GB8531071D0 - Therapeutic compound - Google Patents

Therapeutic compound

Info

Publication number
GB8531071D0
GB8531071D0 GB858531071A GB8531071A GB8531071D0 GB 8531071 D0 GB8531071 D0 GB 8531071D0 GB 858531071 A GB858531071 A GB 858531071A GB 8531071 A GB8531071 A GB 8531071A GB 8531071 D0 GB8531071 D0 GB 8531071D0
Authority
GB
United Kingdom
Prior art keywords
therapeutic compound
cyclobutyl
chlorophenyl
depression
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB858531071A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10589895&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB8531071(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to GB858531071A priority Critical patent/GB8531071D0/en
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of GB8531071D0 publication Critical patent/GB8531071D0/en
Priority to IE310286A priority patent/IE59429B1/en
Priority to IN921/MAS/86A priority patent/IN163129B/en
Priority to ZA869078A priority patent/ZA869078B/xx
Priority to SI8612050A priority patent/SI8612050A8/sl
Priority to YU205086A priority patent/YU46033B/sh
Priority to PH34552A priority patent/PH22481A/en
Priority to DK585786A priority patent/DK170770B1/da
Priority to AT86309631T priority patent/ATE56942T1/de
Priority to EP86309631A priority patent/EP0230742B1/en
Priority to IL80934A priority patent/IL80934A/xx
Priority to NZ218578A priority patent/NZ218578A/xx
Priority to ES86309631T priority patent/ES2018163T4/es
Priority to GB8629568A priority patent/GB2184122B/en
Priority to FI865030A priority patent/FI90413C/fi
Priority to DE8686309631T priority patent/DE3674570D1/de
Priority to AU66442/86A priority patent/AU601167B2/en
Priority to UA4028642A priority patent/UA7206A1/uk
Priority to SU4028642A priority patent/SU1443796A3/ru
Priority to CS869305A priority patent/CS259545B2/cs
Priority to DD86297631A priority patent/DD263050A5/de
Priority to MX468486A priority patent/MX4684A/es
Priority to JP61299806A priority patent/JPS62155240A/ja
Priority to KR1019860010764A priority patent/KR940008913B1/ko
Priority to HU865232A priority patent/HU201901B/hu
Priority to PL1986263020A priority patent/PL149519B1/pl
Priority to NO865093A priority patent/NO165540C/no
Priority to CA000525648A priority patent/CA1266278A/en
Priority to EG774/86A priority patent/EG17770A/xx
Priority to CN86108547A priority patent/CN1016245B/zh
Priority to PT83958A priority patent/PT83958B/pt
Priority to US07/342,638 priority patent/US4929629A/en
Priority to US07/467,471 priority patent/US5068440A/en
Priority to GR90400895T priority patent/GR3001069T3/el
Priority to HRP-2050/86A priority patent/HRP930745B1/xx
Priority to LTRP1012A priority patent/LT2520B/xx
Priority to LV931268A priority patent/LV5455A3/xx
Priority to GEAP19941745A priority patent/GEP19970812B/en
Priority to NL300065C priority patent/NL300065I1/nl
Priority to LU90865C priority patent/LU90865I2/fr
Priority to NO2005022C priority patent/NO2005022I1/no
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
GB858531071A 1985-12-17 1985-12-17 Therapeutic compound Pending GB8531071D0 (en)

Priority Applications (41)

Application Number Priority Date Filing Date Title
GB858531071A GB8531071D0 (en) 1985-12-17 1985-12-17 Therapeutic compound
IE310286A IE59429B1 (en) 1985-12-17 1986-11-25 N,N-dimethyl-1-(1-(4-chlorophenyl) cyclobutyl)-3-methyl butylamine hydrochloride monohydrate
IN921/MAS/86A IN163129B (https=) 1985-12-17 1986-11-28
ZA869078A ZA869078B (en) 1985-12-17 1986-12-02 Therapeutic compound
SI8612050A SI8612050A8 (sl) 1985-12-17 1986-12-02 Nova nehigroskopična oblika n,n-dimetil-1-1-(4-klorofenil) ciklobutil -3-metilbutilamin klorhidrata
YU205086A YU46033B (sh) 1985-12-17 1986-12-02 Novi henigroskopni oblikn,n-dimetil-1-/1-(4-hlorofenil) ciklobutil/-3-metilbuti lamin hlorhidrata
PH34552A PH22481A (en) 1985-12-17 1986-12-04 N,n-dimethyl-1-/-(4-chlorophenyl) cyclobutyl/-3-methylbuttlamine hydrochloride monhydrate, composition thereof and method of use
DK585786A DK170770B1 (da) 1985-12-17 1986-12-05 N,N-Dimetyl-1-[1-(4-(klorfenyl)-cyklobutyl]-3-metylbutylamin-hydroklorid, monohydrat, fremgangsmåde til fremstilling deraf, farmaceutisk præparat indeholdende forbindelsen samt anvendelse deraf.
DE8686309631T DE3674570D1 (de) 1985-12-17 1986-12-10 N,n-dimethyl-1-(1-(4-chlorophenyl)-cyclobutyl)-3-methylbutylamin-hydrochlorid, monohydrat und pharmazeutische zusammensetzungen, welche diese enthalten.
FI865030A FI90413C (fi) 1985-12-17 1986-12-10 Menetelmä terapeuttisesti käyttökelpoisen N,N-dimetyyli-1-/1-(4-kloorifenyyli)-syklobutyyli/-3-metyylibutyyliamiinihydrokloridimonohydraatin valmistamiseksi
EP86309631A EP0230742B1 (en) 1985-12-17 1986-12-10 N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride monohydrate and pharmaceutical compositions containing it
AT86309631T ATE56942T1 (de) 1985-12-17 1986-12-10 N,n-dimethyl-1-(1-(4-chlorophenyl)-cyclobutyl>- methylbutylamin-hydrochlorid, monohydrat und pharmazeutische zusammensetzungen, welche diese enthalten.
IL80934A IL80934A (en) 1985-12-17 1986-12-10 N,n-dimethyl-1-(1-(4-chlorophenyl)cyclobutyl)-3-methylbutylamine hydrochloride monohydrate,process for its preparation and antidepressive compositions containing it
NZ218578A NZ218578A (en) 1985-12-17 1986-12-10 N,n-dimethyl-1-(1-(4-chlorophenyl)cyclobutyl)-3-methyl butylamine hydrochloride monohydrate and pharmaceutical compositions
ES86309631T ES2018163T4 (es) 1985-12-17 1986-12-10 Un procedimiento para preparar hidrocloruro de N,N - dimetil - 1 - [(1 - (4 - clorofenil) ciclobutil ] - 3 - metilbutilamina monohidrato
GB8629568A GB2184122B (en) 1985-12-17 1986-12-10 N,n-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methyl butylamine hydrochloride monohydrate
AU66442/86A AU601167B2 (en) 1985-12-17 1986-12-11 Pharmaceutical compositions containing N,N-dimethyl-1-(1- (4-chlorophenyl)-cyclobutyl)-3-methylbutylamine hydrochloride monohydrate
UA4028642A UA7206A1 (uk) 1985-12-17 1986-12-15 Спосіб одержання гідрохлориду n,n-діметіл-1-[1-(4-хлорфеніл)-циклобутіл]-3-метілбутіламіна у вигляді моногідрату
SU4028642A SU1443796A3 (ru) 1985-12-17 1986-12-15 Способ получени гидрохлорида N,N-диметил-1- @ 1-(4-хлорфенил)-циклобутил @ -3-метилбутиламина в виде моногидрата
CS869305A CS259545B2 (en) 1985-12-17 1986-12-15 Method of n,n-dimethyl-1-(1-/chlorphenyl/ cyclobutyl)-3-methylbutyl-amin-hydrochloride's monohydrate production
DD86297631A DD263050A5 (de) 1985-12-17 1986-12-15 Verfahren zur herstellung von n,n-dimethyl-1-[1-(4-chlorphenyl)-cyclobutyl]-3-methylbutylamin-hydrochlorid-monohydrat
MX468486A MX4684A (es) 1985-12-17 1986-12-16 Clorohidrato de n,n-dimetil-1-(1-(4-clorofenil)ciclobutil)-3-metilbutilamina y proceso para su preparacion.
NO865093A NO165540C (no) 1985-12-17 1986-12-16 Analogifremgangsmaate for fremstilling av den terapeutisk aktive forbindelse n,n-dimetyl-1-(1-(4-klorfenyl)cyklobutyl)-3-metylbutylamin-hydroklorid-monohydrat.
JP61299806A JPS62155240A (ja) 1985-12-17 1986-12-16 治療用化合物
PL1986263020A PL149519B1 (en) 1985-12-17 1986-12-16 Method for manufacturing n,n-dimethyl-1-/1-(4-chlorphenyl)cyclobutyl/-3-methylbutyl amine hydrochloride monohydrate
KR1019860010764A KR940008913B1 (ko) 1985-12-17 1986-12-16 N,n-디메틸-1-[1-(4-클로로페닐)-사이클로부틸]-3-메틸부틸아민 염산염 일수화물의 제조방법
HU865232A HU201901B (en) 1985-12-17 1986-12-16 Process for producing n,n-dimethyl-1-(1-)4-chloro-phenyl(-cyclobutyl)-3-methyl-butyl-amine-hydrochloride-monohydrate
CA000525648A CA1266278A (en) 1985-12-17 1986-12-17 Therapeutic compound
EG774/86A EG17770A (en) 1985-12-17 1986-12-17 A process for the preparation of therapeutic compound which is useful in the treatment of depression
CN86108547A CN1016245B (zh) 1985-12-17 1986-12-17 N，n-二甲基-1-[1-(4-氯苯基)环丁基]-3-甲基丁胺盐酸盐-水合物的制备方法
PT83958A PT83958B (pt) 1985-12-17 1986-12-17 Processo de preparacao de mono-hidrato do hidrocloreto de n,n-dimetil-1-{1-(4-clorofenil)ciclobutil}-3-metilbutilamina
US07/342,638 US4929629A (en) 1985-12-17 1989-04-19 Therapeutic compound
US07/467,471 US5068440A (en) 1985-12-17 1990-01-19 Process for the manufacture of N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride monohydrate
GR90400895T GR3001069T3 (en) 1985-12-17 1990-11-08 N,n-dimethyl-1-(1-(4-chlorophenyl)cyclobutyl)-3-methylbutylamine hydrochloride monohydrate and pharmaceutical compositions containing it
HRP-2050/86A HRP930745B1 (en) 1985-12-17 1993-04-02 New non-hygroscopic form of n,n-dimethyl-1-/1-(4-chlorophenyl) cyclobuthyl)-3-methylbutylamine hydrochloride
LTRP1012A LT2520B (lt) 1985-12-17 1993-09-20 N,n-dimetil-1(1-(4-chlorfenil)-ciklobutil)-3-m etilbutilamino hidrochlorido monohidrato gavimo budas
LV931268A LV5455A3 (lv) 1985-12-17 1993-11-25 N,N-dimetil-1-Ú1-(4-hlorfenil)-ciklobutil¾-3-metilbutilamina hidrohlorida monohidrata iegusanas metode
GEAP19941745A GEP19970812B (en) 1985-12-17 1994-01-20 New non-hygroscopic form of n,n-dimethyl-1-/1-(4-chlorophenyl) cyclobuthyl)-3-methylbutylamine hydrochloride
NL300065C NL300065I1 (nl) 1985-12-17 2001-10-04 N,N-dimethyl-1Ä1-(4-chloorfenyl)cyclobutylÜ-3-methylbutylamine-hydrochloride, monohydraat en farmaceutische preparaten, die deze bevatten.
LU90865C LU90865I2 (fr) 1985-12-17 2001-12-18 Hydrochlorure d sibutramine ses d-riv-s et ses sels pharmaceutiquement acceptables en particulier le monohydrate d'hydrochlorure de sibutramine
NO2005022C NO2005022I1 (no) 1985-12-17 2005-09-14 N-Dimetyl-1-(1-(4-klorfenyl)cyklobutylÜ-3-metylbutylamin (sibutramin hydroklorid)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858531071A GB8531071D0 (en) 1985-12-17 1985-12-17 Therapeutic compound

Publications (1)

Publication Number Publication Date
GB8531071D0 true GB8531071D0 (en) 1986-01-29

Family

ID=10589895

Family Applications (1)

Application Number Title Priority Date Filing Date
GB858531071A Pending GB8531071D0 (en) 1985-12-17 1985-12-17 Therapeutic compound

Country Status (34)

Country Link
US (2) US4929629A (https=)
EP (1) EP0230742B1 (https=)
JP (1) JPS62155240A (https=)
KR (1) KR940008913B1 (https=)
CN (1) CN1016245B (https=)
AT (1) ATE56942T1 (https=)
AU (1) AU601167B2 (https=)
CA (1) CA1266278A (https=)
CS (1) CS259545B2 (https=)
DD (1) DD263050A5 (https=)
DE (1) DE3674570D1 (https=)
DK (1) DK170770B1 (https=)
EG (1) EG17770A (https=)
ES (1) ES2018163T4 (https=)
FI (1) FI90413C (https=)
GB (1) GB8531071D0 (https=)
GE (1) GEP19970812B (https=)
GR (1) GR3001069T3 (https=)
HU (1) HU201901B (https=)
IE (1) IE59429B1 (https=)
IL (1) IL80934A (https=)
IN (1) IN163129B (https=)
LU (1) LU90865I2 (https=)
MX (1) MX4684A (https=)
NL (1) NL300065I1 (https=)
NO (2) NO165540C (https=)
NZ (1) NZ218578A (https=)
PH (1) PH22481A (https=)
PL (1) PL149519B1 (https=)
PT (1) PT83958B (https=)
SU (1) SU1443796A3 (https=)
UA (1) UA7206A1 (https=)
YU (1) YU46033B (https=)
ZA (1) ZA869078B (https=)

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US5459164A (en) * 1994-02-03 1995-10-17 Boots Pharmaceuticals, Inc. Medical treatment
DE4443891A1 (de) * 1994-12-09 1996-06-13 Bayer Ag Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide
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EP0230742B1 (en) 1990-09-26
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FI865030L (fi) 1987-06-18
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UA7206A1 (uk) 1995-06-30
AU601167B2 (en) 1990-09-06
NO165540B (no) 1990-11-19
CN1016245B (zh) 1992-04-15
DK170770B1 (da) 1996-01-15
MX4684A (es) 1993-12-01
DE3674570D1 (de) 1990-10-31
NO165540C (no) 1991-02-27
KR940008913B1 (ko) 1994-09-28
US5068440A (en) 1991-11-26
ATE56942T1 (de) 1990-10-15
FI90413B (fi) 1993-10-29
IE59429B1 (en) 1994-02-23
CS259545B2 (en) 1988-10-14
CN86108547A (zh) 1987-08-19
PT83958A (en) 1987-01-01
SU1443796A3 (ru) 1988-12-07
FI90413C (fi) 1994-02-10
HUT45964A (en) 1988-09-28
CS930586A2 (en) 1988-02-15
EG17770A (en) 1991-03-30
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YU205086A (en) 1987-12-31
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HU201901B (en) 1991-01-28
YU46033B (sh) 1992-12-21
JPH0144176B2 (https=) 1989-09-26
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IL80934A (en) 1990-07-26
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IE863102L (en) 1987-06-17
DK585786A (da) 1987-06-18
NO865093D0 (no) 1986-12-16
PL149519B1 (en) 1990-02-28
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JPS62155240A (ja) 1987-07-10
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DK585786D0 (da) 1986-12-05
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PT83958B (pt) 1989-05-12
AU6644286A (en) 1987-06-18
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US4929629A (en) 1990-05-29
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PH22481A (en) 1988-09-12
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