GEP20084421B - Proline derivatives and their use as dipeptidyl peptidase iv inhibitors - Google Patents

Proline derivatives and their use as dipeptidyl peptidase iv inhibitors

Info

Publication number
GEP20084421B
GEP20084421B GEAP20059699A GEAP2005009699A GEP20084421B GE P20084421 B GEP20084421 B GE P20084421B GE AP20059699 A GEAP20059699 A GE AP20059699A GE AP2005009699 A GEAP2005009699 A GE AP2005009699A GE P20084421 B GEP20084421 B GE P20084421B
Authority
GE
Georgia
Prior art keywords
inhibitors
dipeptidyl peptidase
proline derivatives
compounds
peptidase
Prior art date
Application number
GEAP20059699A
Other languages
English (en)
Inventor
Bernard Hulin
David Walter Piotrowski
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34966115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GEP20084421(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of GEP20084421B publication Critical patent/GEP20084421B/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

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  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nutrition Science (AREA)
  • Vascular Medicine (AREA)
GEAP20059699A 2004-05-12 2005-04-29 Proline derivatives and their use as dipeptidyl peptidase iv inhibitors GEP20084421B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57030004P 2004-05-12 2004-05-12
US66430505P 2005-03-21 2005-03-21

Publications (1)

Publication Number Publication Date
GEP20084421B true GEP20084421B (en) 2008-07-10

Family

ID=34966115

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP20059699A GEP20084421B (en) 2004-05-12 2005-04-29 Proline derivatives and their use as dipeptidyl peptidase iv inhibitors

Country Status (36)

Country Link
US (4) US7291618B2 (enExample)
EP (2) EP2116541B1 (enExample)
JP (1) JP4227660B2 (enExample)
KR (1) KR100869616B1 (enExample)
AP (1) AP2320A (enExample)
AR (1) AR049894A1 (enExample)
AT (1) ATE437870T1 (enExample)
AU (1) AU2005247684B2 (enExample)
BR (1) BRPI0510284A (enExample)
CA (1) CA2566108C (enExample)
CR (1) CR8744A (enExample)
CY (1) CY1109322T1 (enExample)
DE (1) DE602005015699D1 (enExample)
DK (1) DK1753748T3 (enExample)
EA (1) EA011086B9 (enExample)
EC (1) ECSP066985A (enExample)
ES (1) ES2327857T3 (enExample)
GE (1) GEP20084421B (enExample)
HR (1) HRP20090471T1 (enExample)
IL (1) IL178339A (enExample)
MA (1) MA28578B1 (enExample)
MX (1) MXPA06013114A (enExample)
MY (1) MY139805A (enExample)
NL (1) NL1029015C2 (enExample)
NO (1) NO20064400L (enExample)
NZ (1) NZ550229A (enExample)
PA (1) PA8632701A1 (enExample)
PE (1) PE20060316A1 (enExample)
PL (1) PL1753748T3 (enExample)
PT (1) PT1753748E (enExample)
RS (1) RS51106B (enExample)
SI (1) SI1753748T1 (enExample)
SV (1) SV2006002110A (enExample)
TW (1) TWI347322B (enExample)
UY (1) UY28892A1 (enExample)
WO (1) WO2005116014A1 (enExample)

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WO2006073167A1 (ja) * 2005-01-07 2006-07-13 Ono Pharmaceutical Co., Ltd. ピロリジン誘導体
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
PE20071221A1 (es) 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
KR20090004950A (ko) 2006-04-12 2009-01-12 프로비오드룩 아게 효소 억제제
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
SG174054A1 (en) 2006-05-04 2011-09-29 Boehringer Ingelheim Int Polymorphs
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
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