PT101007A - Preparado liofilizado e estavel de icrf-187 e seu uso e processo de preparacao de liofilizado de icrf-187 - Google Patents

Preparado liofilizado e estavel de icrf-187 e seu uso e processo de preparacao de liofilizado de icrf-187

Info

Publication number
PT101007A
PT101007A PT101007A PT10100792A PT101007A PT 101007 A PT101007 A PT 101007A PT 101007 A PT101007 A PT 101007A PT 10100792 A PT10100792 A PT 10100792A PT 101007 A PT101007 A PT 101007A
Authority
PT
Portugal
Prior art keywords
icrf
lyophilized
preparation process
stably prepared
hours
Prior art date
Application number
PT101007A
Other languages
English (en)
Other versions
PT101007B (pt
Original Assignee
Josephus Johannes Maria Holtui
Voetman Alwinus Antonius
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10703550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT101007(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Josephus Johannes Maria Holtui, Voetman Alwinus Antonius filed Critical Josephus Johannes Maria Holtui
Publication of PT101007A publication Critical patent/PT101007A/pt
Publication of PT101007B publication Critical patent/PT101007B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PT101007A 1991-10-25 1992-10-23 Preparado liofilizado e estavel de icrf-187 e seu uso e processo de preparacao de liofilizado de icrf-187 PT101007B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919122720A GB9122720D0 (en) 1991-10-25 1991-10-25 (s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)formulations and their preparation

Publications (2)

Publication Number Publication Date
PT101007A true PT101007A (pt) 1994-01-31
PT101007B PT101007B (pt) 1999-07-30

Family

ID=10703550

Family Applications (1)

Application Number Title Priority Date Filing Date
PT101007A PT101007B (pt) 1991-10-25 1992-10-23 Preparado liofilizado e estavel de icrf-187 e seu uso e processo de preparacao de liofilizado de icrf-187

Country Status (11)

Country Link
EP (1) EP0619735B1 (pt)
AT (1) ATE193205T1 (pt)
AU (1) AU2791292A (pt)
DE (1) DE69231098T2 (pt)
DK (1) DK0619735T3 (pt)
ES (1) ES2145748T3 (pt)
GB (1) GB9122720D0 (pt)
GR (1) GR3034135T3 (pt)
MX (1) MX9206139A (pt)
PT (1) PT101007B (pt)
WO (1) WO1993007873A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265385B1 (en) * 1996-01-11 2001-07-24 Topo Target Aps Topoisomerase II poison and bis-dioxopiperazine derivative combination therapy
DK1162981T3 (da) * 1999-03-12 2004-08-16 Topotarget As Dexrazoran til behandling af utilsigtet ekstravasation af anthracycliner
WO2007062076A2 (en) * 2005-11-23 2007-05-31 Novartis Ag Dexrazoxane formulations and methods
CN114306251B (zh) * 2021-12-22 2023-08-11 乐普药业股份有限公司 一种含有右雷佐生的冻干制剂及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234935A (en) * 1967-07-03 1971-06-09 Nat Res Dev Piperazine derivatives
US4963551A (en) * 1987-12-21 1990-10-16 Erbamont Inc. Stable lyophilized form of (S)-(+)-bis-4,4'-(1-methyl-1,2-ethanediyl)2,6-piperazinedione and solutions thereof

Also Published As

Publication number Publication date
ES2145748T3 (es) 2000-07-16
EP0619735B1 (en) 2000-05-24
DE69231098T2 (de) 2000-09-14
DK0619735T3 (da) 2000-12-04
DE69231098D1 (de) 2000-06-29
EP0619735A1 (en) 1994-10-19
PT101007B (pt) 1999-07-30
ATE193205T1 (de) 2000-06-15
MX9206139A (es) 1993-07-01
WO1993007873A1 (en) 1993-04-29
GR3034135T3 (en) 2000-11-30
GB9122720D0 (en) 1991-12-11
AU2791292A (en) 1993-05-21

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Legal Events

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BB1A Laying open of patent application

Effective date: 19930708

FG3A Patent granted, date of granting

Effective date: 19990420

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

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Effective date: 20140421