GR3034135T3 - Lyophilized composition containing s(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione). - Google Patents

Lyophilized composition containing s(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione).

Info

Publication number
GR3034135T3
GR3034135T3 GR20000401830T GR20000401830T GR3034135T3 GR 3034135 T3 GR3034135 T3 GR 3034135T3 GR 20000401830 T GR20000401830 T GR 20000401830T GR 20000401830 T GR20000401830 T GR 20000401830T GR 3034135 T3 GR3034135 T3 GR 3034135T3
Authority
GR
Greece
Prior art keywords
icrf
piperazinedione
ethanediyl
bis
methyl
Prior art date
Application number
GR20000401830T
Other languages
English (en)
Inventor
Josephus Johannes Mar Holthuis
Alwinus Antonius Voetman
Original Assignee
Holthuis Josephus J M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10703550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3034135(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Holthuis Josephus J M filed Critical Holthuis Josephus J M
Publication of GR3034135T3 publication Critical patent/GR3034135T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
GR20000401830T 1991-10-25 2000-08-07 Lyophilized composition containing s(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione). GR3034135T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919122720A GB9122720D0 (en) 1991-10-25 1991-10-25 (s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)formulations and their preparation
PCT/EP1992/002400 WO1993007873A1 (en) 1991-10-25 1992-10-22 Lyophilized composition containing s(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)

Publications (1)

Publication Number Publication Date
GR3034135T3 true GR3034135T3 (en) 2000-11-30

Family

ID=10703550

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000401830T GR3034135T3 (en) 1991-10-25 2000-08-07 Lyophilized composition containing s(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione).

Country Status (11)

Country Link
EP (1) EP0619735B1 (el)
AT (1) ATE193205T1 (el)
AU (1) AU2791292A (el)
DE (1) DE69231098T2 (el)
DK (1) DK0619735T3 (el)
ES (1) ES2145748T3 (el)
GB (1) GB9122720D0 (el)
GR (1) GR3034135T3 (el)
MX (1) MX9206139A (el)
PT (1) PT101007B (el)
WO (1) WO1993007873A1 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265385B1 (en) * 1996-01-11 2001-07-24 Topo Target Aps Topoisomerase II poison and bis-dioxopiperazine derivative combination therapy
RU2252761C2 (ru) * 1999-03-12 2005-05-27 Топотаргет А/С Лечение случайной транссудации антрациклинов
WO2007062076A2 (en) * 2005-11-23 2007-05-31 Novartis Ag Dexrazoxane formulations and methods
CN114306251B (zh) * 2021-12-22 2023-08-11 乐普药业股份有限公司 一种含有右雷佐生的冻干制剂及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234935A (en) * 1967-07-03 1971-06-09 Nat Res Dev Piperazine derivatives
US4963551A (en) * 1987-12-21 1990-10-16 Erbamont Inc. Stable lyophilized form of (S)-(+)-bis-4,4'-(1-methyl-1,2-ethanediyl)2,6-piperazinedione and solutions thereof

Also Published As

Publication number Publication date
MX9206139A (es) 1993-07-01
DE69231098D1 (de) 2000-06-29
AU2791292A (en) 1993-05-21
PT101007A (pt) 1994-01-31
DK0619735T3 (da) 2000-12-04
WO1993007873A1 (en) 1993-04-29
GB9122720D0 (en) 1991-12-11
PT101007B (pt) 1999-07-30
EP0619735B1 (en) 2000-05-24
ES2145748T3 (es) 2000-07-16
ATE193205T1 (de) 2000-06-15
EP0619735A1 (en) 1994-10-19
DE69231098T2 (de) 2000-09-14

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