services Llc Adjuvants for use in vaccines
JP3961222B2 (ja) 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Ｐｒｒｓｖワクチン
CA2370372C (en) 1999-04-22 2009-02-24 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
KR20030036194A (ko) * 2000-05-24 2003-05-09 메리알 돼지 생식기 호흡기 증후군 바이러스(ｐｒｒｓｖ) 재조합아비폭스바이러스 백신
US20030017448A1 (en) * 2001-02-23 2003-01-23 The Board Of Regents Of The University Of Nebraska Method of prophylaxis and treatment of porcine reproductive and respiratory syndrome
JP2005075752A (ja) * 2003-08-29 2005-03-24 Nippon Inst For Biological Science 豚繁殖・呼吸障害症候群用ワクチン製剤
AR049924A1 (es) 2004-06-18 2006-09-13 Univ Minnesota Identificacion de organismos viralmente infectados y vacunados
US20080268426A1 (en) * 2004-06-18 2008-10-30 Regents Of The University Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
ES2386973T3 (es) 2005-06-24 2012-09-10 Regents Of The University Of Minnesota Virus PRRS, clones infecciosos, mutantes de los mismos, y métodos de utilización
US7241582B2 (en) * 2005-07-05 2007-07-10 Mj Biologics, Inc. Diagnostic test kits
EP1792996A1 (de) * 2005-12-01 2007-06-06 Consejo Superior de Investigaciones Cientificas Nukleinsäuren, kodierend für Impfstoffe gegen den reproduktiven und respiratorischen Syndrom Virus (prrsv)
MX2011002046A (es) * 2008-08-25 2011-04-21 Boehringer Ingelheim Vetmed Vacuna contra sindrome disgenesico y respiratorio porcino altamente patogeno (hp prrs).
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
WO2011045056A1 (en) * 2009-10-13 2011-04-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Methods for prrsv detection
CN101899421B (zh) * 2010-03-01 2012-09-19 中国农业科学院上海兽医研究所 重组杆状病毒及其构建方法和应用
CN101792740B (zh) * 2010-04-07 2012-05-30 西北农林科技大学 表达prrsv免疫原基因的重组杆状病毒及其制备和应用
TWI417385B (zh) * 2010-05-04 2013-12-01 Univ Nat Taiwan 以植物生產之豬生殖與呼吸道綜合症口服疫苗及其用途
DK2675476T3 (en) 2011-02-17 2015-12-14 Boehringer Ingelheim Vetmed Process for producing PRRSV on a commercial scale
ME02271B (me) 2011-02-17 2016-02-20 Boehringer Ingelheim Vetmedica Gmbh Novi evropski prrsv soj
EP2712927B1 (de) 2011-05-07 2019-08-21 Laboratorio Avi-Mex, S.A. De C.V. Rekombinanter impfstoff gegen prrs in einem virusvektor
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
EP2968513A2 (de) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Prrs-virus, zusammensetzungen, impfstoff und verfahren zur verwendung
JP6821429B2 (ja) 2013-09-25 2021-01-27 ゾエティス・サービシーズ・エルエルシー Ｐｃｖ２ｂ分岐ワクチン組成物及び使用方法
HUE061768T2 (hu) 2013-12-20 2023-08-28 Boehringer Ingelheim Vetmedica Gmbh PRRS virus variáns, európai PRRS virus cDNS klón, és alkalmazásuk
US10279031B2 (en) 2016-05-11 2019-05-07 Phibro Animal Health Corporation Composition comprising antigens and a mucosal adjuvant and a method for using
WO2020138761A1 (ko) * 2018-12-27 2020-07-02 주식회사 바이오포아 돼지 생식기 및 호흡기 증후군 바이러스의 키메라 바이러스 및 이를 이용한 백신
CN111996213A (zh) * 2020-02-06 2020-11-27 广西大学 猪繁殖与呼吸综合征病毒双荧光标记基因重组毒株的构建方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103460C (en) * 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
CA2116348C (en) * 1991-08-26 2001-07-03 James E. Collins Sirs vaccine and diagnosis method
CA2076744C (en) * 1991-08-26 2000-06-27 Danny W. Chladek Viral agent associated with mystery swine disease
WO1993007898A1 (en) * 1991-10-14 1993-04-29 Akzo Nobel N.V. Porcine reproductive respiratory syndrome vaccine and diagnostic
FR2682966B1 (fr) * 1991-10-29 1994-12-02 Rhone Merieux Preparation d'antigenes et de vaccins du virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
FR2686097B1 (fr) * 1992-01-14 1994-12-30 Rhone Merieux Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.

Also Published As

Publication number Publication date
FR2719845B1 (fr) 1997-05-23
ITTO950367A0 (it) 1995-05-10
GB2289279A (en) 1995-11-15
CA2167080A1 (en) 1995-11-23
AU2409495A (en) 1995-12-05
AU699385B2 (en) 1998-12-03
HK1014546A1 (en) 1999-11-05
TW450977B (en) 2001-08-21
JPH09500544A (ja) 1997-01-21
DK0717108T3 (da) 2005-01-31
ITTO950367A1 (it) 1996-11-10
CA2167080C (en) 2006-12-12
US5888513A (en) 1999-03-30
WO1995031550A1 (es) 1995-11-23
DE69533690T2 (de) 2006-03-09
GB2289279B (en) 1998-09-16
GB9509392D0 (en) 1995-06-28
DK53595A (da) 1995-11-14
NL1000365A1 (nl) 1995-11-13
NL1000365C2 (nl) 1996-10-02
ATE280829T1 (de) 2004-11-15
EP0717108B1 (de) 2004-10-27
FR2719845A1 (fr) 1995-11-17
IT1277996B1 (it) 1997-11-12
DE19517773A1 (de) 1995-11-16
PT717108E (pt) 2005-01-31
EP0717108A1 (de) 1996-06-19

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Legal Events

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