GB1446284A - Neurotoxin - Google Patents

Neurotoxin

Info

Publication number
GB1446284A
GB1446284A GB479674A GB479674A GB1446284A GB 1446284 A GB1446284 A GB 1446284A GB 479674 A GB479674 A GB 479674A GB 479674 A GB479674 A GB 479674A GB 1446284 A GB1446284 A GB 1446284A
Authority
GB
United Kingdom
Prior art keywords
modified
species
venom neurotoxin
composition
neurotoxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB479674A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1446284A publication Critical patent/GB1446284A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

1446284 Modified snake venom neurotoxin M J SANDERS 1 Feb 1974 [1 Feb 1973] 4796/74 Heading A5B Compositions for use in treating animals suffering from a degenerative neurological disease, comprise, in an administrable form, a detoxified and neurotropically active modified snake venom neurotoxin composition, at least a part of the modified venom neurotoxin being derived from a species of the Bungarus genus, the composition being atoxic and exhibiting at least a 30% inhibition of plaques in the Semliki Forest virus test. Part of the modified venom neurotoxin may be derived from a species of the Naja genus and/or from the species Crotalus terrificus terrificus. The composition may be prepared by oxygenating, at a pH of above 7 and a temperature of 15‹ to 40‹C, the respective snake venom neurotoxin(s), until atoxic, and dialyzing the resulting product. The compositions may be administered orally or parenterally in the form of tablets, powders, elixirs, solutions and physiological saline solutions.
GB479674A 1973-02-01 1974-02-01 Neurotoxin Expired GB1446284A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US328724A US3888977A (en) 1973-02-01 1973-02-01 Modified neurotoxin

Publications (1)

Publication Number Publication Date
GB1446284A true GB1446284A (en) 1976-08-18

Family

ID=23282151

Family Applications (1)

Application Number Title Priority Date Filing Date
GB479674A Expired GB1446284A (en) 1973-02-01 1974-02-01 Neurotoxin

Country Status (5)

Country Link
US (1) US3888977A (en)
CA (1) CA1028620A (en)
CH (1) CH612847A5 (en)
DE (1) DE2404416A1 (en)
GB (1) GB1446284A (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162303A (en) * 1977-06-17 1979-07-24 Sanders Murray J Potency and atoxicity test for modified neurotoxin
US4126676A (en) * 1977-07-22 1978-11-21 Sanders Murray J Modified neurotoxin derived from naja genus snake venom
US4292308A (en) * 1979-08-21 1981-09-29 Biotherapeutics, Inc. Treatment of animals exposed to or subject to exposure to organophosphate animal poisonous nerve agents
US4672107A (en) * 1985-04-15 1987-06-09 Inbex, Inc. Cell growth inhibitor and method
US5565431A (en) * 1994-06-20 1996-10-15 Lipps; Binie V. Cancer cell inhibitors and method
CA2253937A1 (en) * 1996-05-10 1997-11-20 Phylomed Corporation Methods for oxidizing disulfide bonds using ozone
BG65618B1 (en) * 2003-01-22 2009-03-31 Борис Алексиев Use of anti-snake venom serum for cerebral insult treatment
US20050031608A1 (en) * 2003-08-06 2005-02-10 Paul Reid Modified alpha-neurotoxins as painkillers
US20050255097A1 (en) * 2004-01-26 2005-11-17 Paul Reid Modified venom and venom components as anti-retroviral agents
US20060045875A1 (en) * 2004-09-02 2006-03-02 Reid Paul F Method of use of crotoxin as an anti-retroviral agent
US8034777B2 (en) * 2004-09-23 2011-10-11 Receptopharm, Inc. Modified anticholinergic neurotoxins as modulators of the autoimmune reaction
US20060088858A1 (en) * 2004-10-25 2006-04-27 Reid Paul F Modified venom and venom components as anti-retroviral agents
US20060088843A1 (en) * 2004-10-25 2006-04-27 Reid Paul F Modified venom and venom components as anti-retroviral agents
DE102004055891B4 (en) 2004-11-19 2007-08-30 Wiesner, Henning, Prof., Dr. Mixtures of snake venoms for disease control
US7902152B2 (en) * 2005-12-20 2011-03-08 Receptopharm, Inc. Use of cobratoxin as an analgesic
AR061669A1 (en) 2006-06-29 2008-09-10 Merz Pharma Gmbh & Co Kgaa HIGH FREQUENCY THERAPY APPLICATION WITH BOTULIN TOXIN
US10792344B2 (en) 2006-06-29 2020-10-06 Merz Pharma Gmbh & Co. Kgaa High frequency application of botulinum toxin therapy
US20080081048A1 (en) * 2006-10-02 2008-04-03 Laurence Raymond Production of modified neurotoxins
US7259237B1 (en) 2006-12-29 2007-08-21 Miller Kent D Pan-antiviral peptides
US9220743B2 (en) * 2010-01-22 2015-12-29 Nuovo Biologics, Llc Pan-antiviral peptides for protein kinase inhibition

Also Published As

Publication number Publication date
DE2404416A1 (en) 1974-08-08
CH612847A5 (en) 1979-08-31
US3888977A (en) 1975-06-10
CA1028620A (en) 1978-03-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee