ATE120746T1 - Recematspaltung von trans-2-(2-pyrimidinyl)-7- (hydroxymethyl)octahydro-2h-pyrido(1,2-a>- pyrazin. - Google Patents

Recematspaltung von trans-2-(2-pyrimidinyl)-7- (hydroxymethyl)octahydro-2h-pyrido(1,2-a>- pyrazin.

Info

Publication number
ATE120746T1
ATE120746T1 AT92902650T AT92902650T ATE120746T1 AT E120746 T1 ATE120746 T1 AT E120746T1 AT 92902650 T AT92902650 T AT 92902650T AT 92902650 T AT92902650 T AT 92902650T AT E120746 T1 ATE120746 T1 AT E120746T1
Authority
AT
Austria
Prior art keywords
octahydro
pyrido
pyrimidinyl
hydroxymethyl
trans
Prior art date
Application number
AT92902650T
Other languages
English (en)
Inventor
Charles W Murtiashaw
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE120746T1 publication Critical patent/ATE120746T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT92902650T 1991-01-31 1991-12-05 Recematspaltung von trans-2-(2-pyrimidinyl)-7- (hydroxymethyl)octahydro-2h-pyrido(1,2-a>- pyrazin. ATE120746T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64868691A 1991-01-31 1991-01-31

Publications (1)

Publication Number Publication Date
ATE120746T1 true ATE120746T1 (de) 1995-04-15

Family

ID=24601808

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92902650T ATE120746T1 (de) 1991-01-31 1991-12-05 Recematspaltung von trans-2-(2-pyrimidinyl)-7- (hydroxymethyl)octahydro-2h-pyrido(1,2-a>- pyrazin.

Country Status (12)

Country Link
EP (1) EP0569387B1 (de)
JP (1) JP2609410B2 (de)
AT (1) ATE120746T1 (de)
CA (1) CA2099563C (de)
DE (1) DE69108743T2 (de)
DK (1) DK0569387T3 (de)
ES (1) ES2072141T3 (de)
FI (1) FI100400B (de)
GR (1) GR3015726T3 (de)
IE (1) IE67777B1 (de)
PT (1) PT100061B (de)
WO (1) WO1992013858A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2753146B2 (ja) * 1992-06-16 1998-05-18 ファイザー・インコーポレーテッド ビス−アザー二環式抗不安薬の製法および中間体
US5731307A (en) * 1994-09-30 1998-03-24 Pfizer, Inc. Neuroleptic 2,7-disubtituted perhydro-1h-pyrido 1, 2-A!pyrazines
JP3287574B2 (ja) * 1994-09-30 2002-06-04 ファイザー・インク ２，７−置換オクタヒドロ−１ｈ−ピリド［１，２−ａ］ピラジン誘導体
CN1221418A (zh) * 1996-07-01 1999-06-30 辉瑞大药厂 (7s,反)－2－(2－嘧啶基)－7－(羟甲基)八氢－2h－吡啶并[1,2－a)吡嗪的制备
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
US6670476B2 (en) 2000-11-29 2003-12-30 Pfizer Inc. Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine
DK1337533T3 (da) * 2000-11-29 2006-08-21 Pfizer Prod Inc Resolvering af trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido-1,2a)pyrazin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX19222A (es) * 1989-01-23 1993-12-01 Pfizer Agentes ansioliticos bis-aza-biciclicos

Also Published As

Publication number Publication date
IE67777B1 (en) 1996-04-17
EP0569387B1 (de) 1995-04-05
EP0569387A1 (de) 1993-11-18
PT100061A (pt) 1993-03-31
FI100400B (fi) 1997-11-28
FI933422A0 (fi) 1993-07-30
DE69108743T2 (de) 1995-08-17
JP2609410B2 (ja) 1997-05-14
GR3015726T3 (en) 1995-07-31
JPH06502181A (ja) 1994-03-10
CA2099563C (en) 1998-09-29
ES2072141T3 (es) 1995-07-01
CA2099563A1 (en) 1992-08-01
IE920303A1 (en) 1992-07-29
WO1992013858A1 (en) 1992-08-20
DK0569387T3 (da) 1995-07-03
PT100061B (pt) 1999-06-30
FI933422A (fi) 1993-07-30
DE69108743D1 (de) 1995-05-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee