GB1531558A - Compositions having affinity for hepatitis virus and method for hepatitis virus removal - Google Patents

Compositions having affinity for hepatitis virus and method for hepatitis virus removal

Info

Publication number
GB1531558A
GB1531558A GB28533/76A GB2853376A GB1531558A GB 1531558 A GB1531558 A GB 1531558A GB 28533/76 A GB28533/76 A GB 28533/76A GB 2853376 A GB2853376 A GB 2853376A GB 1531558 A GB1531558 A GB 1531558A
Authority
GB
United Kingdom
Prior art keywords
hepatitis virus
affinity
compositions
removal
july
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28533/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phadia AB
Original Assignee
Kabi AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE7507854A external-priority patent/SE417613B/xx
Priority claimed from SE7605632A external-priority patent/SE421076B/xx
Application filed by Kabi AB filed Critical Kabi AB
Publication of GB1531558A publication Critical patent/GB1531558A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10151Methods of production or purification of viral material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/82Hepatitis associated antigens and antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/825Pretreatment for removal of interfering factors from sample
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/826Viruses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/829Blood
    • Y10S530/83Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GB28533/76A 1975-07-09 1976-07-08 Compositions having affinity for hepatitis virus and method for hepatitis virus removal Expired GB1531558A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE7507854A SE417613B (sv) 1975-07-09 1975-07-09 Forfarande for separation eller koncentrering av hepatitvirus ur blandningar av biologiskt material
SE7605632A SE421076B (sv) 1976-05-18 1976-05-18 Forfarande for separation eller koncentrering av hepatitvirus ur blandningar av biologiskt material

Publications (1)

Publication Number Publication Date
GB1531558A true GB1531558A (en) 1978-11-08

Family

ID=26656635

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28533/76A Expired GB1531558A (en) 1975-07-09 1976-07-08 Compositions having affinity for hepatitis virus and method for hepatitis virus removal

Country Status (20)

Country Link
US (1) US4168300A (US20080094685A1-20080424-C00004.png)
JP (1) JPS5210416A (US20080094685A1-20080424-C00004.png)
AT (1) AT355215B (US20080094685A1-20080424-C00004.png)
AU (1) AU510068B2 (US20080094685A1-20080424-C00004.png)
CA (1) CA1076956A (US20080094685A1-20080424-C00004.png)
CH (1) CH630115A5 (US20080094685A1-20080424-C00004.png)
CS (1) CS223818B2 (US20080094685A1-20080424-C00004.png)
DE (1) DE2630753A1 (US20080094685A1-20080424-C00004.png)
DK (1) DK148874C (US20080094685A1-20080424-C00004.png)
ES (1) ES449670A1 (US20080094685A1-20080424-C00004.png)
FI (1) FI55868C (US20080094685A1-20080424-C00004.png)
FR (1) FR2317309A1 (US20080094685A1-20080424-C00004.png)
GB (1) GB1531558A (US20080094685A1-20080424-C00004.png)
IE (1) IE43952B1 (US20080094685A1-20080424-C00004.png)
IL (1) IL49752A (US20080094685A1-20080424-C00004.png)
IT (1) IT1062511B (US20080094685A1-20080424-C00004.png)
NL (1) NL7607647A (US20080094685A1-20080424-C00004.png)
NO (1) NO148339C (US20080094685A1-20080424-C00004.png)
NZ (1) NZ181384A (US20080094685A1-20080424-C00004.png)
PL (1) PL105363B1 (US20080094685A1-20080424-C00004.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2140424A (en) * 1983-04-06 1984-11-28 Asahi Chemical Ind An adsorbent for absorbing thereonto an autoantibody and/or immune complexes from a body fluid

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE420977B (sv) * 1976-03-18 1981-11-16 Kabi Ab Forfarande for rening och isolering av hepatitvirus for vaccinframstellning
SE452336B (sv) * 1978-06-16 1987-11-23 Boehringer Mannheim Gmbh Forfarande for pavisning av sjukdomsalstrande mikroorganismer vilka adsorberats extrakorporalt pa en selektivt bindande adsorbent
US4282315A (en) * 1979-09-13 1981-08-04 Corning Glass Works Preparation of enriched whole virus radioligand
US4282287A (en) * 1980-01-24 1981-08-04 Giese Roger W Biochemical avidin-biotin multiple-layer system
US4478914B1 (en) * 1980-01-24 1997-06-17 Roger W Giese Process for applying multiple layers of a protein and a ligand extender to a surface and to the multiple layer system
USRE31712E (en) * 1980-01-24 1984-10-23 Biochemical avidin-biotin multiple-layer system
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
US4411795A (en) * 1980-03-10 1983-10-25 Baxter Travenol Laboratories, Inc. Particle adsorption
US4381239A (en) * 1981-02-10 1983-04-26 Tanabe Seiyaku Co., Ltd. Method for reducing the pyrogen content of or removing pyrogens from substances contaminated therewith
US4488969A (en) * 1982-02-09 1984-12-18 Amf Incorporated Fibrous media containing millimicron-sized particulates
US4511473A (en) * 1982-02-09 1985-04-16 Amf Incorporated Fibrous media containing millimicron-sized particulates
US4596660A (en) * 1982-07-23 1986-06-24 Amf Inc. Fibrous media containing millimicron-sized particulates
US4434093A (en) 1982-07-26 1984-02-28 Ortho Diagnostic Systems Inc. Methods for preparation of HBs Ag free gamma globulins
JPS5961887U (ja) * 1982-10-15 1984-04-23 三菱化学株式会社 コ−クス自動選別装置
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen
EP0151108A1 (en) * 1983-05-31 1985-08-14 Baxter Travenol Laboratories, Inc. Particle adsorption
US4764369A (en) * 1983-07-14 1988-08-16 New York Blood Center Inc. Undenatured virus-free biologically active protein derivatives
US4820805A (en) * 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
AU571078B2 (en) * 1984-04-14 1988-03-31 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Purification of filamentous hemagglutinin
JPS6147185A (ja) * 1984-08-09 1986-03-07 Chemo Sero Therapeut Res Inst 日本脳炎ウイルスの精製方法
JPS6147186A (ja) * 1984-08-09 1986-03-07 Chemo Sero Therapeut Res Inst インフルエンザウイルスの精製方法
JPS6147187A (ja) * 1984-08-10 1986-03-07 Chemo Sero Therapeut Res Inst 狂犬病ウイルスの精製方法
JPS61103895A (ja) * 1984-10-26 1986-05-22 Green Cross Corp:The HBsAgの精製方法
CA1244349A (en) * 1985-06-26 1988-11-08 Jen-Chang Hsia Purification of hemoglobin and modified hemoglobin by affinity chromatography
ATE78598T1 (de) * 1987-01-21 1992-08-15 Abbott Lab Immunassay unter benutzung der mikropartikelneutralisierung.
US4869826A (en) * 1987-09-01 1989-09-26 Process Biotechnology, Inc. Cellular adsorbents for removal of viral contaminants from blood and complex protein solutions
JP2729484B2 (ja) * 1988-04-28 1998-03-18 株式会社ミドリ十字 アンチトロンビン−▲iii▼の精製方法
JP2852307B2 (ja) * 1989-02-09 1999-02-03 吉富製薬株式会社 ウイルスの除去された蛋白質製剤の製造法
US5274081A (en) * 1989-09-20 1993-12-28 Immuno A.G. Complex suitable for carrying out a method of purifying pre-S hepatitis B surface antigen
US5576175A (en) * 1989-09-20 1996-11-19 Immuno Aktiengesellschaft Complex suitable for carrying out a method of purifying pre-S hepatitis B surface antigen
US5076933A (en) * 1990-06-29 1991-12-31 Coulter Corporation Process and apparatus for removal of dna and viruses
US5221483A (en) * 1990-06-29 1993-06-22 Coulter Corporation Process and apparatus for removal of DNA, viruses and endotoxins
WO1998008603A1 (en) * 1996-08-30 1998-03-05 Upfront Chromatography A/S Isolation of immunoglobulins
CA2721409A1 (en) * 2008-04-25 2009-10-29 Can Ozbal Separation cartridges and methods for fabrication and use thereof
CN106138851A (zh) * 2016-09-08 2016-11-23 四川聚豪生物科技有限公司 一种可有效治疗乙肝的汤剂药物及其制备方法
CN109896976B (zh) * 2019-02-27 2022-07-12 宁波大学 一种十六代酰肼羧酸钠引发剂及其制备与使用方法
CN109867737B (zh) * 2019-02-27 2022-03-18 宁波大学 一种双子型酰肼阴离子引发剂及其制备与使用方法

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Publication number Priority date Publication date Assignee Title
US3425962A (en) * 1966-12-28 1969-02-04 Bristol Myers Co Salt of a diethylaminoethyl cross-linked dextran anion exchanger
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
GB1392181A (en) * 1971-04-16 1975-04-30 Rech Et Dapplications Soc Gen Fixation of nitrogenous materials
US3852157A (en) * 1971-05-14 1974-12-03 Syva Corp Compounds for enzyme amplification assay
SE361320B (US20080094685A1-20080424-C00004.png) * 1972-03-14 1973-10-29 Exploaterings Ab Tbf
JPS5533442B2 (US20080094685A1-20080424-C00004.png) * 1972-09-14 1980-08-30
ZA74350B (en) * 1973-01-30 1974-11-27 Baxter Laboratories Inc Fractionation of blood
SE413986B (sv) * 1973-03-23 1980-07-07 Exploaterings Ab Tbf Sett att separera amfipatiska emnen innehallande bade hydrofila och hydrofoba grupper samt gelprodukt for genomforande av separationen
US3951937A (en) * 1973-12-20 1976-04-20 The Community Blood Council Of Greater New York, Inc. Large scale purification of hepatitis type B antigen using polyethylene glycol
US3994870A (en) * 1974-01-31 1976-11-30 The Community Blood Council Of Greater New York, Inc. Purification of hepatitis B surface antigen
CS171963B1 (US20080094685A1-20080424-C00004.png) * 1974-02-01 1976-11-29
US4000098A (en) * 1974-08-16 1976-12-28 Palo Alto Medical Research Foundation Separation of proteins by hydrophobic adsorption
US3992517A (en) * 1975-02-19 1976-11-16 Pfizer Inc. Detection of hepatitis B surface antigen by latex agglutination
US3976767A (en) * 1975-04-14 1976-08-24 The New York Blood Center Purification of hepatitis B surface antigen by chromatography on agarose containing aminoalkyl residues

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2140424A (en) * 1983-04-06 1984-11-28 Asahi Chemical Ind An adsorbent for absorbing thereonto an autoantibody and/or immune complexes from a body fluid

Also Published As

Publication number Publication date
NO148339C (no) 1983-09-21
FI55868B (fi) 1979-06-29
DE2630753C2 (US20080094685A1-20080424-C00004.png) 1989-01-19
IE43952L (en) 1977-01-09
FI761997A (US20080094685A1-20080424-C00004.png) 1977-01-10
AU1568476A (en) 1978-01-12
AT355215B (de) 1980-02-25
IE43952B1 (en) 1981-07-15
DK308476A (da) 1977-01-10
AU510068B2 (en) 1980-06-05
ATA500576A (de) 1979-07-15
NZ181384A (en) 1978-12-18
PL191019A1 (pl) 1978-04-24
FI55868C (fi) 1979-10-10
US4168300A (en) 1979-09-18
NL7607647A (nl) 1977-01-11
NO148339B (no) 1983-06-13
PL105363B1 (pl) 1979-10-31
IL49752A (en) 1979-07-25
FR2317309A1 (fr) 1977-02-04
CA1076956A (en) 1980-05-06
FR2317309B1 (US20080094685A1-20080424-C00004.png) 1979-06-01
NO762392L (US20080094685A1-20080424-C00004.png) 1977-01-11
ES449670A1 (es) 1978-02-01
IL49752A0 (en) 1976-08-31
DK148874B (da) 1985-11-04
CS223818B2 (en) 1983-11-25
IT1062511B (it) 1984-10-20
CH630115A5 (de) 1982-05-28
DK148874C (da) 1986-04-14
JPS641444B2 (US20080094685A1-20080424-C00004.png) 1989-01-11
JPS5210416A (en) 1977-01-26
DE2630753A1 (de) 1977-01-20

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940708