GT199900006A - Nuevos pentasacaridos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Nuevos pentasacaridos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
GT199900006A
GT199900006A GT199900006A GT199900006A GT199900006A GT 199900006 A GT199900006 A GT 199900006A GT 199900006 A GT199900006 A GT 199900006A GT 199900006 A GT199900006 A GT 199900006A GT 199900006 A GT199900006 A GT 199900006A
Authority
GT
Guatemala
Prior art keywords
pentacarides
procedure
contain
preparation
new
Prior art date
Application number
GT199900006A
Other languages
English (en)
Spanish (es)
Inventor
Maurice Petitou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT199900006A publication Critical patent/GT199900006A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GT199900006A 1998-01-19 1999-01-19 Nuevos pentasacaridos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. GT199900006A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9800514A FR2773801B1 (fr) 1998-01-19 1998-01-19 Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
GT199900006A true GT199900006A (es) 2000-07-12

Family

ID=9521913

Family Applications (1)

Application Number Title Priority Date Filing Date
GT199900006A GT199900006A (es) 1998-01-19 1999-01-19 Nuevos pentasacaridos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Country Status (38)

Country Link
US (1) US6670338B1 (enExample)
EP (1) EP1049706B1 (enExample)
JP (1) JP4695756B2 (enExample)
KR (1) KR100533565B1 (enExample)
CN (1) CN1172948C (enExample)
AR (1) AR012779A1 (enExample)
AT (1) ATE241637T1 (enExample)
AU (1) AU744137B2 (enExample)
BR (1) BR9907100B1 (enExample)
CA (1) CA2318326C (enExample)
CO (1) CO4970823A1 (enExample)
CZ (1) CZ299817B6 (enExample)
DE (1) DE69908298T2 (enExample)
DK (1) DK1049706T3 (enExample)
DZ (1) DZ2706A1 (enExample)
EE (1) EE04194B1 (enExample)
EG (1) EG23760A (enExample)
ES (1) ES2200494T3 (enExample)
FR (1) FR2773801B1 (enExample)
GT (1) GT199900006A (enExample)
HR (1) HRP20000479A8 (enExample)
HU (1) HU228335B1 (enExample)
IL (2) IL137240A0 (enExample)
MY (1) MY125636A (enExample)
NO (1) NO316894B1 (enExample)
NZ (1) NZ505614A (enExample)
PL (1) PL191098B1 (enExample)
PT (1) PT1049706E (enExample)
RU (1) RU2193040C2 (enExample)
SA (1) SA99191114B1 (enExample)
SI (1) SI1049706T1 (enExample)
SK (1) SK284176B6 (enExample)
TR (1) TR200002077T2 (enExample)
TW (1) TW550267B (enExample)
UA (1) UA61124C2 (enExample)
UY (1) UY25357A1 (enExample)
WO (1) WO1999036428A1 (enExample)
ZA (1) ZA99357B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
CN100513398C (zh) 2002-12-03 2009-07-15 Axys药物公司 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物
KR101156273B1 (ko) * 2004-03-04 2012-06-13 프로젠 파마슈티칼즈 리미티드 황산화 올리고사카라이드 유도체
CN100338084C (zh) * 2004-07-02 2007-09-19 北京大学 抑制异种器官移植免疫排斥反应的五糖抗原的合成方法
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
US20070191306A1 (en) * 2005-08-17 2007-08-16 Bristol-Myers Squibb Company FACTOR Xa INHIBITOR FORMULATION AND METHOD
EP1908768A1 (en) * 2006-10-05 2008-04-09 Endotis Pharma Anticoagulant compounds
CN102046781A (zh) 2008-05-30 2011-05-04 动量制药公司 糖结构以及制造和使用此类结构的方法
WO2010029552A1 (en) * 2008-09-10 2010-03-18 Transpharma Medical Ltd. Transdermal delivery of oligosaccharides
WO2011014793A2 (en) * 2009-07-31 2011-02-03 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
CN103917552B (zh) * 2011-06-17 2017-03-29 卡博梅麦特斯公司 具有短半衰期和高活性的合成五糖

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
DK0454220T3 (da) * 1990-04-23 1993-11-22 Sanofi Elf Carbohydratderivater omfattende en trisaccharidenhed
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
ES2147216T3 (es) * 1993-09-01 2000-09-01 Akzo Nobel Nv Bisconjugados que comprenden dos sacaridos y un grupo de union.
FR2751334B1 (fr) * 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
CA2318326A1 (en) 1999-07-22
IL137240A0 (en) 2001-07-24
UA61124C2 (en) 2003-11-17
SI1049706T1 (en) 2003-12-31
ES2200494T3 (es) 2004-03-01
RU2193040C2 (ru) 2002-11-20
EE200000421A1 (et) 2003-06-16
CN1172948C (zh) 2004-10-27
PL191098B1 (pl) 2006-03-31
HUP0102042A1 (hu) 2001-10-28
EP1049706B1 (fr) 2003-05-28
HUP0102042A3 (en) 2003-07-28
HU228335B1 (en) 2013-03-28
AU1974699A (en) 1999-08-02
DZ2706A1 (fr) 2003-09-01
DE69908298T2 (de) 2004-04-01
NZ505614A (en) 2003-02-28
FR2773801B1 (fr) 2000-05-12
PL341874A1 (en) 2001-05-07
IL137240A (en) 2007-10-31
NO316894B1 (no) 2004-06-14
JP4695756B2 (ja) 2011-06-08
EE04194B1 (et) 2003-12-15
ZA99357B (en) 2000-07-19
MY125636A (en) 2006-08-30
US6670338B1 (en) 2003-12-30
DE69908298D1 (de) 2003-07-03
HRP20000479A2 (en) 2001-02-28
PT1049706E (pt) 2003-09-30
KR100533565B1 (ko) 2005-12-06
AU744137B2 (en) 2002-02-14
ATE241637T1 (de) 2003-06-15
HRP20000479B8 (hr) 2025-09-12
TW550267B (en) 2003-09-01
CO4970823A1 (es) 2000-11-07
AR012779A1 (es) 2000-11-08
CA2318326C (en) 2010-07-06
SK284176B6 (sk) 2004-10-05
EP1049706A1 (fr) 2000-11-08
FR2773801A1 (fr) 1999-07-23
CN1293679A (zh) 2001-05-02
CZ20002636A3 (cs) 2000-11-15
NO20003661L (no) 2000-09-19
UY25357A1 (es) 2000-12-29
BR9907100B1 (pt) 2013-09-03
SA99191114B1 (ar) 2006-10-11
JP2002509154A (ja) 2002-03-26
KR20010034205A (ko) 2001-04-25
HRP20000479A8 (hr) 2025-09-12
NO20003661D0 (no) 2000-07-17
WO1999036428A1 (fr) 1999-07-22
DK1049706T3 (da) 2003-09-29
HK1029999A1 (zh) 2001-04-20
TR200002077T2 (tr) 2000-12-21
SK10792000A3 (sk) 2001-01-18
CZ299817B6 (cs) 2008-12-03
EE200000421A (et) 2001-12-17
BR9907100A (pt) 2000-10-24
HRP20000479B1 (hr) 2006-04-30
EG23760A (en) 2007-08-08

Similar Documents

Publication Publication Date Title
AR013494A1 (es) Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen
ES2097409T3 (es) Benzoilguanidinas, procedimiento para su preparacion, asi como su empleo como antiarritmicos.
ES2118095T3 (es) Bencimidazoles, medicamentos que contienen estos compuestos y procedimiento para su preparacion.
ES2117155T3 (es) Nuevas 3,3-difenilpropilaminas, su uso y su preparacion.
DK0925303T3 (da) Phosphinsyreamider som matrixmetalloproteaseinhibitorer
ES2100907T3 (es) Bencimidazoles, medicamentos que contienen estos compuestos y proced imiento para su preparacion.
EP1031573A4 (en) BENZOYLPYRAZOLE COMPOUNDS, INTERMEDIATE PRODUCTS AND HERBICIDES
UY25357A1 (es) Nuevos pentasacáridos, procedimiento para su preparación y composiciones farmacéuticas que los contienen.
ES8304070A1 (es) "procedimiento para la preparacion de nuevas amidas de acidos carboxilicos".
AR030537A1 (es) Acidos quinolincarboxilicos y naftiridincarboxilico antibacterianos
FI964045A0 (fi) CCK:ta tai gastriinia säätelevä 5-heterosykli-1,5-bentsodiatsepiinejä
BR9814495A (pt) Composto, processo para prepará-lo, uso do mesmo, composição farmacêutica, e, processo
AR021268A1 (es) Proceso para preparar compuestos acilaromaticos
ES2093286T3 (es) Bencimidazoles, medicamentos que contienen estos compuestos y procedimiento para su preparacion.
BR0115616A (pt) Preparação de inibidores de permutadores sódio-hidrogênio do tipo 1
ES2182090T3 (es) Nuevos derivados de pirrol.
ES2176723T3 (es) Composiciones para el tinte de las fibras queratinicas que contienen pirazolin-3,5-diona, su utilizacion como copuladores para el tinte y metodo de tinte.
CO4950550A1 (es) Procedimiento
ES2189736T3 (es) Derivados de la benzamida y medicamentos que los contienen.
AR035489A1 (es) 4-fenil-1-(1-fenil-ciclohexil)-1,2,3,6,-tetrahidropiridinas sustituidas, procedimientos para su preparacion, medicamentos que contienen estos compuestos y el uso de estas sustancias para la preparacion de medicamentos
PA8513301A1 (es) Inhibidor del intercambiador de sodio-hidrògeno de tipo 1
ES2162086T3 (es) Diamidas acidas aromaticas con actividad antigastrina, un metodo para su preparacion y su uso farmaceutico.
AR027446A1 (es) Enaminomas heterociclicas fenil-sustituidas
ES2115543B1 (es) Procedimiento para la obtencion de carbetocina y sus sales de adicion de acido farmaceuticamente aceptables o complejos de la misma.
ES2000458A6 (es) Procedimiento para la obtencion de nuevos tieno-1,2-tiazolderivados y sales farmaceuticamente aceptables de los mismos