ATE190628T1 - Zusammensetzungen von wachstumsfaktoren, herstellung und verwendung - Google Patents
Zusammensetzungen von wachstumsfaktoren, herstellung und verwendungInfo
- Publication number
- ATE190628T1 ATE190628T1 AT91917666T AT91917666T ATE190628T1 AT E190628 T1 ATE190628 T1 AT E190628T1 AT 91917666 T AT91917666 T AT 91917666T AT 91917666 T AT91917666 T AT 91917666T AT E190628 T1 ATE190628 T1 AT E190628T1
- Authority
- AT
- Austria
- Prior art keywords
- pure
- species
- hegf1
- nicked
- growth factor
- Prior art date
Links
- 239000003102 growth factor Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 102000009024 Epidermal Growth Factor Human genes 0.000 abstract 1
- 101800003838 Epidermal growth factor Proteins 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 239000000039 congener Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 230000002183 duodenal effect Effects 0.000 abstract 1
- 230000007515 enzymatic degradation Effects 0.000 abstract 1
- 229940116977 epidermal growth factor Drugs 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56152590A | 1990-08-02 | 1990-08-02 | |
| US59133990A | 1990-10-01 | 1990-10-01 | |
| PCT/US1991/005396 WO1992002246A1 (en) | 1990-08-02 | 1991-07-30 | Growth factor compositions, preparation and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE190628T1 true ATE190628T1 (de) | 2000-04-15 |
Family
ID=27072670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91917666T ATE190628T1 (de) | 1990-08-02 | 1991-07-30 | Zusammensetzungen von wachstumsfaktoren, herstellung und verwendung |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0541726B1 (de) |
| JP (1) | JP3195793B2 (de) |
| AT (1) | ATE190628T1 (de) |
| AU (1) | AU660421B2 (de) |
| DE (1) | DE69132050T2 (de) |
| DK (1) | DK0541726T3 (de) |
| ES (1) | ES2145740T3 (de) |
| GR (1) | GR3033649T3 (de) |
| IE (1) | IE912738A1 (de) |
| PT (1) | PT98538B (de) |
| WO (1) | WO1992002246A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5434135A (en) * | 1990-08-02 | 1995-07-18 | Indu Parikh | Growth factor compositions, preparation and use |
| US6558952B1 (en) * | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
| US5814308A (en) * | 1996-03-26 | 1998-09-29 | Zhang; Ke | Methods for the treatment of gastrointestinal tract disorders |
| US6579308B1 (en) | 2000-11-28 | 2003-06-17 | Scimed Life Systems, Inc. | Stent devices with detachable distal or proximal wires |
| WO2024168796A1 (zh) * | 2023-02-17 | 2024-08-22 | 固德生技有限公司 | 表皮生长因子在制备用于治疗胃溃疡的药物上的应用 |
| CN116036241A (zh) * | 2023-02-17 | 2023-05-02 | 固德生技有限公司 | 表皮生长因子在制备用于治疗胃溃疡的药物上的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3813834A (en) * | 1970-05-28 | 1974-06-04 | Prod Eng Inc | Joist with nailing strip and positioning members |
| IE38892B1 (en) * | 1973-03-28 | 1978-06-21 | Ici Ltd | Pharmaceutical compositions |
| GB1461105A (en) * | 1974-09-11 | 1977-01-13 | Ici Ltd | Gastric acid-inhibiting polypeptide |
| IE53166B1 (en) * | 1980-08-05 | 1988-08-03 | Searle & Co | Synthetic urogastrone gene,corresponding plasmid recombinants,transformed cells,production thereof and urogastrone expression |
| GB8409960D0 (en) * | 1984-04-17 | 1984-05-31 | Searle & Co | Therapeutic method |
| GB8509448D0 (en) * | 1985-04-12 | 1985-05-15 | Ici Plc | Urogastrone |
| EP0436625A4 (en) * | 1988-09-26 | 1991-08-21 | The Salk Institute Biotechnology Industrial Associates, Inc. | Mixed feed recombinant yeast fermentation |
-
1991
- 1991-07-30 ES ES91917666T patent/ES2145740T3/es not_active Expired - Lifetime
- 1991-07-30 AT AT91917666T patent/ATE190628T1/de not_active IP Right Cessation
- 1991-07-30 DE DE69132050T patent/DE69132050T2/de not_active Expired - Fee Related
- 1991-07-30 JP JP51602791A patent/JP3195793B2/ja not_active Expired - Fee Related
- 1991-07-30 DK DK91917666T patent/DK0541726T3/da active
- 1991-07-30 AU AU86445/91A patent/AU660421B2/en not_active Ceased
- 1991-07-30 WO PCT/US1991/005396 patent/WO1992002246A1/en not_active Ceased
- 1991-07-30 EP EP91917666A patent/EP0541726B1/de not_active Expired - Lifetime
- 1991-08-01 IE IE273891A patent/IE912738A1/en not_active IP Right Cessation
- 1991-08-01 PT PT98538A patent/PT98538B/pt not_active IP Right Cessation
-
2000
- 2000-06-13 GR GR20000401336T patent/GR3033649T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK0541726T3 (da) | 2000-08-21 |
| GR3033649T3 (en) | 2000-10-31 |
| PT98538B (pt) | 1999-01-29 |
| DE69132050T2 (de) | 2001-01-11 |
| DE69132050D1 (de) | 2000-04-20 |
| EP0541726A1 (de) | 1993-05-19 |
| AU8644591A (en) | 1992-03-02 |
| AU660421B2 (en) | 1995-06-29 |
| EP0541726A4 (en) | 1993-12-29 |
| EP0541726B1 (de) | 2000-03-15 |
| IE912738A1 (en) | 1992-02-12 |
| JP3195793B2 (ja) | 2001-08-06 |
| ES2145740T3 (es) | 2000-07-16 |
| WO1992002246A1 (en) | 1992-02-20 |
| JPH06502626A (ja) | 1994-03-24 |
| PT98538A (pt) | 1992-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |