TR200002077T2 - Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar. - Google Patents

Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar.

Info

Publication number
TR200002077T2
TR200002077T2 TR2000/02077T TR200002077T TR200002077T2 TR 200002077 T2 TR200002077 T2 TR 200002077T2 TR 2000/02077 T TR2000/02077 T TR 2000/02077T TR 200002077 T TR200002077 T TR 200002077T TR 200002077 T2 TR200002077 T2 TR 200002077T2
Authority
TR
Turkey
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
pentasaccharides
Prior art date
Application number
TR2000/02077T
Other languages
English (en)
Turkish (tr)
Inventor
Petitou Maurice
Original Assignee
Sanofi-Synthelabo
Akzo Nobell N..V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo, Akzo Nobell N..V. filed Critical Sanofi-Synthelabo
Publication of TR200002077T2 publication Critical patent/TR200002077T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TR2000/02077T 1998-01-19 1999-01-13 Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar. TR200002077T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9800514A FR2773801B1 (fr) 1998-01-19 1998-01-19 Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
TR200002077T2 true TR200002077T2 (tr) 2000-12-21

Family

ID=9521913

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02077T TR200002077T2 (tr) 1998-01-19 1999-01-13 Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar.

Country Status (38)

Country Link
US (1) US6670338B1 (enExample)
EP (1) EP1049706B1 (enExample)
JP (1) JP4695756B2 (enExample)
KR (1) KR100533565B1 (enExample)
CN (1) CN1172948C (enExample)
AR (1) AR012779A1 (enExample)
AT (1) ATE241637T1 (enExample)
AU (1) AU744137B2 (enExample)
BR (1) BR9907100B1 (enExample)
CA (1) CA2318326C (enExample)
CO (1) CO4970823A1 (enExample)
CZ (1) CZ299817B6 (enExample)
DE (1) DE69908298T2 (enExample)
DK (1) DK1049706T3 (enExample)
DZ (1) DZ2706A1 (enExample)
EE (1) EE04194B1 (enExample)
EG (1) EG23760A (enExample)
ES (1) ES2200494T3 (enExample)
FR (1) FR2773801B1 (enExample)
GT (1) GT199900006A (enExample)
HR (1) HRP20000479B8 (enExample)
HU (1) HU228335B1 (enExample)
IL (2) IL137240A0 (enExample)
MY (1) MY125636A (enExample)
NO (1) NO316894B1 (enExample)
NZ (1) NZ505614A (enExample)
PL (1) PL191098B1 (enExample)
PT (1) PT1049706E (enExample)
RU (1) RU2193040C2 (enExample)
SA (1) SA99191114B1 (enExample)
SI (1) SI1049706T1 (enExample)
SK (1) SK284176B6 (enExample)
TR (1) TR200002077T2 (enExample)
TW (1) TW550267B (enExample)
UA (1) UA61124C2 (enExample)
UY (1) UY25357A1 (enExample)
WO (1) WO1999036428A1 (enExample)
ZA (1) ZA99357B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
PT1569912E (pt) 2002-12-03 2015-09-15 Pharmacyclics Llc Derivados 2-(2-hidroxibifenil-3-il)-1h-benzoimidazole-5- carboxamidina como inibidores do fator viia
AU2005219456B2 (en) * 2004-03-04 2011-04-07 Progen Pharmaceuticals Limited Sulfated oligosaccharide derivatives
CN100338084C (zh) * 2004-07-02 2007-09-19 北京大学 抑制异种器官移植免疫排斥反应的五糖抗原的合成方法
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
US20070191306A1 (en) * 2005-08-17 2007-08-16 Bristol-Myers Squibb Company FACTOR Xa INHIBITOR FORMULATION AND METHOD
EP1908768A1 (en) * 2006-10-05 2008-04-09 Endotis Pharma Anticoagulant compounds
AU2009260434B2 (en) 2008-05-30 2014-03-06 Momenta Pharmaceuticals, Inc. Saccharide structures and methods of making and using such structures
EP2323605A4 (en) * 2008-09-10 2014-02-05 Syneron Medical Ltd TRANSDERMAL RELEASE OF OLIGOSACCHARIDES
EP3666786A1 (en) * 2009-07-31 2020-06-17 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
CA2839139A1 (en) * 2011-06-17 2012-12-20 Carbomimetics Synthetic pentasaccharides having short half-life and high activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
DK0454220T3 (da) * 1990-04-23 1993-11-22 Sanofi Elf Carbohydratderivater omfattende en trisaccharidenhed
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
NZ264340A (en) * 1993-09-01 1995-04-27 Akzo Nobel Nv Bisconjugate comprising two saccharides and a spacer, use in pharmaceutical compositions
FR2751334B1 (fr) * 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
KR100533565B1 (ko) 2005-12-06
HUP0102042A3 (en) 2003-07-28
AU1974699A (en) 1999-08-02
AU744137B2 (en) 2002-02-14
KR20010034205A (ko) 2001-04-25
PL191098B1 (pl) 2006-03-31
EE200000421A1 (et) 2003-06-16
EP1049706B1 (fr) 2003-05-28
BR9907100A (pt) 2000-10-24
ZA99357B (en) 2000-07-19
DK1049706T3 (da) 2003-09-29
UY25357A1 (es) 2000-12-29
DE69908298D1 (de) 2003-07-03
PT1049706E (pt) 2003-09-30
HUP0102042A1 (hu) 2001-10-28
PL341874A1 (en) 2001-05-07
RU2193040C2 (ru) 2002-11-20
DE69908298T2 (de) 2004-04-01
CN1293679A (zh) 2001-05-02
HRP20000479A2 (en) 2001-02-28
NO316894B1 (no) 2004-06-14
SI1049706T1 (en) 2003-12-31
EP1049706A1 (fr) 2000-11-08
FR2773801A1 (fr) 1999-07-23
NZ505614A (en) 2003-02-28
MY125636A (en) 2006-08-30
TW550267B (en) 2003-09-01
HRP20000479A8 (hr) 2025-09-12
GT199900006A (es) 2000-07-12
BR9907100B1 (pt) 2013-09-03
IL137240A0 (en) 2001-07-24
HRP20000479B1 (hr) 2006-04-30
CZ20002636A3 (cs) 2000-11-15
HU228335B1 (en) 2013-03-28
NO20003661D0 (no) 2000-07-17
EE200000421A (et) 2001-12-17
UA61124C2 (en) 2003-11-17
SK284176B6 (sk) 2004-10-05
CZ299817B6 (cs) 2008-12-03
CN1172948C (zh) 2004-10-27
CA2318326C (en) 2010-07-06
HRP20000479B8 (hr) 2025-09-12
US6670338B1 (en) 2003-12-30
FR2773801B1 (fr) 2000-05-12
JP2002509154A (ja) 2002-03-26
IL137240A (en) 2007-10-31
DZ2706A1 (fr) 2003-09-01
NO20003661L (no) 2000-09-19
SK10792000A3 (sk) 2001-01-18
HK1029999A1 (zh) 2001-04-20
AR012779A1 (es) 2000-11-08
CO4970823A1 (es) 2000-11-07
EG23760A (en) 2007-08-08
ES2200494T3 (es) 2004-03-01
EE04194B1 (et) 2003-12-15
ATE241637T1 (de) 2003-06-15
CA2318326A1 (en) 1999-07-22
SA99191114B1 (ar) 2006-10-11
JP4695756B2 (ja) 2011-06-08
WO1999036428A1 (fr) 1999-07-22

Similar Documents

Publication Publication Date Title
TR200002077T2 (tr) Yeni pentasakaritler ve bunların hazırlanışı için prosesler ile bunları içinde bulunduran farmasötik kompozisyonlar.
TR200102800T2 (tr) Yeni bileşikler.
TW334418B (en) Stilbene derivatives and pharmaceutical compositions
BR0001468A (pt) ácidos dioxiciclopentil hidroxânicos
TR199901578T2 (xx) Klaritromisin form 0 kristali
TR200101398T2 (tr) Pirolidin türevleri-CCR-3 reseptörü antagonistleri.
BR9912073A (pt) Composições farmacêuticas que compreendem 2-quinolonas
AP9801378A0 (en) 9-amino-3- keto erythromycin derivatives.
TR200001140T2 (tr) 6, 11-Köprülü eritromisin türevleri.
BR0212353A (pt) Composto, composição farmacêutica, e, uso de um composto
NZ333281A (en) Asymmetric stilbene compounds for use as sun protection agents
BR9915692A (pt) Monohidrato de bromidrato de eletriptano
AU5192093A (en) Use of 4-hydroxy- or 4-aminobenzimidazole or their derivatives as couplers in oxidation dyeing compositions, and compositions and processes for implementation
ZA93494B (en) Napthalene amides and sulphonamides, processes for their preparation and pharmaceutical compositions containing them
TR199800714T2 (xx) Yeni $(3-Alkoksi-fenoksi)-etil]-dialkilamin t�revleri.
TR200101083T2 (tr) (7alfa,17alfa)-17-hidroksi- 7-metil-19-nor-17-pregn-5 (10)-en-20-in-3-on içeren yüksek saflıkta bileşim.
IL108856A0 (en) Hydroxymethyl-furazancarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
DE69102477D1 (de) 3-Aminochroman-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen.
AR014325A1 (es) Uso de glicinas n,n'-disustituidos o derivados de los mismos como desinfectantes antituberculosos y los desinfectantes antituberculososformulados con dichas glicinas n,n'-disustituidos
SE9904128D0 (sv) Novel compounds
TR199800210T2 (xx) Didepsipeptid temelli endoparazitisid kompozisyonlar, yeni didepsipeptidler ve bunlar�n �retimi i�in i�lemler.
NZ510116A (en) Tricyclic delta-3-piperidines as pharmaceuticals
BR9907426A (pt) Tetrahidronaftalenos
BR0000901A (pt) Derivados 4-fenil-4-heteroarilpiperidina
ATE14437T1 (de) Aminoglycosid-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zusammensetzungen und solche derivate zur verwendung als arzneimittel.