TH13688B - การเอ็กซ์เพรสโพลีเพพไทด์ของไวรัสก่อโรคทางระบบหายใจที่แพร่พันธุ์ได้ในสุกรในเซลล์เดียวกัน - Google Patents
การเอ็กซ์เพรสโพลีเพพไทด์ของไวรัสก่อโรคทางระบบหายใจที่แพร่พันธุ์ได้ในสุกรในเซลล์เดียวกันInfo
- Publication number
- TH13688B TH13688B TH9601000696A TH9601000696A TH13688B TH 13688 B TH13688 B TH 13688B TH 9601000696 A TH9601000696 A TH 9601000696A TH 9601000696 A TH9601000696 A TH 9601000696A TH 13688 B TH13688 B TH 13688B
- Authority
- TH
- Thailand
- Prior art keywords
- orf
- prrsv
- virus
- protein
- proteins
- Prior art date
Links
- 241000282887 Suidae Species 0.000 title 1
- 244000052769 pathogen Species 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000001850 reproductive effect Effects 0.000 title 1
- 101000787133 Acidithiobacillus ferridurans Uncharacterized 12.3 kDa protein in mobL 3'region Proteins 0.000 claims abstract 14
- 101000787132 Acidithiobacillus ferridurans Uncharacterized 8.2 kDa protein in mobL 3'region Proteins 0.000 claims abstract 14
- 101000827262 Acidithiobacillus ferrooxidans Uncharacterized 18.9 kDa protein in mobE 3'region Proteins 0.000 claims abstract 14
- 101000811747 Antithamnion sp. UPF0051 protein in atpA 3'region Proteins 0.000 claims abstract 14
- 101000827603 Bacillus phage SPP1 Uncharacterized 10.2 kDa protein in GP2-GP6 intergenic region Proteins 0.000 claims abstract 14
- 101000827607 Bacillus phage SPP1 Uncharacterized 8.5 kDa protein in GP2-GP6 intergenic region Proteins 0.000 claims abstract 14
- 101000961975 Bacillus thuringiensis Uncharacterized 13.4 kDa protein Proteins 0.000 claims abstract 14
- 101000964407 Caldicellulosiruptor saccharolyticus Uncharacterized 10.7 kDa protein in xynB 3'region Proteins 0.000 claims abstract 14
- 101000768777 Haloferax lucentense (strain DSM 14919 / JCM 9276 / NCIMB 13854 / Aa 2.2) Uncharacterized 50.6 kDa protein in the 5'region of gyrA and gyrB Proteins 0.000 claims abstract 14
- 101000607404 Infectious laryngotracheitis virus (strain Thorne V882) Protein UL24 homolog Proteins 0.000 claims abstract 14
- 101000735632 Klebsiella pneumoniae Uncharacterized 8.8 kDa protein in aacA4 3'region Proteins 0.000 claims abstract 14
- 101000977786 Lymantria dispar multicapsid nuclear polyhedrosis virus Uncharacterized 9.7 kDa protein in PE 3'region Proteins 0.000 claims abstract 14
- 101001113905 Rice tungro bacilliform virus (isolate Philippines) Protein P4 Proteins 0.000 claims abstract 14
- 101000818100 Spirochaeta aurantia Uncharacterized 12.7 kDa protein in trpE 5'region Proteins 0.000 claims abstract 14
- 101001037658 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) Glucokinase Proteins 0.000 claims abstract 14
- 101000977023 Azospirillum brasilense Uncharacterized 17.8 kDa protein in nodG 5'region Proteins 0.000 claims abstract 10
- 101000961984 Bacillus thuringiensis Uncharacterized 30.3 kDa protein Proteins 0.000 claims abstract 10
- 101000644901 Drosophila melanogaster Putative 115 kDa protein in type-1 retrotransposable element R1DM Proteins 0.000 claims abstract 10
- 101000747702 Enterobacteria phage N4 Uncharacterized protein Gp2 Proteins 0.000 claims abstract 10
- 101000758599 Escherichia coli Uncharacterized 14.7 kDa protein Proteins 0.000 claims abstract 10
- 101000768930 Lactococcus lactis subsp. cremoris Uncharacterized protein in pepC 5'region Proteins 0.000 claims abstract 10
- 101000976302 Leptospira interrogans Uncharacterized protein in sph 3'region Proteins 0.000 claims abstract 10
- 101000778886 Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) Uncharacterized protein LA_2151 Proteins 0.000 claims abstract 10
- 101001121571 Rice tungro bacilliform virus (isolate Philippines) Protein P2 Proteins 0.000 claims abstract 10
- 101000818098 Spirochaeta aurantia Uncharacterized protein in trpE 3'region Proteins 0.000 claims abstract 10
- 101001026590 Streptomyces cinnamonensis Putative polyketide beta-ketoacyl synthase 2 Proteins 0.000 claims abstract 10
- 101000750896 Synechococcus elongatus (strain PCC 7942 / FACHB-805) Uncharacterized protein Synpcc7942_2318 Proteins 0.000 claims abstract 10
- 101000916321 Xenopus laevis Transposon TX1 uncharacterized 149 kDa protein Proteins 0.000 claims abstract 10
- 101000760088 Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1) 20.9 kDa protein Proteins 0.000 claims abstract 10
- 238000000034 method Methods 0.000 claims abstract 4
- 241000700605 Viruses Species 0.000 claims 10
- 239000013598 vector Substances 0.000 claims 7
- 239000012634 fragment Substances 0.000 claims 5
- 239000003085 diluting agent Substances 0.000 claims 3
- 230000002163 immunogen Effects 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 101000895926 Streptomyces plicatus Endo-beta-N-acetylglucosaminidase H Proteins 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 101000802734 Homo sapiens eIF5-mimic protein 2 Proteins 0.000 claims 1
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 102100035859 eIF5-mimic protein 2 Human genes 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 150000007523 nucleic acids Chemical group 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 230000000644 propagated effect Effects 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 241000701447 unidentified baculovirus Species 0.000 claims 1
- 239000013603 viral vector Substances 0.000 claims 1
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
Abstract
การประดิษฐ์นี้ให้กระบวนการสำหรับการสร้างรีคอมบิแนนท์ดีเอ็นเอของโปรตีน ORF 3 หรือ ORF 4 ของ PRRSV ที่โตเต็มที่ ซึ่งทำได้โดยการโคเอ็กซ์เพรสโปรตีน ORF 2, ORF 3 และ ORF 4 ของ PRRSV ด้วยเซลล์เดียวกัน
Claims (2)
1. ส่วนประกอบอิมมูโนเจน ที่ประกอบด้วยโปรตีนของ PRRSV ที่ทนต่อ endo-H อย่างน้อยหนึ่ง ชนิด ที่เลือกมาจากกลุ่มที่มี ORF 3 และ ORF 4 ร่วมกับสารพาหรือสารทำให้เจือจางที่ใช้ได้ทางยา 1
2. ส่วนประกอบอิมมูโนเจน ที่ประกอบด้วยเวกเตอร์ไวรัสอย่างน้อยหนึ่งชนิด จะเอกซ์เพรสโปรตีน ORF 2 ORF 3 และ ORF 4 โดยลำพังหรือร่วมกัน ในเซลล์ ที่รวมกับตัวนำพาหรือสารทำให้เจือจางที่ใช้ ได้ทางยา
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH22679A TH22679A (th) | 1996-12-27 |
| TH13688B true TH13688B (th) | 2002-10-18 |
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