HK1013629A1 - Structual gene of pneumococcal protein - Google Patents

Structual gene of pneumococcal protein

Info

Publication number
HK1013629A1
HK1013629A1 HK98115032A HK98115032A HK1013629A1 HK 1013629 A1 HK1013629 A1 HK 1013629A1 HK 98115032 A HK98115032 A HK 98115032A HK 98115032 A HK98115032 A HK 98115032A HK 1013629 A1 HK1013629 A1 HK 1013629A1
Authority
HK
Hong Kong
Prior art keywords
nucleic acid
pneumococcal protein
structual
gene
pspa
Prior art date
Application number
HK98115032A
Other languages
English (en)
Inventor
David E Briles
Janet L Yother
Larry S Mcdaniel
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of HK1013629A1 publication Critical patent/HK1013629A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Insulating Materials (AREA)
HK98115032A 1991-02-15 1998-12-23 Structual gene of pneumococcal protein HK1013629A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65677391A 1991-02-15 1991-02-15
PCT/US1992/000857 WO1992014488A1 (en) 1991-02-15 1992-02-12 Structural gene of pneumococcal protein

Publications (1)

Publication Number Publication Date
HK1013629A1 true HK1013629A1 (en) 1999-11-26

Family

ID=24634503

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98115032A HK1013629A1 (en) 1991-02-15 1998-12-23 Structual gene of pneumococcal protein

Country Status (16)

Country Link
US (1) US5728387A (xx)
EP (2) EP0786521A1 (xx)
JP (3) JP3215109B2 (xx)
AT (1) ATE168132T1 (xx)
AU (1) AU692678C (xx)
CA (1) CA2104014C (xx)
DE (1) DE69226167T2 (xx)
DK (1) DK0571538T5 (xx)
ES (1) ES2118812T3 (xx)
FI (1) FI933580A (xx)
HK (1) HK1013629A1 (xx)
IE (2) IE920479A1 (xx)
IL (1) IL100946A0 (xx)
NO (1) NO313999B1 (xx)
WO (1) WO1992014488A1 (xx)
ZA (1) ZA921025B (xx)

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US5980909A (en) * 1991-02-15 1999-11-09 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
US6027734A (en) * 1991-02-15 2000-02-22 Uab Research Foundation Mucosal administration of pneumococcal antigens
US6232116B1 (en) 1991-02-15 2001-05-15 University Of Alabama At Birmingham Research Foundation Oral administration of pneumococcal antigens
US6231870B1 (en) * 1995-06-02 2001-05-15 Uab Research Foundation Oral administration of pneumoccal antigens
US5965141A (en) * 1991-02-15 1999-10-12 Uab Research Foundation Epitopic regions of pneumococcal surface protein a
CA2116261A1 (en) * 1993-04-20 1994-10-21 David E. Briles Epitopic regions of pneumococcal surface protein a
US5928900A (en) * 1993-09-01 1999-07-27 The Rockefeller University Bacterial exported proteins and acellular vaccines based thereon
AU734488B2 (en) * 1994-05-20 2001-06-14 Uab Research Foundation Mucosal administration of pneumococcal antigens
US6001564A (en) * 1994-09-12 1999-12-14 Infectio Diagnostic, Inc. Species specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US20020055101A1 (en) 1995-09-11 2002-05-09 Michel G. Bergeron Specific and universal probes and amplification primers to rapidly detect and identify common bacterial pathogens and antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US6004802A (en) * 1995-06-02 1999-12-21 University Of Alabama At Birmingham Oral administration of pneumococcal antigens
AU709368B2 (en) * 1995-06-02 1999-08-26 Uab Research Foundation Oral administration of pneumococcal antigens
US6251405B1 (en) 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
EA199800046A1 (ru) * 1995-06-07 1998-06-25 Байокем Вэксинс Инк. Полипептид, последовательность днк, вакцинная композиция (варианты), антитело или его фрагмент, вакцина, применения указанных полипептида, последовательности днк и антитела или его фрагмента
ES2271954T3 (es) * 1995-06-07 2007-04-16 Sanofi Pasteur Inc. Expresion de lipoproteinas.
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US5994066A (en) * 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US7078042B2 (en) 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
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US6165989A (en) 1996-05-14 2000-12-26 Smithkline Beecham Corporation Era of Streptococcus pneumoniae
AU737243B2 (en) 1996-07-03 2001-08-16 Merial, Inc. Recombinant canine adenovirus (CAV) containing exogenous DNA
US5928895A (en) * 1996-09-24 1999-07-27 Smithkline Beecham Corporation IgA Fc binding protein
US5882896A (en) 1996-09-24 1999-03-16 Smithkline Beecham Corporation M protein
US20100267012A1 (en) 1997-11-04 2010-10-21 Bergeron Michel G Highly conserved genes and their use to generate probes and primers for detection of microorganisms
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EP1019522A4 (en) * 1996-12-04 2002-06-19 Univ Alabama CONNECTIONS AND METHODS FOR ADMINISTERING PNEUMOCOCCAL DNA
KR19980067137A (ko) * 1997-01-31 1998-10-15 박원훈 알긴산염 초미세과립구를 이용한 폐렴구균 감연중에 대한 백신
EP1015591A2 (en) * 1997-09-18 2000-07-05 Pasteur Mérieux Connaught Improved method of production of pneumococcal surface proteins
US6224882B1 (en) 1997-11-07 2001-05-01 Protein Science Corp. Insect cells or fractions as adjuvant for antigens
US20010016200A1 (en) * 1998-04-23 2001-08-23 Briles David E. Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
CA2388461C (en) 1999-09-28 2013-06-11 Infectio Diagnostic (I.D.I.) Inc. Highly conserved genes and their use to generate probes and primers for the detection of microorganisms
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AT410412B (de) 2000-11-10 2003-04-25 Inteco Int Techn Beratung Verfahren zum elektroschlacke umschmelzen von metallen
US8691243B2 (en) 2002-04-02 2014-04-08 Ben-Gurion University Of The Negev Research And Development Authority Protein-based Streptococcus pneumoniae vaccine
IL164242A0 (en) * 2002-04-02 2005-12-18 Univ Ben Gurion Protein-based streptococcus pneumoniae vaccines
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
DK3017827T3 (en) 2005-12-22 2019-02-18 Glaxosmithkline Biologicals Sa Pneumococcal polysaccharide conjugate VACCINE
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
KR20080096775A (ko) 2006-01-17 2008-11-03 아르네 포르스그렌 표면 노출된 헤모필루스 인플루엔자 단백질 （단백질 Ｅ ―ｐＥ）
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KR20110009157A (ko) 2008-04-16 2011-01-27 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신
JP5721620B2 (ja) 2008-05-02 2015-05-20 キャンサー・リサーチ・テクノロジー・リミテッドＣａｎｃｅｒ Ｒｅｓｅａｒｃｈ Ｔｅｃｈｎｏｌｏｇｙ Ｌｉｍｉｔｅｄ 免疫応答を刺激するための作製物および方法
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CN110381992A (zh) * 2016-12-03 2019-10-25 Uab研究基金会 组合了肺炎球菌表面蛋白A的选择的α螺旋结构域和脯氨酸富集结构域的肺炎球菌疫苗
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
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Also Published As

Publication number Publication date
US5728387A (en) 1998-03-17
AU667668B2 (en) 1996-04-04
DE69226167T2 (de) 1998-11-12
DK0571538T5 (da) 2002-03-04
FI933580A (fi) 1993-10-13
ATE168132T1 (de) 1998-07-15
NO313999B1 (no) 2003-01-13
JP2001204482A (ja) 2001-07-31
AU692678B2 (en) 1998-06-11
EP0571538A1 (en) 1993-12-01
CA2104014A1 (en) 1992-08-16
AU692678C (en) 2002-08-29
ES2118812T3 (es) 1998-10-01
IE20000062A1 (en) 2000-12-13
DK0571538T3 (da) 1999-04-19
AU4798096A (en) 1996-06-27
EP0571538B1 (en) 1998-07-08
AU1445392A (en) 1992-09-15
ZA921025B (en) 1992-11-25
NO932890L (no) 1993-10-14
IE920479A1 (en) 1992-08-26
NO932890D0 (no) 1993-08-13
JP3215109B2 (ja) 2001-10-02
IL100946A0 (en) 1992-11-15
DE69226167D1 (de) 1998-08-13
JPH06504446A (ja) 1994-05-26
JPH09224680A (ja) 1997-09-02
WO1992014488A1 (en) 1992-09-03
EP0786521A1 (en) 1997-07-30
FI933580A0 (fi) 1993-08-13
EP0571538A4 (en) 1994-08-24
CA2104014C (en) 2000-05-02

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Legal Events

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PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20050212