ATE193205T1 - Lyophilisierte zusammensetzung, die s(+)-4,4'-(1- methyl-1,2-ethandiyl)-bis(2,6- piperazindion)enthält - Google Patents

Lyophilisierte zusammensetzung, die s(+)-4,4'-(1- methyl-1,2-ethandiyl)-bis(2,6- piperazindion)enthält

Info

Publication number
ATE193205T1
ATE193205T1 AT92921457T AT92921457T ATE193205T1 AT E193205 T1 ATE193205 T1 AT E193205T1 AT 92921457 T AT92921457 T AT 92921457T AT 92921457 T AT92921457 T AT 92921457T AT E193205 T1 ATE193205 T1 AT E193205T1
Authority
AT
Austria
Prior art keywords
icrf
piperazindione
ethanediyl
bis
methyl
Prior art date
Application number
AT92921457T
Other languages
English (en)
Inventor
Josephus Johannes Mar Holthuis
Alwinus Antonius Voetman
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10703550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE193205(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of ATE193205T1 publication Critical patent/ATE193205T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT92921457T 1991-10-25 1992-10-22 Lyophilisierte zusammensetzung, die s(+)-4,4'-(1- methyl-1,2-ethandiyl)-bis(2,6- piperazindion)enthält ATE193205T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919122720A GB9122720D0 (en) 1991-10-25 1991-10-25 (s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)formulations and their preparation
PCT/EP1992/002400 WO1993007873A1 (en) 1991-10-25 1992-10-22 Lyophilized composition containing s(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)

Publications (1)

Publication Number Publication Date
ATE193205T1 true ATE193205T1 (de) 2000-06-15

Family

ID=10703550

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92921457T ATE193205T1 (de) 1991-10-25 1992-10-22 Lyophilisierte zusammensetzung, die s(+)-4,4'-(1- methyl-1,2-ethandiyl)-bis(2,6- piperazindion)enthält

Country Status (11)

Country Link
EP (1) EP0619735B1 (de)
AT (1) ATE193205T1 (de)
AU (1) AU2791292A (de)
DE (1) DE69231098T2 (de)
DK (1) DK0619735T3 (de)
ES (1) ES2145748T3 (de)
GB (1) GB9122720D0 (de)
GR (1) GR3034135T3 (de)
MX (1) MX9206139A (de)
PT (1) PT101007B (de)
WO (1) WO1993007873A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265385B1 (en) * 1996-01-11 2001-07-24 Topo Target Aps Topoisomerase II poison and bis-dioxopiperazine derivative combination therapy
DE60010241T2 (de) 1999-03-12 2005-01-13 Topotarget A/S Dexrazoxan zur behandlung von unerwünschter extravasation von anthrazyklinen
WO2007062076A2 (en) * 2005-11-23 2007-05-31 Novartis Ag Dexrazoxane formulations and methods
CN114306251B (zh) * 2021-12-22 2023-08-11 乐普药业股份有限公司 一种含有右雷佐生的冻干制剂及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234935A (en) * 1967-07-03 1971-06-09 Nat Res Dev Piperazine derivatives
US4963551A (en) * 1987-12-21 1990-10-16 Erbamont Inc. Stable lyophilized form of (S)-(+)-bis-4,4'-(1-methyl-1,2-ethanediyl)2,6-piperazinedione and solutions thereof

Also Published As

Publication number Publication date
AU2791292A (en) 1993-05-21
GR3034135T3 (en) 2000-11-30
MX9206139A (es) 1993-07-01
DK0619735T3 (da) 2000-12-04
DE69231098D1 (de) 2000-06-29
WO1993007873A1 (en) 1993-04-29
PT101007A (pt) 1994-01-31
DE69231098T2 (de) 2000-09-14
EP0619735B1 (de) 2000-05-24
EP0619735A1 (de) 1994-10-19
ES2145748T3 (es) 2000-07-16
PT101007B (pt) 1999-07-30
GB9122720D0 (en) 1991-12-11

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Legal Events

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UEP Publication of translation of european patent specification