DE69023648D1 - Herstellung eines virus und reinigung von virenüberzugsproteinen zur impfstoffverwendung. - Google Patents

Herstellung eines virus und reinigung von virenüberzugsproteinen zur impfstoffverwendung.

Info

Publication number
DE69023648D1
DE69023648D1 DE69023648T DE69023648T DE69023648D1 DE 69023648 D1 DE69023648 D1 DE 69023648D1 DE 69023648 T DE69023648 T DE 69023648T DE 69023648 T DE69023648 T DE 69023648T DE 69023648 D1 DE69023648 D1 DE 69023648D1
Authority
DE
Germany
Prior art keywords
virus
cleaning
production
vaccine use
coating proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69023648T
Other languages
English (en)
Other versions
DE69023648T3 (de
DE69023648T2 (de
Inventor
Mary Elizabeth Ewasyshyn
Barry Ian Caplan
Anne-Marie Bonneau
Michel Henri Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
Original Assignee
Connaught Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10659282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69023648(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Connaught Laboratories Ltd filed Critical Connaught Laboratories Ltd
Publication of DE69023648D1 publication Critical patent/DE69023648D1/de
Application granted granted Critical
Publication of DE69023648T2 publication Critical patent/DE69023648T2/de
Publication of DE69023648T3 publication Critical patent/DE69023648T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DE69023648T 1989-06-29 1990-06-28 Herstellung eines virusimpfstoffes Expired - Lifetime DE69023648T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8914968 1989-06-29
GB898914968A GB8914968D0 (en) 1989-06-29 1989-06-29 Production of virus and purification of viral envelope proteins for vaccine use
PCT/CA1990/000205 WO1991000104A1 (en) 1989-06-29 1990-06-28 Production of virus and purification of viral envelope proteins for vaccine use

Publications (3)

Publication Number Publication Date
DE69023648D1 true DE69023648D1 (de) 1995-12-21
DE69023648T2 DE69023648T2 (de) 1996-05-02
DE69023648T3 DE69023648T3 (de) 2005-02-03

Family

ID=10659282

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69023648T Expired - Lifetime DE69023648T3 (de) 1989-06-29 1990-06-28 Herstellung eines virusimpfstoffes

Country Status (10)

Country Link
US (2) US6455050B1 (de)
EP (1) EP0480949B2 (de)
JP (1) JP2599503B2 (de)
AT (1) ATE130198T1 (de)
CA (1) CA2056437C (de)
DE (1) DE69023648T3 (de)
DK (1) DK0480949T4 (de)
ES (1) ES2078971T5 (de)
GB (1) GB8914968D0 (de)
WO (1) WO1991000104A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223410B1 (en) 1994-08-05 2007-05-29 Sanofi Pasteur Limited Inactivated respiratory syncytial viral vaccines
CN1103603C (zh) 1993-08-06 2003-03-26 康诺特实验室有限公司 灭活的呼吸合胞体病毒疫苗
US6764682B1 (en) * 1994-06-16 2004-07-20 Aventis Pasteur Limited Adjuvant compositions containing more than one adjuvant
EP0784486B1 (de) * 1994-10-05 2006-04-05 Vanderbilt University Interleukin-12 als adjuvans für paramyoxviridae impfstoffe
US6290971B1 (en) 1995-06-15 2001-09-18 Aventis Pasteur Limited Adjuvant compositions comprising a mineral salt and another immunostimulating compound
BR9610590A (pt) * 1995-09-22 2000-10-24 Connaught Lab Glicoproteìnas e vacinas de vìrus parainfluenza
US6020182A (en) * 1996-07-12 2000-02-01 Connaught Laboratories Limited Subunit respiratory syncytial virus vaccine preparation
US7465456B2 (en) 2002-04-26 2008-12-16 Medimmune, Llc Multi plasmid system for the production of influenza virus
CN1678345A (zh) 2002-04-26 2005-10-05 米迪缪尼疫苗股份有限公司 制备流感病毒的多质粒系统
EP2481819A1 (de) 2003-02-25 2012-08-01 MedImmune Vaccines, Inc. Querstromfiltration in der Herstellung von stabilisierten Influenza-Impfstoff-Zusammensetzungen
US20060110406A1 (en) 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
CA2551489C (en) 2003-12-23 2013-09-03 Gregory Duke Multi plasmid system for the production of influenza virus
WO2008157583A1 (en) 2007-06-18 2008-12-24 Medimmune, Llc Influenza b viruses having alterations in the hemaglutinin polypeptide
US11446374B2 (en) 2008-12-09 2022-09-20 Novavax, Inc. Modified RSV F proteins and methods of their use
HUE051666T2 (hu) 2008-12-09 2021-03-29 Novavax Inc Módosított RSV F fehérjék és alkalmazásuk módszerei
JP2013523175A (ja) 2010-04-14 2013-06-17 イーエムディー・ミリポア・コーポレーション 高力価、高純度のウイルスストックの作製方法及びその使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4699785A (en) * 1984-09-18 1987-10-13 The Regents Of The University Of California Cell line producing feline leukemia virus
ATE85622T1 (de) * 1987-12-23 1993-02-15 Upjohn Co Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus.
WO1989010405A1 (en) * 1988-04-22 1989-11-02 The Upjohn Company Chimeric glycoproteins containig immunogenic segments of human parainfluenza virus type 3

Also Published As

Publication number Publication date
GB8914968D0 (en) 1989-08-23
JP2599503B2 (ja) 1997-04-09
EP0480949B2 (de) 2004-08-04
DK0480949T4 (da) 2004-12-06
ES2078971T3 (es) 1996-01-01
ATE130198T1 (de) 1995-12-15
JPH04502410A (ja) 1992-05-07
DK0480949T3 (da) 1995-12-18
US6455050B1 (en) 2002-09-24
EP0480949A1 (de) 1992-04-22
WO1991000104A1 (en) 1991-01-10
DE69023648T3 (de) 2005-02-03
ES2078971T5 (es) 2005-03-16
CA2056437A1 (en) 1990-12-30
US6306637B1 (en) 2001-10-23
EP0480949B1 (de) 1995-11-15
CA2056437C (en) 1996-02-06
DE69023648T2 (de) 1996-05-02

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PASTEUR LTD., TORONTO, ONTARIO, CA