ATE159534T1 - Isolierung und reinigung eines oberflächenaktiven proteins aus lunge - Google Patents

Isolierung und reinigung eines oberflächenaktiven proteins aus lunge

Info

Publication number
ATE159534T1
ATE159534T1 AT91913203T AT91913203T ATE159534T1 AT E159534 T1 ATE159534 T1 AT E159534T1 AT 91913203 T AT91913203 T AT 91913203T AT 91913203 T AT91913203 T AT 91913203T AT E159534 T1 ATE159534 T1 AT E159534T1
Authority
AT
Austria
Prior art keywords
isolation
purification
lung
active protein
aliphatic alcohol
Prior art date
Application number
AT91913203T
Other languages
German (de)
English (en)
Inventor
Bradley J Benson
Douglas Buckley
David Lesikar
Asha Naidu
Katie Baptie Silverness
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Application granted granted Critical
Publication of ATE159534T1 publication Critical patent/ATE159534T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/848—Lungs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT91913203T 1990-07-10 1991-07-10 Isolierung und reinigung eines oberflächenaktiven proteins aus lunge ATE159534T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/551,524 US5258496A (en) 1990-07-10 1990-07-10 Isolation and purification of lung surfactant protein

Publications (1)

Publication Number Publication Date
ATE159534T1 true ATE159534T1 (de) 1997-11-15

Family

ID=24201618

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91913203T ATE159534T1 (de) 1990-07-10 1991-07-10 Isolierung und reinigung eines oberflächenaktiven proteins aus lunge

Country Status (10)

Country Link
US (2) US5258496A (enExample)
EP (1) EP0491033B1 (enExample)
JP (1) JP3056525B2 (enExample)
AT (1) ATE159534T1 (enExample)
CA (1) CA2065323C (enExample)
DE (1) DE69128022T2 (enExample)
DK (1) DK0491033T3 (enExample)
ES (1) ES2111570T3 (enExample)
GR (1) GR3025929T3 (enExample)
WO (1) WO1992000993A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL169273B1 (pl) * 1990-04-04 1996-06-28 Chiron Corp skierowanej przeciw wirusowi zapalenia watroby C PL
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
ES2113101T3 (es) * 1993-04-30 1998-04-16 Tokyo Tanabe Co Metodo para purificar polipeptidos hidrofobos.
CA2206848A1 (en) * 1994-12-07 1996-06-13 Bionebraska, Inc. Production of peptides using recombinant fusion protein constructs
AU4415796A (en) * 1994-12-07 1996-06-26 Bionebraska, Inc. Production of c-terminal amidated peptides from recombinant protein constructs
US6031075A (en) * 1996-02-05 2000-02-29 Children's Hospital Medical Center Mature alveolar SP-B and a process for producing the same
US6020307A (en) * 1997-04-25 2000-02-01 Ony, Inc. Compositions and methods for isolating lung surfactant hydrophobic proteins SP-B and SP-C
WO1997041155A2 (en) * 1996-04-26 1997-11-06 Ony, Inc. Compositions and methods for isolating lung surfactant hydrophobic proteins sp-b and sp-c
JP4181216B2 (ja) * 1996-05-15 2008-11-12 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 薄層クロマトグラフィーを用いる疎水性蛋白質の分離及び分析法
AR018532A1 (es) * 1997-12-23 2001-11-28 Lilly Co Eli Proteinas sustancialmente puras que contienen analogos de la beta-lipoproteina (blt); aislados de acidos nucleicos que codifican dichas proteinas yformulaciones farmaceuticas que comprenden las proteinas
JPH11335392A (ja) * 1998-05-26 1999-12-07 Hsp Kenkyusho:Kk 可溶性タンパク質の回収方法
WO2008122089A1 (en) * 2007-04-05 2008-10-16 The University Of Queensland Method of purifying recombinant peptides by selective precipitation
EP2197459B1 (en) * 2007-09-14 2016-01-06 Marcus Larsson A lung-surfactant product

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240550A4 (en) * 1985-09-26 1989-09-19 Genetics Inst TENSIO-ACTIVE PULMONARY PROTEINS.
US4918161A (en) * 1985-09-26 1990-04-17 Genetics Institute, Inc. Low molecular weight pulmonary surfactant proteins
US4882422A (en) * 1985-10-24 1989-11-21 Genetics Institute, Inc. Pulmonary surfactant proteins
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
JPS63503222A (ja) * 1986-05-06 1988-11-24 サイオス　ノバ　インコーポレイテッド 肺の疎水性界面活性物質に結合した分子量６，０００ダルトンのタンパク質及びその多量体
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト，ジエフリー　エイ． 肺胞疎水性界面活性物質関連タンパク質
WO1988005820A1 (en) * 1987-01-29 1988-08-11 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
AU622860B2 (en) * 1987-05-11 1992-04-30 Novartis Vaccines And Diagnostics, Inc. Process for recovering purified, oxidized, renatured recombinant interleukin-2 from microorganisms
WO1989004326A1 (en) * 1987-11-04 1989-05-18 California Biotechnology Inc. Alveolar surfactant proteins
WO1989004362A1 (en) * 1987-11-12 1989-05-18 Unilever Plc Improved physical stability of liquid automatic dishwashing detergent
CH677879A5 (enExample) * 1988-07-22 1991-07-15 Pentapharm Ag
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
WO1991000871A1 (en) * 1989-07-11 1991-01-24 Genentech, Inc. Surfactant compositions and methods
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein

Also Published As

Publication number Publication date
CA2065323A1 (en) 1992-01-11
EP0491033B1 (en) 1997-10-22
US5403915A (en) 1995-04-04
WO1992000993A1 (en) 1992-01-23
DE69128022T2 (de) 1998-05-20
DE69128022D1 (de) 1997-11-27
ES2111570T3 (es) 1998-03-16
GR3025929T3 (en) 1998-04-30
EP0491033A4 (enExample) 1994-03-30
JP3056525B2 (ja) 2000-06-26
HK1004336A1 (en) 1998-11-20
DK0491033T3 (da) 1998-07-20
CA2065323C (en) 2003-06-10
US5258496A (en) 1993-11-02
JPH05502888A (ja) 1993-05-20
EP0491033A1 (en) 1992-06-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEFA Change of the company name
EELA Cancelled due to lapse of time