HK1004570A1 - Recombinant dna molecules encoding for hepatitis b surface antigen, their preparation and derived vaccines - Google Patents

Recombinant dna molecules encoding for hepatitis b surface antigen, their preparation and derived vaccines Download PDF

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Publication number
HK1004570A1
HK1004570A1 HK98103620A HK98103620A HK1004570A1 HK 1004570 A1 HK1004570 A1 HK 1004570A1 HK 98103620 A HK98103620 A HK 98103620A HK 98103620 A HK98103620 A HK 98103620A HK 1004570 A1 HK1004570 A1 HK 1004570A1
Authority
HK
Hong Kong
Prior art keywords
hbsag
polypeptide
region
dna
derived
Prior art date
Application number
HK98103620A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1004570B (en
Inventor
Cabezon Theresa
Crabeel Marjolene
De Wilde Michel
Harford Nigel
Original Assignee
Smithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Biologicals S.A. filed Critical Smithkline Biologicals S.A.
Publication of HK1004570B publication Critical patent/HK1004570B/xx
Publication of HK1004570A1 publication Critical patent/HK1004570A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK98103620A 1982-09-08 1998-04-28 Recombinant dna molecules encoding for hepatitis b surface antigen, their preparation and derived vaccines HK1004570A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41578982A 1982-09-08 1982-09-08
US415789 1982-09-08

Publications (2)

Publication Number Publication Date
HK1004570B HK1004570B (en) 1998-11-27
HK1004570A1 true HK1004570A1 (en) 1998-11-27

Family

ID=23647197

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98103620A HK1004570A1 (en) 1982-09-08 1998-04-28 Recombinant dna molecules encoding for hepatitis b surface antigen, their preparation and derived vaccines

Country Status (22)

Country Link
EP (1) EP0106828B1 (OSRAM)
JP (5) JPS5971694A (OSRAM)
KR (1) KR840006014A (OSRAM)
AT (1) ATE91718T1 (OSRAM)
AU (4) AU584580B2 (OSRAM)
CA (1) CA1222707A (OSRAM)
CY (1) CY1932A (OSRAM)
DE (1) DE3382704T2 (OSRAM)
DK (1) DK406483A (OSRAM)
ES (4) ES8506350A1 (OSRAM)
FI (1) FI833205A7 (OSRAM)
GR (1) GR78982B (OSRAM)
HK (1) HK1004570A1 (OSRAM)
HU (1) HU196625B (OSRAM)
IE (1) IE60387B1 (OSRAM)
IL (1) IL69202A (OSRAM)
MA (1) MA19895A1 (OSRAM)
MY (1) MY102920A (OSRAM)
NO (1) NO833198L (OSRAM)
NZ (1) NZ204952A (OSRAM)
PT (1) PT77265B (OSRAM)
ZA (1) ZA836658B (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936699A (ja) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst シヤトルベクタ−
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
WO1986001534A1 (fr) * 1984-09-04 1986-03-13 Takeda Chemical Industries, Ltd. Adn recombinant et son utilisation
WO1986007384A1 (fr) * 1985-06-03 1986-12-18 Takeda Chemical Industries, Ltd. Procede de preparation de l'antigene p31 de surface du virus de l'hepatite b
WO1986003411A1 (fr) * 1984-12-12 1986-06-19 Takeda Chemical Industries, Ltd. Procede de preparation d'une nouvelle proteine
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
DE3677851D1 (de) * 1985-08-05 1991-04-11 Merck & Co Inc Verfahren zur steigerung der produktion von rekombinantem protein in hefearten der gattung saccharomyces.
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
ZA88488B (en) * 1987-01-30 1988-10-26 Smith Kline Rit Hepatitis b virus surface antigens and hybrid antigens containing them
ATE93891T1 (de) * 1987-03-09 1993-09-15 Merck & Co Inc Reinigung von rekombiniertem hepatitis-boberfl|chen-antigen.
NZ229260A (en) * 1988-06-03 1994-02-25 Merck & Co Inc Hepatitis b virus, expression cassette for pre-s domain, host cells and
US4962656A (en) * 1989-06-30 1990-10-16 The United States Of America As Represented By The United States Department Of Energy Control and monitoring method and system for electromagnetic forming process
LT3988B (en) 1992-02-17 1996-06-25 Fermentas Biotech Inst Recombinant plasmides pfs19, pfps2-48 and pjlfds1 codingsynthesis of human hepatite b of surfice virus antigenes, methods fof producing thereof
TW340132B (en) * 1994-10-20 1998-09-11 Ibm Structure for use as an electrical interconnection means and process for preparing the same
JP4028850B2 (ja) * 2004-02-04 2007-12-26 株式会社名機製作所 ディスク基板の成形用金型

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI86437C (fi) * 1978-12-22 1992-08-25 Biogen Inc Foerfarande foer framstaellning av polypeptider med de antigena egenskaperna hos ett hepatitis b- virusantigen.
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
GR76274B (OSRAM) * 1981-08-04 1984-08-04 Univ California
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides

Also Published As

Publication number Publication date
JPH02116A (ja) 1990-01-05
MA19895A1 (fr) 1984-04-01
ES8600938A1 (es) 1985-10-16
DK406483A (da) 1984-03-09
JPS5971694A (ja) 1984-04-23
PT77265B (en) 1986-02-04
GR78982B (OSRAM) 1984-10-02
JPH08317796A (ja) 1996-12-03
FI833205L (fi) 1984-03-09
FI833205A7 (fi) 1984-03-09
ES8600939A1 (es) 1985-10-16
JPH02464A (ja) 1990-01-05
FI833205A0 (fi) 1983-09-07
KR840006014A (ko) 1984-11-21
ES8602120A1 (es) 1985-11-01
EP0106828A2 (fr) 1984-04-25
AU9001491A (en) 1992-02-27
ATE91718T1 (de) 1993-08-15
ES532731A0 (es) 1985-11-01
ES532730A0 (es) 1985-10-16
CY1932A (en) 1983-09-06
ZA836658B (en) 1984-06-27
HU196625B (en) 1988-12-28
ES525439A0 (es) 1985-07-01
EP0106828B1 (fr) 1993-07-21
AU3131889A (en) 1989-07-20
JP2522825B2 (ja) 1996-08-07
DE3382704T2 (de) 1994-02-10
NZ204952A (en) 1986-05-09
DE3382704D1 (de) 1993-08-26
CA1222707A (en) 1987-06-09
ES8506350A1 (es) 1985-07-01
ES532732A0 (es) 1985-10-16
AU1569288A (en) 1988-07-28
AU1675083A (en) 1984-03-15
IE832099L (en) 1984-03-08
EP0106828A3 (en) 1985-11-21
IE60387B1 (en) 1994-07-13
NO833198L (no) 1984-03-09
IL69202A (en) 1991-08-16
DK406483D0 (da) 1983-09-07
JPH02231084A (ja) 1990-09-13
MY102920A (en) 1993-03-31
PT77265A (en) 1983-09-01
JP2702899B2 (ja) 1998-01-26
AU584580B2 (en) 1989-06-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)