ES2078971T3 - Produccion de virus y purificacion de proteinas con envoltura virica para uso en vacunas. - Google Patents

Produccion de virus y purificacion de proteinas con envoltura virica para uso en vacunas.

Info

Publication number
ES2078971T3
ES2078971T3 ES90909595T ES90909595T ES2078971T3 ES 2078971 T3 ES2078971 T3 ES 2078971T3 ES 90909595 T ES90909595 T ES 90909595T ES 90909595 T ES90909595 T ES 90909595T ES 2078971 T3 ES2078971 T3 ES 2078971T3
Authority
ES
Spain
Prior art keywords
viric
vaccines
protein purification
envelope protein
virus production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909595T
Other languages
English (en)
Other versions
ES2078971T5 (es
Inventor
Mary Elizabeth Ewasyshyn
Barry Ian Caplan
Anne-Marie Bonneau
Michel Henri Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
Original Assignee
Connaught Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10659282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2078971(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Connaught Laboratories Ltd filed Critical Connaught Laboratories Ltd
Publication of ES2078971T3 publication Critical patent/ES2078971T3/es
Application granted granted Critical
Publication of ES2078971T5 publication Critical patent/ES2078971T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PRODUCEN GLICOPROTEINAS DE ENVOLVIMIENTO INMUNOGENICO DE VIRUS ENVUELTOS, TALES COMO DE LA FAMILIA PARAMIXOVIRIDAE, PARTICULARMENTE PIV-3 Y RSV, AL CULTIVAR EL VIRUS CON LA AUSENCIA SUSTANCIAL DE PROTEINAS DE SUERO EXOGENO, AISLANDO EL VIRUS DEL CULTIVO DE TEJIDO, SOLUBILIZANDO LA ENVOLTURA DE GLICOPROTEINAS Y AISLANDO LAS GLICOPROTEINAS SOLUBILIZADAS ENVUELTAS POR CROMATOGRAFIA.
ES90909595T 1989-06-29 1990-06-28 Produccion de vacuna virica. Expired - Lifetime ES2078971T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8914968 1989-06-29
GB898914968A GB8914968D0 (en) 1989-06-29 1989-06-29 Production of virus and purification of viral envelope proteins for vaccine use

Publications (2)

Publication Number Publication Date
ES2078971T3 true ES2078971T3 (es) 1996-01-01
ES2078971T5 ES2078971T5 (es) 2005-03-16

Family

ID=10659282

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90909595T Expired - Lifetime ES2078971T5 (es) 1989-06-29 1990-06-28 Produccion de vacuna virica.

Country Status (10)

Country Link
US (2) US6455050B1 (es)
EP (1) EP0480949B2 (es)
JP (1) JP2599503B2 (es)
AT (1) ATE130198T1 (es)
CA (1) CA2056437C (es)
DE (1) DE69023648T3 (es)
DK (1) DK0480949T4 (es)
ES (1) ES2078971T5 (es)
GB (1) GB8914968D0 (es)
WO (1) WO1991000104A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223410B1 (en) 1994-08-05 2007-05-29 Sanofi Pasteur Limited Inactivated respiratory syncytial viral vaccines
WO1995004545A1 (en) 1993-08-06 1995-02-16 Connaught Laboratories Limited Inactivated respiratory syncytial viral vaccines
US6764682B1 (en) 1994-06-16 2004-07-20 Aventis Pasteur Limited Adjuvant compositions containing more than one adjuvant
DK0784486T3 (da) * 1994-10-05 2006-08-14 Univ Vanderbilt Interleukin-12 som en adjuvans til Paramyxoviridae-vacciner
US6290971B1 (en) 1995-06-15 2001-09-18 Aventis Pasteur Limited Adjuvant compositions comprising a mineral salt and another immunostimulating compound
AU712213B2 (en) * 1995-09-22 1999-11-04 Connaught Laboratories Limited Parainfluenza virus glycoproteins and vaccines
US6020182A (en) * 1996-07-12 2000-02-01 Connaught Laboratories Limited Subunit respiratory syncytial virus vaccine preparation
US7465456B2 (en) 2002-04-26 2008-12-16 Medimmune, Llc Multi plasmid system for the production of influenza virus
AU2003231083A1 (en) 2002-04-26 2003-11-10 Medimmune, Llc Multi plasmid system for the production of influenza virus
US20060110406A1 (en) 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
EP1597400B8 (en) 2003-02-25 2013-10-09 MedImmune, LLC Methods of producing influenza vaccine compositions
DE602004027537D1 (es) 2003-12-23 2010-07-15 Medimmune Inc
EP2674486A1 (en) 2007-06-18 2013-12-18 MedImmune, LLC Influenza B viruses having alterations in the hemaglutinin polypeptide
DK3067064T3 (da) * 2008-12-09 2020-06-08 Novavax Inc Modificerede rsv-f-proteiner og fremgangsmåder til anvendelse deraf
US11446374B2 (en) 2008-12-09 2022-09-20 Novavax, Inc. Modified RSV F proteins and methods of their use
SG184833A1 (en) 2010-04-14 2012-11-29 Emd Millipore Corp Methods of producing high titer, high purity virus stocks and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4699785A (en) * 1984-09-18 1987-10-13 The Regents Of The University Of California Cell line producing feline leukemia virus
AU617739B2 (en) * 1987-12-23 1991-12-05 Pharmacia & Upjohn Company Chimeric glycoproteins containing immunogenic segments of the glycoproteins of human respiratory syncytial virus
ATE105334T1 (de) * 1988-04-22 1994-05-15 Upjohn Co Schimaerische glykoproteine enthaltende immunogenische abschnitte von menschlichem parainfluenzavirus typ 3.

Also Published As

Publication number Publication date
GB8914968D0 (en) 1989-08-23
EP0480949A1 (en) 1992-04-22
EP0480949B1 (en) 1995-11-15
DK0480949T3 (da) 1995-12-18
DE69023648D1 (de) 1995-12-21
EP0480949B2 (en) 2004-08-04
ES2078971T5 (es) 2005-03-16
DK0480949T4 (da) 2004-12-06
DE69023648T2 (de) 1996-05-02
ATE130198T1 (de) 1995-12-15
CA2056437C (en) 1996-02-06
US6455050B1 (en) 2002-09-24
US6306637B1 (en) 2001-10-23
JP2599503B2 (ja) 1997-04-09
CA2056437A1 (en) 1990-12-30
DE69023648T3 (de) 2005-02-03
JPH04502410A (ja) 1992-05-07
WO1991000104A1 (en) 1991-01-10

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