GT199900006A - Nuevos pentasacaridos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Nuevos pentasacaridos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
GT199900006A
GT199900006A GT199900006A GT199900006A GT199900006A GT 199900006 A GT199900006 A GT 199900006A GT 199900006 A GT199900006 A GT 199900006A GT 199900006 A GT199900006 A GT 199900006A GT 199900006 A GT199900006 A GT 199900006A
Authority
GT
Guatemala
Prior art keywords
pentacarides
procedure
contain
preparation
new
Prior art date
Application number
GT199900006A
Other languages
English (en)
Inventor
Maurice Petitou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT199900006A publication Critical patent/GT199900006A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Abstract

PENTASACARIDO BAJO FORMA ACIDA Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, CARACTERIZADO PORQUE SU FORMA ANIONICA TIENE LA FORMULA I, EN DONDE: R1 REPRESENTA ALQUILO (C1C3) ; R REPRESENTA HIDROGENO, UN GRUPO SO3, ALQUILO ( C1C3) O ACILO (C2C3); T REPRESENTA HIDROGENO O UN GRUPO ETILO; N REPRESENTA 1 O 2.
GT199900006A 1998-01-19 1999-01-19 Nuevos pentasacaridos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. GT199900006A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9800514A FR2773801B1 (fr) 1998-01-19 1998-01-19 Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
GT199900006A true GT199900006A (es) 2000-07-12

Family

ID=9521913

Family Applications (1)

Application Number Title Priority Date Filing Date
GT199900006A GT199900006A (es) 1998-01-19 1999-01-19 Nuevos pentasacaridos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Country Status (39)

Country Link
US (1) US6670338B1 (es)
EP (1) EP1049706B1 (es)
JP (1) JP4695756B2 (es)
KR (1) KR100533565B1 (es)
CN (1) CN1172948C (es)
AR (1) AR012779A1 (es)
AT (1) ATE241637T1 (es)
AU (1) AU744137B2 (es)
BR (1) BR9907100B1 (es)
CA (1) CA2318326C (es)
CO (1) CO4970823A1 (es)
CZ (1) CZ299817B6 (es)
DE (1) DE69908298T2 (es)
DK (1) DK1049706T3 (es)
DZ (1) DZ2706A1 (es)
EE (1) EE04194B1 (es)
EG (1) EG23760A (es)
ES (1) ES2200494T3 (es)
FR (1) FR2773801B1 (es)
GT (1) GT199900006A (es)
HK (1) HK1029999A1 (es)
HR (1) HRP20000479B1 (es)
HU (1) HU228335B1 (es)
IL (2) IL137240A0 (es)
MY (1) MY125636A (es)
NO (1) NO316894B1 (es)
NZ (1) NZ505614A (es)
PL (1) PL191098B1 (es)
PT (1) PT1049706E (es)
RU (1) RU2193040C2 (es)
SA (1) SA99191114B1 (es)
SI (1) SI1049706T1 (es)
SK (1) SK284176B6 (es)
TR (1) TR200002077T2 (es)
TW (1) TW550267B (es)
UA (1) UA61124C2 (es)
UY (1) UY25357A1 (es)
WO (1) WO1999036428A1 (es)
ZA (1) ZA99357B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
WO2004050637A2 (en) 2002-12-03 2004-06-17 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
CN100338084C (zh) * 2004-07-02 2007-09-19 北京大学 抑制异种器官移植免疫排斥反应的五糖抗原的合成方法
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
US20070191306A1 (en) * 2005-08-17 2007-08-16 Bristol-Myers Squibb Company FACTOR Xa INHIBITOR FORMULATION AND METHOD
EP1908768A1 (en) * 2006-10-05 2008-04-09 Endotis Pharma Anticoagulant compounds
KR101529061B1 (ko) 2008-05-30 2015-06-16 모멘타 파머슈티컬스 인코포레이티드 당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법
EP2323605A4 (en) * 2008-09-10 2014-02-05 Syneron Medical Ltd TRANSDERMAL RELEASE OF OLIGOSACCHARIDES
EP2464668B1 (en) * 2009-07-31 2022-12-07 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
US9556215B2 (en) 2011-06-17 2017-01-31 Carbomimetics Synthetic pentasaccharides having short half-life and high activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
DK0649854T3 (da) * 1993-09-01 2000-07-03 Akzo Nobel Nv Biskonjugater omfattende to saccharider og en spacer
FR2751334B1 (fr) * 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
CA2318326C (en) 2010-07-06
SI1049706T1 (en) 2003-12-31
DK1049706T3 (da) 2003-09-29
UA61124C2 (en) 2003-11-17
CZ299817B6 (cs) 2008-12-03
EE200000421A1 (et) 2003-06-16
JP4695756B2 (ja) 2011-06-08
CO4970823A1 (es) 2000-11-07
DE69908298T2 (de) 2004-04-01
WO1999036428A1 (fr) 1999-07-22
IL137240A (en) 2007-10-31
NZ505614A (en) 2003-02-28
IL137240A0 (en) 2001-07-24
CN1293679A (zh) 2001-05-02
MY125636A (en) 2006-08-30
BR9907100A (pt) 2000-10-24
CN1172948C (zh) 2004-10-27
AU1974699A (en) 1999-08-02
PL341874A1 (en) 2001-05-07
ES2200494T3 (es) 2004-03-01
RU2193040C2 (ru) 2002-11-20
CZ20002636A3 (cs) 2000-11-15
NO20003661D0 (no) 2000-07-17
NO20003661L (no) 2000-09-19
KR100533565B1 (ko) 2005-12-06
ATE241637T1 (de) 2003-06-15
AU744137B2 (en) 2002-02-14
UY25357A1 (es) 2000-12-29
US6670338B1 (en) 2003-12-30
TR200002077T2 (tr) 2000-12-21
CA2318326A1 (en) 1999-07-22
NO316894B1 (no) 2004-06-14
BR9907100B1 (pt) 2013-09-03
SK10792000A3 (sk) 2001-01-18
EP1049706B1 (fr) 2003-05-28
HUP0102042A1 (hu) 2001-10-28
HUP0102042A3 (en) 2003-07-28
KR20010034205A (ko) 2001-04-25
ZA99357B (en) 2000-07-19
SA99191114B1 (ar) 2006-10-11
HK1029999A1 (en) 2001-04-20
PT1049706E (pt) 2003-09-30
DZ2706A1 (fr) 2003-09-01
EP1049706A1 (fr) 2000-11-08
HRP20000479B1 (en) 2006-04-30
FR2773801B1 (fr) 2000-05-12
DE69908298D1 (de) 2003-07-03
TW550267B (en) 2003-09-01
SK284176B6 (sk) 2004-10-05
JP2002509154A (ja) 2002-03-26
EE04194B1 (et) 2003-12-15
HRP20000479A2 (en) 2001-02-28
EE200000421A (et) 2001-12-17
PL191098B1 (pl) 2006-03-31
HU228335B1 (en) 2013-03-28
EG23760A (en) 2007-08-08
FR2773801A1 (fr) 1999-07-23
AR012779A1 (es) 2000-11-08

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