HK1004336A1 - Isolation and purification of lung surfactant protein - Google Patents

Isolation and purification of lung surfactant protein Download PDF

Info

Publication number
HK1004336A1
HK1004336A1 HK98103063A HK98103063A HK1004336A1 HK 1004336 A1 HK1004336 A1 HK 1004336A1 HK 98103063 A HK98103063 A HK 98103063A HK 98103063 A HK98103063 A HK 98103063A HK 1004336 A1 HK1004336 A1 HK 1004336A1
Authority
HK
Hong Kong
Prior art keywords
rsp
process according
inclusion bodies
fusion protein
aliphatic alcohol
Prior art date
Application number
HK98103063A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1004336B (en
Inventor
J. Benson Bradley
Buckley Douglas
Lesikar David
Naidu Asha
Baptie Silverness Katie
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of HK1004336B publication Critical patent/HK1004336B/en
Publication of HK1004336A1 publication Critical patent/HK1004336A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785Alveolar surfactant peptides; Pulmonary surfactant peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/848Lungs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK98103063A 1990-07-10 1991-07-10 Isolation and purification of lung surfactant protein HK1004336A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US551524 1983-11-14
US07/551,524 US5258496A (en) 1990-07-10 1990-07-10 Isolation and purification of lung surfactant protein
PCT/US1991/004890 WO1992000993A1 (en) 1990-07-10 1991-07-10 Isolation and purification of lung surfactant protein

Publications (2)

Publication Number Publication Date
HK1004336B HK1004336B (en) 1998-11-20
HK1004336A1 true HK1004336A1 (en) 1998-11-20

Family

ID=24201618

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98103063A HK1004336A1 (en) 1990-07-10 1991-07-10 Isolation and purification of lung surfactant protein

Country Status (11)

Country Link
US (2) US5258496A (enExample)
EP (1) EP0491033B1 (enExample)
JP (1) JP3056525B2 (enExample)
AT (1) ATE159534T1 (enExample)
CA (1) CA2065323C (enExample)
DE (1) DE69128022T2 (enExample)
DK (1) DK0491033T3 (enExample)
ES (1) ES2111570T3 (enExample)
GR (1) GR3025929T3 (enExample)
HK (1) HK1004336A1 (enExample)
WO (1) WO1992000993A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE911129A1 (en) * 1990-04-04 1991-10-09 Chiron Corp Hepatitis c virus protease
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
ATE163426T1 (de) * 1993-04-30 1998-03-15 Tokyo Tanabe Co Verfahren zur reinigung eines hydrophoben polypeptides
AU700605B2 (en) * 1994-12-07 1999-01-07 Bionebraska, Inc. Production of peptides using recombinant fusion protein constructs
WO1996017941A2 (en) * 1994-12-07 1996-06-13 Bionebraska, Inc. Production of c-terminal amidated peptides from recombinant protein constructs
US6031075A (en) * 1996-02-05 2000-02-29 Children's Hospital Medical Center Mature alveolar SP-B and a process for producing the same
WO1997041155A2 (en) * 1996-04-26 1997-11-06 Ony, Inc. Compositions and methods for isolating lung surfactant hydrophobic proteins sp-b and sp-c
US6020307A (en) * 1997-04-25 2000-02-01 Ony, Inc. Compositions and methods for isolating lung surfactant hydrophobic proteins SP-B and SP-C
ATE301674T1 (de) * 1996-05-15 2005-08-15 Altana Pharma Ag Verfahren zur trennung und bestimmung von hydrophoben proteinen durch dünnschichtchromatographie
AU1938599A (en) * 1997-12-23 1999-07-12 Eli Lilly And Company Beta-lipotropin and uses thereof
JPH11335392A (ja) 1998-05-26 1999-12-07 Hsp Kenkyusho:Kk 可溶性タンパク質の回収方法
WO2008122089A1 (en) * 2007-04-05 2008-10-16 The University Of Queensland Method of purifying recombinant peptides by selective precipitation
WO2009035395A1 (en) 2007-09-14 2009-03-19 Marcus Larsson A lung-surfactant product

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4882422A (en) * 1985-10-24 1989-11-21 Genetics Institute, Inc. Pulmonary surfactant proteins
US4918161A (en) * 1985-09-26 1990-04-17 Genetics Institute, Inc. Low molecular weight pulmonary surfactant proteins
EP0240550A4 (en) * 1985-09-26 1989-09-19 Genetics Inst TENSIO-ACTIVE PULMONARY PROTEINS.
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
JPS63503222A (ja) * 1986-05-06 1988-11-24 サイオス ノバ インコーポレイテッド 肺の疎水性界面活性物質に結合した分子量6,000ダルトンのタンパク質及びその多量体
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト,ジエフリー エイ. 肺胞疎水性界面活性物質関連タンパク質
WO1988005820A1 (en) * 1987-01-29 1988-08-11 California Biotechnology, Inc. Recombinant alveolar surfactant protein
AU622860B2 (en) * 1987-05-11 1992-04-30 Novartis Vaccines And Diagnostics, Inc. Process for recovering purified, oxidized, renatured recombinant interleukin-2 from microorganisms
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
KR960010558B1 (ko) * 1987-11-04 1996-08-02 캘리포니아 바이오테크놀로지 인코오퍼레이티드 폐포계면활성 단백질
EP0320126A1 (en) * 1987-11-12 1989-06-14 Unilever Plc Stability of liquid automatic dish-washing detergents
CH677879A5 (enExample) * 1988-07-22 1991-07-15 Pentapharm Ag
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
EP0482097B1 (en) * 1989-07-11 2001-06-06 Genentech, Inc. Surfactant compositions and methods
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein

Also Published As

Publication number Publication date
DE69128022D1 (de) 1997-11-27
CA2065323A1 (en) 1992-01-11
GR3025929T3 (en) 1998-04-30
DK0491033T3 (da) 1998-07-20
JPH05502888A (ja) 1993-05-20
ATE159534T1 (de) 1997-11-15
EP0491033A1 (en) 1992-06-24
CA2065323C (en) 2003-06-10
EP0491033A4 (enExample) 1994-03-30
JP3056525B2 (ja) 2000-06-26
WO1992000993A1 (en) 1992-01-23
EP0491033B1 (en) 1997-10-22
US5258496A (en) 1993-11-02
US5403915A (en) 1995-04-04
DE69128022T2 (de) 1998-05-20
ES2111570T3 (es) 1998-03-16

Similar Documents

Publication Publication Date Title
US5874406A (en) Synthetic peptide analogs of lung surface protein SP-C
EP0491033B1 (en) Isolation and purification of lung surfactant protein
KR101098897B1 (ko) 원핵생물 숙주 내 il-21 생산
US20100210815A1 (en) Insulin production methods and pro-insulin constructs
HK1004336B (en) Isolation and purification of lung surfactant protein
JPH08228791A (ja) ストレプトアビジン様ポリペプチドの製造
JP2602968B2 (ja) 肺胞の界面活性タンパク類
JPH0771483B2 (ja) 高収量の組換え産物の産生宿主体
US20060172384A1 (en) FGF18 production in prokaryotic hosts
EP0338634A2 (en) Viper venom polypeptides and genetic expression
JP2010031055A (ja) Tfpiおよびtfpiアナログを精製するための改良された方法
JP2002332298A (ja) 肺胞界面活性タンパク質
JPS6299399A (ja) ヒトγ−インタ−フエロンの生物活性誘導体
JP2517100B2 (ja) ヒト顆粒球コロニ―刺激因子活性を有する蛋白質の精製法
CA2016018A1 (en) Purification of proteins employing ctap-iii fusions
EP0437367A2 (en) Compositions and methods for inhibiting osteoclast cellular adhesion to bone
JPS62175192A (ja) ヒトインスリン様成長因子1の製造法
Borjigin et al. Bovine pancreatic trypsin inhibitor-trypsin complex as a detection system for recombinant proteins.
JPH0680697A (ja) ヒト好中球エラスターゼ阻害活性を有する天然型ポリペプチドおよびそれを含有する医薬製剤
JPH0330693A (ja) 新規生理活性ポリペプチド
JP2560969B2 (ja) ヒトインスリン様成長因子i遺伝子
ZA200505101B (en) IL-21 production in prokaryotic hosts
JPH03259092A (ja) 蛋白質の製造法
HK1000891B (en) Synthetic peptide analogs of lung surfactant protein sp-c
JPS63226298A (ja) 新規生理活性ポリペプチド

Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20110709