GR1000609B - Μεθοδος παραγωγης πορφυρινων. - Google Patents
Μεθοδος παραγωγης πορφυρινων.Info
- Publication number
- GR1000609B GR1000609B GR890100817A GR890100817A GR1000609B GR 1000609 B GR1000609 B GR 1000609B GR 890100817 A GR890100817 A GR 890100817A GR 890100817 A GR890100817 A GR 890100817A GR 1000609 B GR1000609 B GR 1000609B
- Authority
- GR
- Greece
- Prior art keywords
- cells
- protoporphyrin
- profyrina
- production method
- disclosed
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 4
- KSFOVUSSGSKXFI-GAQDCDSVSA-N CC1=C/2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(C=C)=C5C)C(C=C)=C4C)C(C)=C3CCC(O)=O)=C1CCC(O)=O Chemical compound CC1=C/2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(C=C)=C5C)C(C=C)=C4C)C(C)=C3CCC(O)=O)=C1CCC(O)=O KSFOVUSSGSKXFI-GAQDCDSVSA-N 0.000 abstract 3
- 229950003776 protoporphyrin Drugs 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 108020001991 Protoporphyrinogen Oxidase Proteins 0.000 abstract 1
- 102000005135 Protoporphyrinogen oxidase Human genes 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- UHSGPDMIQQYNAX-UHFFFAOYSA-N protoporphyrinogen Chemical compound C1C(=C(C=2C=C)C)NC=2CC(=C(C=2CCC(O)=O)C)NC=2CC(N2)=C(CCC(O)=O)C(C)=C2CC2=C(C)C(C=C)=C1N2 UHSGPDMIQQYNAX-UHFFFAOYSA-N 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28515188A | 1988-12-12 | 1988-12-12 | |
| US33500789A | 1989-04-07 | 1989-04-07 | |
| US35133189A | 1989-05-03 | 1989-05-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GR890100817A GR890100817A (en) | 1991-03-15 |
| GR1000609B true GR1000609B (el) | 1992-08-31 |
Family
ID=27403508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR890100817A GR1000609B (el) | 1988-12-12 | 1989-12-12 | Μεθοδος παραγωγης πορφυρινων. |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0447491B1 (https=) |
| JP (1) | JP2545000B2 (https=) |
| KR (1) | KR930003116B1 (https=) |
| AR (1) | AR243605A1 (https=) |
| AT (1) | AT400520B (https=) |
| AU (1) | AU633537B2 (https=) |
| BR (1) | BR8907817A (https=) |
| CA (1) | CA2004979A1 (https=) |
| CH (1) | CH681779A5 (https=) |
| DE (2) | DE3991484C2 (https=) |
| DK (1) | DK110791A (https=) |
| EG (1) | EG18822A (https=) |
| ES (1) | ES2051675T3 (https=) |
| FI (1) | FI912784A0 (https=) |
| GB (1) | GB2247404B (https=) |
| GR (1) | GR1000609B (https=) |
| HU (1) | HUT58202A (https=) |
| IE (1) | IE62621B1 (https=) |
| IL (1) | IL92622A (https=) |
| LU (1) | LU87949A1 (https=) |
| LV (1) | LV10303B (https=) |
| MC (1) | MC2171A1 (https=) |
| NO (1) | NO912228L (https=) |
| NZ (1) | NZ231658A (https=) |
| OA (1) | OA09362A (https=) |
| PT (1) | PT92546B (https=) |
| SE (1) | SE505938C2 (https=) |
| WO (1) | WO1990006748A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5298502A (en) * | 1988-12-12 | 1994-03-29 | Fmc Corporation | Method and composition for photodynamic treatment and detection of tumors |
| US5132101A (en) * | 1990-05-04 | 1992-07-21 | Cytopharm, Inc. | Acetylene-cumulene porphycene compounds for photodynamic therapy |
| US5244671A (en) * | 1991-01-29 | 1993-09-14 | Cytopharm, Inc. | Derivatives of porphycene for photodynamic therapy of cancer |
| US5179120A (en) * | 1991-06-28 | 1993-01-12 | Cytopharm, Inc. | Porphycene compounds for photodynamic therapy |
| TW492975B (en) * | 1993-07-26 | 2002-07-01 | Novartis Ag | Tryptase inhibitor |
| GB9318841D0 (en) * | 1993-09-10 | 1993-10-27 | Res Foundation Of The Norwegia | Composition |
| US5939602A (en) * | 1995-06-06 | 1999-08-17 | Novartis Finance Corporation | DNA molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof |
| US6023012A (en) * | 1996-02-28 | 2000-02-08 | Novartis Finance Corporation | DNA molecules encoding plant protoporphyrinogen oxidase |
| US5767373A (en) | 1994-06-16 | 1998-06-16 | Novartis Finance Corporation | Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms |
| US6084155A (en) | 1995-06-06 | 2000-07-04 | Novartis Ag | Herbicide-tolerant protoporphyrinogen oxidase ("protox") genes |
| AU724893B2 (en) * | 1996-02-28 | 2000-10-05 | Syngenta Participations Ag | DNA molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof |
| JPH10330359A (ja) * | 1997-03-31 | 1998-12-15 | Nippon Bayeragrochem Kk | フエニルアセチレン誘導体及び除草剤 |
| DE102005017152B4 (de) * | 2005-04-13 | 2007-02-08 | Lindauer Dornier Gmbh | Verfahren zum Trocknen von vorzugsweise plattenförmigen Produkten und Durchlauftrockner in Mehretagenbauweise |
| EP2443102B1 (en) | 2009-06-19 | 2013-04-17 | Basf Se | Herbicidal benzoxazinones |
| US8445407B2 (en) * | 2009-11-02 | 2013-05-21 | Basf Se | Herbicidal tetrahydrophthalimides |
| EP2621924B1 (en) * | 2010-10-01 | 2015-03-04 | Basf Se | Herbicidal benzoxazinones |
| CA2818034C (en) | 2010-12-15 | 2019-06-18 | Basf Se | Herbicidal compositions comprising a benzoxazinone compound and an n-acylsulfamoylphenylurea safener |
| CN102875569A (zh) * | 2012-09-27 | 2013-01-16 | 南开大学 | 具有除草活性和抗肝癌活性的异噁唑并嘧啶酮(或三嗪酮)类化合物 |
| CN110072853B (zh) * | 2016-12-16 | 2023-07-25 | 巴斯夫欧洲公司 | 除草的苯基三唑啉酮类 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4393071A (en) * | 1975-03-17 | 1983-07-12 | Naoharu Fujii | Method of treating gastric, mammary, lung and uterus tumors |
| US4404019A (en) * | 1980-12-24 | 1983-09-13 | Sumitomo Chemical Company, Limited | 3-Chloro-1-phenyl-1,2,4-triazolin-5-ones and their use as herbicides |
| CH651029A5 (de) * | 1980-12-25 | 1985-08-30 | Nihon Nohyaku Co Ltd | Triazolin-derivate, verfahren zu ihrer herstellung und sie enthaltende herbizide mittel. |
| JPS60190711A (ja) * | 1984-03-09 | 1985-09-28 | Tokyo Tanabe Co Ltd | プロトポルフイリン類注射用製剤 |
| US4761174A (en) * | 1987-04-14 | 1988-08-02 | Fmc Corporation | Triazolin-5-one herbicides |
| US4755217A (en) * | 1987-01-15 | 1988-07-05 | Fmc Corporation | Triazinedione herbicides |
-
1989
- 1989-12-06 NZ NZ231658A patent/NZ231658A/en unknown
- 1989-12-07 IE IE392589A patent/IE62621B1/en not_active IP Right Cessation
- 1989-12-08 CH CH2658/90A patent/CH681779A5/de unknown
- 1989-12-08 WO PCT/US1989/005599 patent/WO1990006748A2/en not_active Ceased
- 1989-12-08 ES ES90901350T patent/ES2051675T3/es not_active Expired - Lifetime
- 1989-12-08 BR BR898907817A patent/BR8907817A/pt not_active Application Discontinuation
- 1989-12-08 DE DE3991484A patent/DE3991484C2/de not_active Expired - Fee Related
- 1989-12-08 HU HU901144A patent/HUT58202A/hu unknown
- 1989-12-08 EP EP90901350A patent/EP0447491B1/en not_active Expired - Lifetime
- 1989-12-08 KR KR1019900701747A patent/KR930003116B1/ko not_active Expired - Fee Related
- 1989-12-08 AT AT0903489A patent/AT400520B/de not_active IP Right Cessation
- 1989-12-08 MC MC89@@D patent/MC2171A1/xx unknown
- 1989-12-08 JP JP2501659A patent/JP2545000B2/ja not_active Expired - Lifetime
- 1989-12-08 FI FI912784A patent/FI912784A0/fi not_active Application Discontinuation
- 1989-12-08 DE DE19893991484 patent/DE3991484T/de active Pending
- 1989-12-08 CA CA002004979A patent/CA2004979A1/en not_active Abandoned
- 1989-12-08 AU AU48222/90A patent/AU633537B2/en not_active Ceased
- 1989-12-10 IL IL9262289A patent/IL92622A/en not_active IP Right Cessation
- 1989-12-11 AR AR89315638A patent/AR243605A1/es active
- 1989-12-12 GR GR890100817A patent/GR1000609B/el unknown
- 1989-12-12 PT PT92546A patent/PT92546B/pt not_active IP Right Cessation
- 1989-12-21 EG EG60989A patent/EG18822A/xx active
-
1991
- 1991-05-15 GB GB9110472A patent/GB2247404B/en not_active Expired - Fee Related
- 1991-06-11 NO NO91912228A patent/NO912228L/no unknown
- 1991-06-11 DK DK110791A patent/DK110791A/da unknown
- 1991-06-12 OA OA60016A patent/OA09362A/xx unknown
- 1991-06-12 LU LU87949A patent/LU87949A1/fr unknown
- 1991-06-12 SE SE9101807A patent/SE505938C2/sv not_active IP Right Cessation
-
1993
- 1993-09-09 LV LVP-93-1060A patent/LV10303B/lv unknown
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