GR3006925T3 - - Google Patents

Info

Publication number
GR3006925T3
GR3006925T3 GR930400172T GR930400172T GR3006925T3 GR 3006925 T3 GR3006925 T3 GR 3006925T3 GR 930400172 T GR930400172 T GR 930400172T GR 930400172 T GR930400172 T GR 930400172T GR 3006925 T3 GR3006925 T3 GR 3006925T3
Authority
GR
Greece
Application number
GR930400172T
Other languages
Greek (el)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GR3006925T3 publication Critical patent/GR3006925T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
GR930400172T 1989-01-23 1993-01-28 GR3006925T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1989/000275 WO1990008148A1 (en) 1989-01-23 1989-01-23 Bis-aza-bicyclic anxiolytic agents
PCT/US1989/003811 WO1990008144A1 (en) 1989-01-23 1989-09-01 Bis-aza-bicyclic anxiolytic agents

Publications (1)

Publication Number Publication Date
GR3006925T3 true GR3006925T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-30

Family

ID=22214801

Family Applications (1)

Application Number Title Priority Date Filing Date
GR930400172T GR3006925T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-01-23 1993-01-28

Country Status (38)

Country Link
US (1) US5122525A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0380217B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0643427B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR910009289B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1022186C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AP (1) AP128A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR246969A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE82574T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU614214B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BA (1) BA98302A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG51046A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2008108C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ277698B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD291560A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69000467T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0380217T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EG (1) EG19306A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2053094T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI95381C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3006925T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU215154B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE62670B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL93073A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IS (1) IS1667B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MA (1) MA21735A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX19222A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY104861A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO175978C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ232168A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (1) OA10041A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL163836B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT92919B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO110142B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2015977C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK279339B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (2) WO1990008148A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU47554B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA90430B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990008148A1 (en) * 1989-01-23 1990-07-26 Pfizer Inc. Bis-aza-bicyclic anxiolytic agents
WO1992000075A1 (en) * 1990-06-29 1992-01-09 Pfizer Inc. Pyridopyrazine derivatives for treating substance abuse and addiction
ATE120746T1 (de) * 1991-01-31 1995-04-15 Pfizer Recematspaltung von trans-2-(2-pyrimidinyl)-7- (hydroxymethyl)octahydro-2h-pyrido(1,2-a>- pyrazin.
US5157034A (en) * 1991-02-27 1992-10-20 Pfizer Inc. Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines
DK0573464T3 (da) * 1991-02-27 1997-09-01 Pfizer Fremgangsmåde til fremstilling af trans-piperidin-2,5-dicarboxylater
US5185449A (en) * 1991-02-27 1993-02-09 Pfizer Inc. Process and intermediate for certain bis-aza-bicyclic anxiolytic agents
US5311195A (en) * 1991-08-30 1994-05-10 Etak, Inc. Combined relative and absolute positioning method and apparatus
AU655071B2 (en) * 1991-09-25 1994-12-01 Pfizer Inc. Neuroleptic 2-substituted perhydro-1-H-pyrido(1,2a) pyrazines
JP2753146B2 (ja) * 1992-06-16 1998-05-18 ファイザー・インコーポレーテッド ビス−アザー二環式抗不安薬の製法および中間体
WO1994006794A1 (en) * 1992-09-24 1994-03-31 National Institutes Of Health Aralkyl diazabicycloalkane derivatives for cns disorders
IL104506A (en) * 1993-01-25 1997-11-20 Israel State Fast changing heating- cooling device and method, particularly for cryogenic and/or surgical use
US5637713A (en) * 1993-08-20 1997-06-10 Pfizer Inc. Process for preparing trans-piperidine-2,5-dicarboxylates
US5455350A (en) * 1993-10-13 1995-10-03 Pfizer Inc. Process and intermediate for certain bis-aza-bicyclic anxiolytic agents
IL107460A (en) * 1993-11-01 1999-06-20 Israel State Controlled cryogenic contact system
KR100244848B1 (ko) * 1994-09-30 2000-03-02 디. 제이. 우드, 스피겔 알렌 제이 2,7-치환된 옥타하이드로-1H-피리도[1,2-a] 피라진 유도체
US6231833B1 (en) 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
WO1996010570A1 (en) * 1994-09-30 1996-04-11 Pfizer Inc. NEUROLEPTIC 2,7-DISUBSTITUTED PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES
SI0874849T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1995-12-21 2001-12-31 Pfizer
CZ434998A3 (cs) * 1996-07-01 1999-11-17 Pfizer Inc. Způsob výroby (7S,trans)-2-(2-pyrimidinyl)-7-(hydroxymethyl)oktahydro-2H-pyrido[1,2-a]-pyrazinu
PA8469101A1 (es) * 1998-04-09 2000-09-29 Pfizer Prod Inc Ligandos azabiciclicos de receptores 5ht1
US6251893B1 (en) * 1998-06-15 2001-06-26 Nps Allelix Corp. Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity
HN1999000146A (es) * 1998-09-21 2000-11-11 Pfizer Prod Inc Agentes farmaceuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas.
US20020016334A1 (en) * 2000-07-31 2002-02-07 Coe Jotham Wadsworth Pharmaceutical composition for the treatment of attention deficit hyperactivity disorder (ADHD)
US6670476B2 (en) 2000-11-29 2003-12-30 Pfizer Inc. Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine
KR20070074667A (ko) * 2003-03-12 2007-07-12 화이자 프로덕츠 인크. 피리딜옥시메틸 및 벤즈이속사졸 아자비시클릭 유도체
WO2004092173A2 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. A2a adenosine receptor antagonists
US7671072B2 (en) * 2003-11-26 2010-03-02 Pfizer Inc. Aminopyrazole derivatives as GSK-3 inhibitors
WO2005115396A2 (en) * 2004-05-27 2005-12-08 Warner-Lambert Company Llc Combination of atomoxetine and a 5t1a receptor agonist for treating adhd and other disorders
US7658206B2 (en) 2006-12-05 2010-02-09 Kohler Co. Plumbing valve with stick control handle

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388128A (en) * 1965-09-03 1968-06-11 Allan R. Day Substituted 1, 4-diazabicyclo [4. 4. 9] decanes
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
US4339579A (en) * 1980-12-29 1982-07-13 American Home Products Corporation 2,6-Bis-(pyrrolopyrazinyl)pyrazines
US4400511A (en) * 1982-05-07 1983-08-23 American Home Products Corporation 2-Substituted octahydropyrrolo(1,2-A)-pyrazine-3-carboxylic acids
US4414389A (en) * 1982-05-25 1983-11-08 American Home Products Corporation 4-Substituted-piperidino carboxamides
US4517187A (en) * 1982-10-18 1985-05-14 Pennwalt Corporation 1,3,4,6,7-11b-Hexahydro-7-phenyl-2H-pyrazino[2,1-a]isoquinolines methods of preparation, and use as antidepressants
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE3409440A1 (de) * 1984-03-15 1985-09-26 Bayer Ag, 5090 Leverkusen Imidazo(1,5-a)pyridyl-methan- und imidazo(1,5-b)pyridazinylmethan-derivate, ihre herstellung und sie enthaltende aufzeichnungsmaterialien
IT1204803B (it) * 1986-02-17 1989-03-10 Acraf Composto farmacologicamente attivo e composizioni farmaceutiche che lo contengono,procedimento per prepararlo e intermedio utile in detto procedimento
US4788290A (en) * 1987-12-11 1988-11-29 American Home Products Corporation Serotonergic pyrazine derivatives
JP2668259B2 (ja) * 1988-02-18 1997-10-27 塩野義製薬株式会社 複素環化合物および抗潰瘍剤
WO1990008148A1 (en) * 1989-01-23 1990-07-26 Pfizer Inc. Bis-aza-bicyclic anxiolytic agents

Also Published As

Publication number Publication date
DD291560A5 (de) 1991-07-04
NO175978C (no) 1995-01-11
WO1990008148A1 (en) 1990-07-26
IE62670B1 (en) 1995-03-08
FI913510A0 (fi) 1991-07-22
BA98302A (bs) 2001-09-14
AU4867990A (en) 1990-07-26
IS3529A7 (is) 1990-07-24
DE69000467T2 (de) 1993-04-01
BG51046A3 (bg) 1993-01-15
AP128A (en) 1991-03-20
PT92919A (pt) 1990-07-31
NO912863L (no) 1991-07-22
RO110142B1 (ro) 1995-10-30
DK0380217T3 (da) 1992-12-14
OA10041A (en) 1996-10-14
FI95381C (fi) 1996-01-25
EG19306A (en) 1995-01-31
NZ232168A (en) 1991-08-27
AP9000158A0 (en) 1990-01-31
AU614214B2 (en) 1991-08-22
CN1044464A (zh) 1990-08-08
CA2008108A1 (en) 1990-07-23
MA21735A1 (fr) 1990-10-01
NO175978B (no) 1994-10-03
MX19222A (es) 1993-12-01
HU215154B (hu) 2000-09-28
ZA90430B (en) 1991-08-28
DE69000467D1 (de) 1992-12-24
CZ277698B6 (en) 1993-03-17
ATE82574T1 (de) 1992-12-15
EP0380217A1 (en) 1990-08-01
IS1667B (is) 1997-11-14
CS29990A3 (en) 1992-11-18
MY104861A (en) 1994-06-30
WO1990008144A1 (en) 1990-07-26
YU47554B (sh) 1995-10-03
YU11190A (sh) 1993-05-28
JPH0643427B2 (ja) 1994-06-08
AR246969A1 (es) 1994-10-31
CN1022186C (zh) 1993-09-22
FI95381B (fi) 1995-10-13
PL163836B1 (pl) 1994-05-31
CA2008108C (en) 1995-08-08
KR910009289B1 (ko) 1991-11-09
US5122525A (en) 1992-06-16
JPH02233681A (ja) 1990-09-17
KR900011774A (ko) 1990-08-02
EP0380217B1 (en) 1992-11-19
RU2015977C1 (ru) 1994-07-15
IE900225L (en) 1990-07-23
IL93073A (en) 1994-05-30
HUT63163A (en) 1993-07-28
SK279339B6 (sk) 1998-10-07
NO912863D0 (no) 1991-07-22
ES2053094T3 (es) 1994-07-16
PT92919B (pt) 1995-12-29

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