PT83958B - Processo de preparacao de mono-hidrato do hidrocloreto de n,n-dimetil-1-{1-(4-clorofenil)ciclobutil}-3-metilbutilamina - Google Patents

Processo de preparacao de mono-hidrato do hidrocloreto de n,n-dimetil-1-{1-(4-clorofenil)ciclobutil}-3-metilbutilamina

Info

Publication number
PT83958B
PT83958B PT83958A PT8395886A PT83958B PT 83958 B PT83958 B PT 83958B PT 83958 A PT83958 A PT 83958A PT 8395886 A PT8395886 A PT 8395886A PT 83958 B PT83958 B PT 83958B
Authority
PT
Portugal
Prior art keywords
cyclobutyl
chlorophenyl
dimethyl
preparation process
methylbutylamine hydrochloride
Prior art date
Application number
PT83958A
Other languages
English (en)
Other versions
PT83958A (en
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10589895&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT83958(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of PT83958A publication Critical patent/PT83958A/pt
Publication of PT83958B publication Critical patent/PT83958B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
PT83958A 1985-12-17 1986-12-17 Processo de preparacao de mono-hidrato do hidrocloreto de n,n-dimetil-1-{1-(4-clorofenil)ciclobutil}-3-metilbutilamina PT83958B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858531071A GB8531071D0 (en) 1985-12-17 1985-12-17 Therapeutic compound

Publications (2)

Publication Number Publication Date
PT83958A PT83958A (en) 1987-01-01
PT83958B true PT83958B (pt) 1989-05-12

Family

ID=10589895

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83958A PT83958B (pt) 1985-12-17 1986-12-17 Processo de preparacao de mono-hidrato do hidrocloreto de n,n-dimetil-1-{1-(4-clorofenil)ciclobutil}-3-metilbutilamina

Country Status (34)

Country Link
US (2) US4929629A (pt)
EP (1) EP0230742B1 (pt)
JP (1) JPS62155240A (pt)
KR (1) KR940008913B1 (pt)
CN (1) CN1016245B (pt)
AT (1) ATE56942T1 (pt)
AU (1) AU601167B2 (pt)
CA (1) CA1266278A (pt)
CS (1) CS259545B2 (pt)
DD (1) DD263050A5 (pt)
DE (1) DE3674570D1 (pt)
DK (1) DK170770B1 (pt)
EG (1) EG17770A (pt)
ES (1) ES2018163T4 (pt)
FI (1) FI90413C (pt)
GB (1) GB8531071D0 (pt)
GE (1) GEP19970812B (pt)
GR (1) GR3001069T3 (pt)
HU (1) HU201901B (pt)
IE (1) IE59429B1 (pt)
IL (1) IL80934A (pt)
IN (1) IN163129B (pt)
LU (1) LU90865I2 (pt)
MX (1) MX4684A (pt)
NL (1) NL300065I1 (pt)
NO (2) NO165540C (pt)
NZ (1) NZ218578A (pt)
PH (1) PH22481A (pt)
PL (1) PL149519B1 (pt)
PT (1) PT83958B (pt)
SU (1) SU1443796A3 (pt)
UA (1) UA7206A1 (pt)
YU (1) YU46033B (pt)
ZA (1) ZA869078B (pt)

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GB8704777D0 (en) * 1987-02-28 1987-04-01 Boots Co Plc Medical treatment
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JPH08500093A (ja) * 1992-06-23 1996-01-09 セプラコア インコーポレーテッド 光学的に純粋な(−)シブトラミンを用いるうつ病およびその他の障害を治療する方法ならびに組成物
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DE4443891A1 (de) 1994-12-09 1996-06-13 Bayer Ag Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide
GB9619757D0 (en) * 1996-09-21 1996-11-06 Knoll Ag Chemical process
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GB9727131D0 (en) 1997-12-24 1998-02-25 Knoll Ag Therapeutic agents
US6476078B2 (en) * 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
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AU3895400A (en) 1999-03-19 2000-10-09 Knoll Pharmaceutical Company Control of metabolism
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DE60019914T2 (de) 1999-03-19 2006-05-04 Abbott Gmbh & Co. Kg Verwendung von Sibutramin oder dessem Derivat zur Behandlung von Schlafstörungen
WO2000056308A1 (en) 1999-03-19 2000-09-28 Knoll Pharmaceutical Company Prevention of cardiovascular disease
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AU3894600A (en) 1999-03-19 2000-10-09 Knoll Pharmaceutical Company Method of treating sexual dysfunction
JP2002539250A (ja) 1999-03-19 2002-11-19 クノール・ゲー・エム・ベー・ハー 肺高血圧症の治療
US6552087B1 (en) 1999-03-19 2003-04-22 Abbott Gmbh & Co. Kg Therapeutic agent comprising (+)-sibutramine
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US6562974B2 (en) 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
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Also Published As

Publication number Publication date
NO165540B (no) 1990-11-19
KR870005961A (ko) 1987-07-08
ES2018163T4 (es) 2012-06-14
GR3001069T3 (en) 1992-03-20
LU90865I2 (fr) 2002-02-18
CS259545B2 (en) 1988-10-14
FI865030A0 (fi) 1986-12-10
PL149519B1 (en) 1990-02-28
AU601167B2 (en) 1990-09-06
IL80934A (en) 1990-07-26
DE3674570D1 (de) 1990-10-31
EG17770A (en) 1991-03-30
IE863102L (en) 1987-06-17
PL263020A1 (en) 1988-05-12
NO2005022I1 (no) 2005-10-03
JPH0144176B2 (pt) 1989-09-26
AU6644286A (en) 1987-06-18
EP0230742B1 (en) 1990-09-26
NO165540C (no) 1991-02-27
GB8531071D0 (en) 1986-01-29
GEP19970812B (en) 1997-02-10
ATE56942T1 (de) 1990-10-15
DK585786A (da) 1987-06-18
UA7206A1 (uk) 1995-06-30
PH22481A (en) 1988-09-12
PT83958A (en) 1987-01-01
US5068440A (en) 1991-11-26
DD263050A5 (de) 1988-12-21
IN163129B (pt) 1988-08-13
FI90413C (fi) 1994-02-10
HUT45964A (en) 1988-09-28
FI865030A (fi) 1987-06-18
HU201901B (en) 1991-01-28
DK585786D0 (da) 1986-12-05
MX4684A (es) 1993-12-01
FI90413B (fi) 1993-10-29
IE59429B1 (en) 1994-02-23
ES2018163B3 (es) 1991-04-01
JPS62155240A (ja) 1987-07-10
NO865093L (no) 1987-06-18
DK170770B1 (da) 1996-01-15
NL300065I1 (nl) 2001-12-01
CN1016245B (zh) 1992-04-15
KR940008913B1 (ko) 1994-09-28
EP0230742A1 (en) 1987-08-05
CA1266278A (en) 1990-02-27
ZA869078B (en) 1987-07-29
SU1443796A3 (ru) 1988-12-07
US4929629A (en) 1990-05-29
CS930586A2 (en) 1988-02-15
NZ218578A (en) 1989-04-26
YU205086A (en) 1987-12-31
YU46033B (sh) 1992-12-21
CN86108547A (zh) 1987-08-19
NO865093D0 (no) 1986-12-16

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