DE3485267D1 - Herstellung von streptokokken-m-protein-immunogenen und molekularen sonden. - Google Patents

Herstellung von streptokokken-m-protein-immunogenen und molekularen sonden.

Info

Publication number
DE3485267D1
DE3485267D1 DE8484903223T DE3485267T DE3485267D1 DE 3485267 D1 DE3485267 D1 DE 3485267D1 DE 8484903223 T DE8484903223 T DE 8484903223T DE 3485267 T DE3485267 T DE 3485267T DE 3485267 D1 DE3485267 D1 DE 3485267D1
Authority
DE
Germany
Prior art keywords
streptococcle
preparation
molecular probe
protein immunogenic
immunogenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484903223T
Other languages
English (en)
Inventor
R Scott
A Fischetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
Emory University
Original Assignee
Rockefeller University
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rockefeller University, Emory University filed Critical Rockefeller University
Application granted granted Critical
Publication of DE3485267D1 publication Critical patent/DE3485267D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
DE8484903223T 1983-08-10 1984-08-09 Herstellung von streptokokken-m-protein-immunogenen und molekularen sonden. Expired - Lifetime DE3485267D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52196283A 1983-08-10 1983-08-10
US06/621,716 US4784948A (en) 1983-08-10 1984-06-18 Production of streptococcal m protein immunogens and molecular probes
PCT/US1984/001261 WO1985000832A1 (en) 1983-08-10 1984-08-09 Production of streptococal m protein immunogens and molecular probes

Publications (1)

Publication Number Publication Date
DE3485267D1 true DE3485267D1 (de) 1991-12-19

Family

ID=27060649

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484903223T Expired - Lifetime DE3485267D1 (de) 1983-08-10 1984-08-09 Herstellung von streptokokken-m-protein-immunogenen und molekularen sonden.

Country Status (8)

Country Link
US (2) US4784948A (de)
EP (1) EP0152468B1 (de)
JP (2) JP2926180B2 (de)
AU (1) AU574385B2 (de)
CA (1) CA1339266C (de)
DE (1) DE3485267D1 (de)
DK (1) DK158585A (de)
WO (1) WO1985000832A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3678702D1 (de) * 1985-12-28 1991-05-16 Ohgen Research Lab Ltd Antitumorprotein-gen von streptococcus pyogenes su, plasmide, die das gen enthalten, transformantenzellen, die die plasmide beherbergen, und verfahren zur herstellung des antitumorproteins.
JP2837846B2 (ja) * 1986-10-08 1998-12-16 バーンスタイン，デビッド グループａ連鎖球菌抗原を露出させる方法およびグループａ連鎖球菌を同定するための改善された診断試験
ATE78513T1 (de) * 1987-05-13 1992-08-15 Hightech Receptor Ab Immunoglobulin-a-rezeptor-protein (arp), sowie dessen klonierung und expression.
US5162226A (en) * 1987-08-24 1992-11-10 University Of Tennessee Research Corp. (U.T.R.C.) Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products
US5124153A (en) * 1987-08-24 1992-06-23 University Of Tennessee Research Corp. Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products
US6602507B1 (en) * 1988-03-25 2003-08-05 The Rockefeller University Synthetic peptides from streptococcal M protein and vaccines prepared therefrom
WO1990015872A1 (en) * 1989-06-21 1990-12-27 The Rockefeller University Recombinant poxvirus and streptococcal m protein vaccine
US5616686A (en) * 1990-05-11 1997-04-01 The Rockefeller University Polypeptide of a hybrid surface protein by bacteria
US5476929A (en) * 1991-02-15 1995-12-19 Uab Research Foundation Structural gene of pneumococcal protein
NL9100510A (nl) * 1991-03-21 1992-10-16 Centraal Diergeneeskundig Inst Dna-sequenties die coderen voor kenmerken van virulentie van streptococcus suis en delen daarvan, daarvan afgeleide polypeptiden en antilichamen, alsmede toepassing daarvan bij de diagnose van en de bescherming tegen infectie met s. suis bij zoogdieren, waaronder de mens.
US5232831A (en) * 1991-06-28 1993-08-03 Gen-Probe Incorporated Nucleic acid probes to streptococcus pyogenes
AU5128593A (en) * 1992-09-16 1994-04-12 University Of Tennessee Research Corporation, The Antigen of hybrid m protein and carrier for group a streptococcal vaccine
WO1994006421A1 (en) * 1992-09-16 1994-03-31 The University Of Tennessee Research Corporation Recombinant multivalent m protein vaccine
WO1994007469A1 (en) * 1992-09-25 1994-04-14 Dynagen, Inc. An immunobooster for delayed release of immunogen
ATE291625T1 (de) 1995-06-07 2005-04-15 Univ Minnesota Streptococcus toxinmutanten und verfahren zu deren anwendung
DE19535321A1 (de) * 1995-09-22 1997-03-27 Max Planck Gesellschaft Neues Adhäsin aus Helicobacter pylori
US20020136739A1 (en) * 1996-07-12 2002-09-26 Cates George A. Subunit respiratory syncytial virus preparation
US5882896A (en) 1996-09-24 1999-03-16 Smithkline Beecham Corporation M protein
US6774218B2 (en) 1996-12-06 2004-08-10 Regents Of The University Of Minnesota Mutants of streptococcal toxin C and methods of use
CA2273824C (en) 1996-12-06 2007-05-08 The Regents Of The University Of Minnesota Mutants of streptococcal toxin c and methods of use
CA2273822A1 (en) 1996-12-06 1998-06-11 The Regents Of The University Of Minnesota Mutants of streptococcal toxin a and methods of use
US6716433B1 (en) * 1997-09-12 2004-04-06 University Of Tennessee Research Foundation Group a streptococcal vaccines
US20030129146A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti The use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6752988B1 (en) 2000-04-28 2004-06-22 New Horizons Diagnostic Corp Method of treating upper resiratory illnesses
US6056954A (en) 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US20030082110A1 (en) * 1997-10-31 2003-05-01 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6277399B1 (en) 1997-10-31 2001-08-21 New Horizon Diagnostics Corporation Composition incorporating bacterial phage associated lysing enzymes for treating dermatological infections
US6428784B1 (en) * 1997-10-31 2002-08-06 New Horizons Diagnostics Corp Vaginal suppository for treating group B Streptococcus infection
US20030129147A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US5997862A (en) * 1997-10-31 1999-12-07 New Horizons Diagnostics Corporation Therapeutic treatment of group A streptococcal infections
US6423299B1 (en) 1997-10-31 2002-07-23 Vincent Fischetti Composition for treatment of a bacterial infection of an upper respiratory tract
US6406692B1 (en) * 1997-10-31 2002-06-18 New Horizons Diagnostics Corp Composition for treatment of an ocular bacterial infection
US6432444B1 (en) 1997-10-31 2002-08-13 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymes for treating dermatological infections
US7232576B2 (en) 1997-10-31 2007-06-19 New Horizons Diagnostics Corp Throat lozenge for the treatment of Streptococcus Group A
US20020136712A1 (en) * 1997-10-31 2002-09-26 Fischetti Vincent Bacterial phage associated lysing enzymes for the prophylactic and therapeutic treatment of colonization and infections caused by streptococcus pneumoniae
GB9807890D0 (en) * 1998-04-09 1998-06-10 Actinova Ltd Peptides
US20020127215A1 (en) * 1999-09-14 2002-09-12 Lawrence Loomis Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections
US7063837B2 (en) * 1999-09-14 2006-06-20 New Horizons Diagnostics Corp Syrup composition containing phage associated lytic enzymes
US20070128229A1 (en) * 2002-04-12 2007-06-07 Wyeth Surface proteins of Streptococcus pyogenes
JP2004533236A (ja) * 2001-04-13 2004-11-04 ワイエス 化膿性連鎖球菌（Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｙｏｇｅｎｅｓ）の表面タンパク質
US20040213765A1 (en) * 2001-07-13 2004-10-28 Vincent Fischetti Use of bacterial phage associated lytic enzymes to prevent food poisoning
WO2003060143A2 (en) * 2001-10-26 2003-07-24 Id Biomedical Corporation Of Washington Efficient protein expression system
EP2356135B1 (de) 2008-11-05 2017-10-25 Wyeth LLC Immunogene multikomponentenzusammensetzung zur prävention einer erkrankung mit beta-hämolytischen streptokokken (bhs)
US20210102876A1 (en) * 2017-03-02 2021-04-08 Hero Scientific Ltd. Testing for particulates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284537A (en) * 1980-07-03 1981-08-18 The United States Of America As Represented By The Department Of Health And Human Services Conjugate of streptococcal M protein peptide vaccine
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
US4466917A (en) * 1981-02-12 1984-08-21 New York University Malaria vaccine
CA1338705C (en) * 1981-10-22 1996-11-12 Roy Curtiss Iii Vaccines obtained from antigenic gene products of recombinant genes

Also Published As

Publication number Publication date
DK158585D0 (da) 1985-04-09
EP0152468B1 (de) 1991-11-13
US5840314A (en) 1998-11-24
JP2614176B2 (ja) 1997-05-28
JPH06233693A (ja) 1994-08-23
EP0152468A4 (de) 1987-03-12
AU574385B2 (en) 1988-07-07
JPS60501689A (ja) 1985-10-11
WO1985000832A1 (en) 1985-02-28
DK158585A (da) 1985-04-09
US4784948A (en) 1988-11-15
AU3316184A (en) 1985-03-12
JP2926180B2 (ja) 1999-07-28
EP0152468A1 (de) 1985-08-28
CA1339266C (en) 1997-08-12

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