IT1196484B - Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe - Google Patents

Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe

Info

Publication number
IT1196484B
IT1196484B IT21106/86A IT2110686A IT1196484B IT 1196484 B IT1196484 B IT 1196484B IT 21106/86 A IT21106/86 A IT 21106/86A IT 2110686 A IT2110686 A IT 2110686A IT 1196484 B IT1196484 B IT 1196484B
Authority
IT
Italy
Prior art keywords
useful
preparation
yeast expression
secretion vector
heterological
Prior art date
Application number
IT21106/86A
Other languages
English (en)
Other versions
IT8621106A1 (it
IT8621106A0 (it
Inventor
Cesira Galeotti
Emanuela Palla
Giovanni Raugei
Giuliano Bensi
Maria Luisa Melli
Original Assignee
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sclavo Spa filed Critical Sclavo Spa
Priority to IT21106/86A priority Critical patent/IT1196484B/it
Publication of IT8621106A0 publication Critical patent/IT8621106A0/it
Priority to EP87201264A priority patent/EP0252561A3/en
Priority to JP62171295A priority patent/JPS6387983A/ja
Priority to CA000541825A priority patent/CA1324967C/en
Publication of IT8621106A1 publication Critical patent/IT8621106A1/it
Application granted granted Critical
Publication of IT1196484B publication Critical patent/IT1196484B/it
Priority to US08/069,455 priority patent/US5432082A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT21106/86A 1986-07-11 1986-07-11 Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe IT1196484B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT21106/86A IT1196484B (it) 1986-07-11 1986-07-11 Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe
EP87201264A EP0252561A3 (en) 1986-07-11 1987-07-03 Expression and secretion vector in yeasts, useful for preparing heterologous proteins
JP62171295A JPS6387983A (ja) 1986-07-11 1987-07-10 酵母の発現及び分泌クロ−ニングベクタ−
CA000541825A CA1324967C (en) 1986-07-11 1987-07-10 Expression and secretion vector in yeasts, useful for preparing heterologous proteins
US08/069,455 US5432082A (en) 1986-07-11 1993-06-01 Expression and secretion vector in yeasts, useful for preparing heterologous proteins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21106/86A IT1196484B (it) 1986-07-11 1986-07-11 Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe

Publications (3)

Publication Number Publication Date
IT8621106A0 IT8621106A0 (it) 1986-07-11
IT8621106A1 IT8621106A1 (it) 1988-01-11
IT1196484B true IT1196484B (it) 1988-11-16

Family

ID=11176829

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21106/86A IT1196484B (it) 1986-07-11 1986-07-11 Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe

Country Status (5)

Country Link
US (1) US5432082A (it)
EP (1) EP0252561A3 (it)
JP (1) JPS6387983A (it)
CA (1) CA1324967C (it)
IT (1) IT1196484B (it)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100195632B1 (ko) * 1988-07-23 1999-06-15 스티븐 조지 가랜드 펩티드 및 dna 배열
FR2636231A1 (fr) * 1988-09-09 1990-03-16 Sanofi Sa Cellules eucaryotes recombinees productrices d'interleukine-1 (beta) mature n-glycosylee, procede et vecteurs necessaires pour leur obtention et procede d'obtention d'interleukine-1 (beta) mature n-glycosylee
IT1231156B (it) * 1989-07-19 1991-11-19 Eniricerche Spa Espressione e secrezione di interleuchina 1 beta umana matura in bacillus subtilis e mezzi e metodi per il suo ottenimento.
IT1251435B (it) * 1991-09-04 1995-05-09 Sclavo Spa Vettore genetico per la integrazione multipla stabile di sequenze di dna nel genoma dei lieviti kluyveromyces lactis e saccharomyces cerevisiae e plasmidi che lo contengono.
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
ATE197608T1 (de) * 1993-12-10 2000-12-15 Korea Inst Sci & Tech Signalsequenzen für die secretion heterologer proteine von hefe
RU2143113C1 (ru) * 1996-08-01 1999-12-20 Андрей Александрович Елов Способ диагностики инфекций путем обнаружения генетического материала возбудителя в исследуемой пробе
DE69806003T2 (de) 1997-03-12 2003-01-30 Pe Corp. (Ny), Foster City Dna polymerasen, die verbesserte fähigkeiten zum einbau markierter nukleotide besitzen
EP1009836A1 (en) * 1997-09-05 2000-06-21 Pentapharm A.G. Expression vector for improved production of polypeptides in yeast
JP2003530838A (ja) 2000-04-12 2003-10-21 ヒューマン ゲノム サイエンシズ インコーポレイテッド アルブミン融合タンパク質
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
US20050054051A1 (en) * 2001-04-12 2005-03-10 Human Genome Sciences, Inc. Albumin fusion proteins
US20050042629A1 (en) 2002-09-13 2005-02-24 Applera Corporation Thermus scotoductus nucleic acid polymerases
US7052877B2 (en) 2001-11-30 2006-05-30 Applera Corporation Thermus brockianus nucleic acid polymerases
ES2425738T3 (es) 2001-12-21 2013-10-17 Human Genome Sciences, Inc. Proteínas de fusión de la albúmina
AU2002364587A1 (en) 2001-12-21 2003-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
EP1594530A4 (en) 2003-01-22 2006-10-11 Human Genome Sciences Inc HYBRID PROTEINS OF ALBUMIN
DE10342794A1 (de) * 2003-09-16 2005-04-21 Basf Ag Sekretion von Proteinen aus Hefen
EP1848733B1 (de) 2005-02-07 2017-06-21 Basf Se Neue hydrophobinfusionsproteine, deren herstellung und verwendung
EP1866150B1 (de) 2005-03-31 2016-10-19 Basf Se Metallische substrate mit polypeptiden als haftvermittler
EA012800B1 (ru) 2005-04-01 2009-12-30 Басф Акциенгезелльшафт Применение белков в качестве деэмульгаторов
DE502006005460D1 (de) 2005-04-01 2010-01-07 Basf Se Bohrspülung enthaltend hydrophobin
DE102005027139A1 (de) 2005-06-10 2006-12-28 Basf Ag Neue Cystein-verarmte Hydrophobinfusionsproteine, deren Herstellung und Verwendung
EP1912466B1 (en) 2005-07-25 2011-09-14 Fujitsu Ltd. Sound receiver
DE102005048720A1 (de) 2005-10-12 2007-04-19 Basf Ag Verwendung von Proteinen als Antischaum-Komponente in Kraftstoffen
US7745158B2 (en) * 2005-12-14 2010-06-29 Kimberly-Clark Worldwide, Inc. Detection of secreted aspartyl proteases from Candida species
ES2374320T3 (es) 2006-08-15 2012-02-15 Basf Se Procedimiento para la producción de preparaciones de hidrofobina secas de flujo libre.
WO2008029514A1 (en) * 2006-09-07 2008-03-13 Temco Japan Co., Ltd. Vibration pickup microphone
US20140017263A1 (en) 2012-06-28 2014-01-16 Clemson University Delivery Agents for Targeted Treatment of Elastin Degradation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004330A1 (en) * 1983-04-22 1984-11-08 Amgen Secretion of exogenous polypeptides from yeast
DE3436818A1 (de) * 1984-10-06 1986-04-10 Hoechst Ag, 6230 Frankfurt Synthetische signalsequenz zum transport von proteinen in expressionssystemen

Also Published As

Publication number Publication date
IT8621106A1 (it) 1988-01-11
US5432082A (en) 1995-07-11
EP0252561A3 (en) 1989-03-29
EP0252561A2 (en) 1988-01-13
CA1324967C (en) 1993-12-07
IT8621106A0 (it) 1986-07-11
JPS6387983A (ja) 1988-04-19

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