ATE130198T1 - Herstellung eines virus und reinigung von virenüberzugsproteinen zur impfstoffverwendung. - Google Patents

Herstellung eines virus und reinigung von virenüberzugsproteinen zur impfstoffverwendung.

Info

Publication number
ATE130198T1
ATE130198T1 AT90909595T AT90909595T ATE130198T1 AT E130198 T1 ATE130198 T1 AT E130198T1 AT 90909595 T AT90909595 T AT 90909595T AT 90909595 T AT90909595 T AT 90909595T AT E130198 T1 ATE130198 T1 AT E130198T1
Authority
AT
Austria
Prior art keywords
virus
purification
preparation
vaccine use
coating proteins
Prior art date
Application number
AT90909595T
Other languages
English (en)
Inventor
Mary Elizabeth Ewasyshyn
Barry Ian Caplan
Anne-Marie Bonneau
Michel Henri Klein
Original Assignee
Connaught Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10659282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE130198(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Connaught Lab filed Critical Connaught Lab
Application granted granted Critical
Publication of ATE130198T1 publication Critical patent/ATE130198T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT90909595T 1989-06-29 1990-06-28 Herstellung eines virus und reinigung von virenüberzugsproteinen zur impfstoffverwendung. ATE130198T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898914968A GB8914968D0 (en) 1989-06-29 1989-06-29 Production of virus and purification of viral envelope proteins for vaccine use

Publications (1)

Publication Number Publication Date
ATE130198T1 true ATE130198T1 (de) 1995-12-15

Family

ID=10659282

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90909595T ATE130198T1 (de) 1989-06-29 1990-06-28 Herstellung eines virus und reinigung von virenüberzugsproteinen zur impfstoffverwendung.

Country Status (10)

Country Link
US (2) US6455050B1 (de)
EP (1) EP0480949B2 (de)
JP (1) JP2599503B2 (de)
AT (1) ATE130198T1 (de)
CA (1) CA2056437C (de)
DE (1) DE69023648T3 (de)
DK (1) DK0480949T4 (de)
ES (1) ES2078971T5 (de)
GB (1) GB8914968D0 (de)
WO (1) WO1991000104A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223410B1 (en) 1994-08-05 2007-05-29 Sanofi Pasteur Limited Inactivated respiratory syncytial viral vaccines
ATE164313T1 (de) 1993-08-06 1998-04-15 Connaught Lab Inaktivierte respiratorische synzytial-virus- impfstoffe
US6764682B1 (en) 1994-06-16 2004-07-20 Aventis Pasteur Limited Adjuvant compositions containing more than one adjuvant
DE69534922T2 (de) * 1994-10-05 2006-11-23 Vanderbilt University, Nashville Interleukin-12 als adjuvans für paramyoxviridae impfstoffe
US6290971B1 (en) 1995-06-15 2001-09-18 Aventis Pasteur Limited Adjuvant compositions comprising a mineral salt and another immunostimulating compound
CN1285608C (zh) * 1995-09-22 2006-11-22 康诺特实验室有限公司 副流感病毒糖蛋白和疫苗
US6020182A (en) 1996-07-12 2000-02-01 Connaught Laboratories Limited Subunit respiratory syncytial virus vaccine preparation
KR101229202B1 (ko) 2002-04-26 2013-02-01 메디뮨 엘엘씨 인플루엔자 바이러스의 생산을 위한 다중 플라스미드 시스템
US7465456B2 (en) 2002-04-26 2008-12-16 Medimmune, Llc Multi plasmid system for the production of influenza virus
US20060110406A1 (en) 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
KR101251902B1 (ko) 2003-02-25 2013-04-08 메디뮨 엘엘씨 인플루엔자 백신 조성물의 제조 방법
JP4771959B2 (ja) 2003-12-23 2011-09-14 メディミューン，エルエルシー インフルエンザウイルス作製のための多重プラスミド系
US8673613B2 (en) 2007-06-18 2014-03-18 Medimmune, Llc Influenza B viruses having alterations in the hemaglutinin polypeptide
US11446374B2 (en) 2008-12-09 2022-09-20 Novavax, Inc. Modified RSV F proteins and methods of their use
MX2011006205A (es) * 2008-12-09 2011-09-01 Novavax Inc Proteinas f del vrs modificadas y metodos de uso de las mismas.
US9644187B2 (en) 2010-04-14 2017-05-09 Emd Millipore Corporation Methods of producing high titer, high purity virus stocks and methods of use thereof
CN111148509A (zh) 2017-07-24 2020-05-12 诺瓦瓦克斯股份有限公司 治疗呼吸系统疾病的方法和组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4699785A (en) * 1984-09-18 1987-10-13 The Regents Of The University Of California Cell line producing feline leukemia virus
WO1989005823A1 (en) * 1987-12-23 1989-06-29 The Upjohn Company Chimeric glycoproteins containing immunogenic segments of the glycoproteins of human respiratory syncytial virus
AU611784B2 (en) * 1988-04-22 1991-06-20 Pharmacia & Upjohn Company Chimeric glycoproteins containing immunogenic segments of human parainfluenza virus type 3

Also Published As

Publication number Publication date
ES2078971T5 (es) 2005-03-16
DE69023648T3 (de) 2005-02-03
US6306637B1 (en) 2001-10-23
DK0480949T3 (da) 1995-12-18
EP0480949B1 (de) 1995-11-15
CA2056437A1 (en) 1990-12-30
EP0480949B2 (de) 2004-08-04
CA2056437C (en) 1996-02-06
US6455050B1 (en) 2002-09-24
GB8914968D0 (en) 1989-08-23
ES2078971T3 (es) 1996-01-01
WO1991000104A1 (en) 1991-01-10
DK0480949T4 (da) 2004-12-06
DE69023648D1 (de) 1995-12-21
JPH04502410A (ja) 1992-05-07
JP2599503B2 (ja) 1997-04-09
DE69023648T2 (de) 1996-05-02
EP0480949A1 (de) 1992-04-22

Similar Documents

Publication Publication Date Title
ATE130198T1 (de) Herstellung eines virus und reinigung von virenüberzugsproteinen zur impfstoffverwendung.
FI893702A (fi) Foerfarande foer mikrobiologisk framstaellning av humant serumalbumin och andra heterologa proteiner ur jaest.
DE69727595D1 (de) Verfahren zur herstellung eines extraktes des plättchenwachstumsfaktors für zubereitungen zur wundheilung
ATE125157T1 (de) Methoden und zusammensetzungen zur impfung gegen hiv.
DE69929612D1 (de) Purifikation von viruspräparaten
HK1142093A1 (en) Process for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
BR8701528A (pt) Proteina,sequencia de dna,vetor recombinante,organismo celular,processos para producao de uma proteina e para a preparacao de um organismo unicelular,processos para a deteccao da presenca de anticorpos e de virus de aids,processos para a preparacao de uma vacina e para a preparacao de anticorpos,formulacao de vacina,anticorpos,uso,vacina,kit de teste e metodo para a prevencao de aids
DE69713112D1 (de) Zusammensetzungen und methoden zur behandlung von infektionen unter verwendung von indolicidin-analogen
IT1196484B (it) Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe
UA35639C2 (uk) Спосіб одержання композиції очищеного капсидного білка вірусу папіломи людини
DK11187A (da) Dna-sekvenser der koder for proteiner med husi-type i inhibitorers biologiske aktivitet, biotekniske fremgangsmaader til fremstilling af proteinerne o g farmaceutiske praeparater der indeholder dem
AU4149699A (en) Use of inactivated immunosuppressive and/or angiogenic immunogenic proteins, preparation method and pharmaceutical or vaccine uses
AU2567888A (en) Hiv peptides and methods for detection of hiv
ATE435034T1 (de) Expression und charakterisierung eines hiv-1 hüllproteins, das mit einer breitreaktiven neutralisierenden antikörperantwort assoziiert ist.
NO912942L (no) Vaksine for preventiv behandling av infeksjon av leverikte hos droevtyggere.
OA09653A (en) Rubella peptides
WO1992011370A3 (de) Von proteinen des hepatitis c-virus abgeleitete polypeptide und deren verwendung
AU2190288A (en) Vector for the expression of proteins of the HIV-2 virus, one of the casual agents of AIDS, cell culture infected or transformed by this vector, proteins obtained, vaccine and antibodies obtained
EP0888046A4 (de) Verfahren zur proteinproduktion mittels eines mitochondrialen translationssystems.
AU6393990A (en) Hiv related peptides
ATE4637T1 (de) Pentadecapeptid, verfahren zu seiner herstellung und immunisierendes mittel.
RU93043621A (ru) Способы получения гликопротеинов нсv, способ очистки, аналитический набор, способ выявления нсv, способ элиминации нсv, способ индукции иммунитета, гликопротеины, иммунореагенты
ES8801958A1 (es) Un procedimiento para la determinacion de virus de sida
FI883765A (fi) Antikroppar mot biologiskt aktiva polypeptider och deras anvaendning vid diagnostiska foerfaranden.

Legal Events

Date Code Title Description
EEFA Change of the company name
UEP Publication of translation of european patent specification

Ref document number: 0480949

Country of ref document: EP

EELA Cancelled due to lapse of time