GR3017632T3 - Thiazolidine compounds, their preparation and their therapeutic uses. - Google Patents

Thiazolidine compounds, their preparation and their therapeutic uses.

Info

Publication number
GR3017632T3
GR3017632T3 GR950402745T GR950402745T GR3017632T3 GR 3017632 T3 GR3017632 T3 GR 3017632T3 GR 950402745 T GR950402745 T GR 950402745T GR 950402745 T GR950402745 T GR 950402745T GR 3017632 T3 GR3017632 T3 GR 3017632T3
Authority
GR
Greece
Prior art keywords
alkyl
hydrogen
preparation
therapeutic uses
optionally substituted
Prior art date
Application number
GR950402745T
Other languages
Greek (el)
English (en)
Inventor
Takao Yoshioka
Takahide Nishi
Tsutomu Kanai
Yuichi Aizawa
Kunio Wada
Takashi Fujita
Hiroyoshi Horikoshi
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of GR3017632T3 publication Critical patent/GR3017632T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
GR950402745T 1991-12-26 1995-10-04 Thiazolidine compounds, their preparation and their therapeutic uses. GR3017632T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457191 1991-12-26

Publications (1)

Publication Number Publication Date
GR3017632T3 true GR3017632T3 (en) 1996-01-31

Family

ID=18370304

Family Applications (1)

Application Number Title Priority Date Filing Date
GR950402745T GR3017632T3 (en) 1991-12-26 1995-10-04 Thiazolidine compounds, their preparation and their therapeutic uses.

Country Status (21)

Country Link
EP (1) EP0549365B1 (show.php)
JP (1) JP2833949B2 (show.php)
CN (1) CN1032751C (show.php)
AT (1) ATE126221T1 (show.php)
AU (1) AU654223B2 (show.php)
CA (1) CA2086277A1 (show.php)
CZ (1) CZ389792A3 (show.php)
DE (1) DE69204041T2 (show.php)
DK (1) DK0549365T3 (show.php)
ES (1) ES2078671T3 (show.php)
FI (1) FI925849A7 (show.php)
GR (1) GR3017632T3 (show.php)
HK (1) HK196095A (show.php)
HU (1) HU215450B (show.php)
IL (1) IL104238A (show.php)
MX (1) MX9207595A (show.php)
NO (1) NO302471B1 (show.php)
NZ (1) NZ245612A (show.php)
RU (1) RU2095354C1 (show.php)
TW (1) TW211007B (show.php)
ZA (1) ZA9210021B (show.php)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
CA2146701A1 (en) * 1994-04-11 1995-10-12 Takashi Fujita Heterocyclic compounds having anti-diabetic activity, their preparation and their use
EP0783888A1 (en) 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
US6331633B1 (en) * 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
DE19828114A1 (de) * 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19828113A1 (de) * 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19926233C1 (de) * 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
ES2248242T3 (es) * 2000-04-21 2006-03-16 Pfizer Products Inc. Ligandos de receptores tiroideos.
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003531200A (ja) * 2000-04-24 2003-10-21 アリックス セラピューティクス 糖尿病、高脂血症、高コレステロール血症、およびアテローム性動脈硬化症の治療のための材料と方法
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法
CN101454006B (zh) 2006-03-16 2012-12-26 新陈代谢解决方案开发公司 用于治疗高血压以及用于降低血脂的噻唑烷二酮类似物
ES2654908T3 (es) 2006-03-16 2018-02-15 Metabolic Solutions Development Company Llc Análogos de tiazolidindiona para el tratamiento de enfermedades mediadas por una inflamación metabólica
PL2203433T3 (pl) * 2007-09-14 2013-04-30 Metabolic Solutions Dev Co Llc 5-(4-(2-(3-metoksyfenylo)-2-oksoetoksy)benzylo)tiazolidyno-2,4-dion do stosowania w leczeniu cukrzycy
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
US8912335B2 (en) 2009-12-15 2014-12-16 Metabolic Solutions Development Company, Llc PPAR-sparing thiazolidinedione salts for the treatment of metabolic diseases
EP2560956B1 (en) * 2010-04-19 2016-10-26 Octeta Therapeutics, LLC Novel synthesis for thiazolidinedione compounds
CN102946860A (zh) * 2010-04-21 2013-02-27 新陈代谢解决方案开发公司 噻唑烷二酮类似物
RU2593370C2 (ru) 2010-08-10 2016-08-10 Октета Терапьютикс, ЭлЭлСи Новый способ синтеза соединений тиазолидиндиона
CN115433144B (zh) * 2022-10-09 2023-09-19 燃点(南京)生物医药科技有限公司 一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

Also Published As

Publication number Publication date
ATE126221T1 (de) 1995-08-15
HUT67788A (en) 1995-04-28
FI925849A7 (fi) 1993-06-27
CN1074680A (zh) 1993-07-28
JPH05239041A (ja) 1993-09-17
NO924964L (no) 1993-06-28
RU2095354C1 (ru) 1997-11-10
EP0549365B1 (en) 1995-08-09
TW211007B (show.php) 1993-08-11
MX9207595A (es) 1994-06-30
NO302471B1 (no) 1998-03-09
NO924964D0 (no) 1992-12-22
AU3043192A (en) 1993-07-01
CN1032751C (zh) 1996-09-11
IL104238A (en) 1996-10-31
EP0549365A1 (en) 1993-06-30
DE69204041D1 (de) 1995-09-14
ZA9210021B (en) 1993-07-02
HK196095A (en) 1996-01-05
JP2833949B2 (ja) 1998-12-09
HU215450B (hu) 1999-04-28
ES2078671T3 (es) 1995-12-16
DE69204041T2 (de) 1996-03-28
FI925849A0 (fi) 1992-12-23
NZ245612A (en) 1994-06-27
AU654223B2 (en) 1994-10-27
DK0549365T3 (da) 1995-12-18
HU9204130D0 (en) 1993-04-28
CA2086277A1 (en) 1993-06-27
CZ389792A3 (en) 1994-01-19

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