ATE2090T1 - Verfahren zur herstellung eines plasminogenaktivators, so erhaltener aktivator und ihn enthaltendes arzneimittel. - Google Patents
Verfahren zur herstellung eines plasminogenaktivators, so erhaltener aktivator und ihn enthaltendes arzneimittel.Info
- Publication number
- ATE2090T1 ATE2090T1 AT80401111T AT80401111T ATE2090T1 AT E2090 T1 ATE2090 T1 AT E2090T1 AT 80401111 T AT80401111 T AT 80401111T AT 80401111 T AT80401111 T AT 80401111T AT E2090 T1 ATE2090 T1 AT E2090T1
- Authority
- AT
- Austria
- Prior art keywords
- activator
- plasminogen activator
- manufacture
- plasminogen
- fibrin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7919432A FR2462165A2 (fr) | 1973-12-03 | 1979-07-27 | Procede perfectionne de preparation d'activateur du plasminogene |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE2090T1 true ATE2090T1 (de) | 1983-01-15 |
Family
ID=9228380
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT80401111T ATE2090T1 (de) | 1979-07-27 | 1980-07-25 | Verfahren zur herstellung eines plasminogenaktivators, so erhaltener aktivator und ihn enthaltendes arzneimittel. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4314994A (de) |
EP (1) | EP0023860B1 (de) |
JP (1) | JPS5620596A (de) |
AT (1) | ATE2090T1 (de) |
CA (1) | CA1154671A (de) |
DE (1) | DE3061429D1 (de) |
ES (1) | ES494343A0 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2121050B (en) * | 1979-07-05 | 1986-03-26 | Genentech Inc | Preparation of functional human urokinase proteins |
FR2483234A2 (fr) * | 1980-05-29 | 1981-12-04 | Fabre Sa Pierre | Composition ophtalmique contenant un activateur du plasminogene |
FI831484L (fi) * | 1982-05-05 | 1983-11-06 | Genentech Inc | Plasminogen aktivator foer maenskovaevnad |
US5185259A (en) * | 1982-05-05 | 1993-02-09 | Genentech, Inc. | Truncated human tissue plasminogen activator |
US4853330A (en) * | 1983-04-07 | 1989-08-01 | Genentech, Inc. | Human tissue plasminogen activator |
DE3348289C2 (de) * | 1982-05-05 | 1994-05-05 | Genentech Inc | Verfahren zur Herstellung von Human-Gewebe-Plasminogen-Aktivator |
AR241654A1 (es) * | 1982-05-05 | 1992-10-30 | Genentech Inc | Procedimiento para producir activador de plasminogeno de tejido humano. |
US4766075A (en) * | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
MX197183A (es) * | 1982-05-05 | 1994-02-28 | Genentech Inc | Activador de plasminogeno de tejido humano |
DE3382389D1 (de) * | 1982-12-14 | 1991-10-02 | South African Inventions | Plasminogenaktivator. |
US4753879A (en) * | 1984-08-27 | 1988-06-28 | Biogen N.V. | Modified tissue plasminogen activators |
DE3512910A1 (de) * | 1985-04-11 | 1986-10-16 | Behringwerke Ag, 3550 Marburg | Verfahren zur reinigung von plasminogenaktivatoren |
FI85334C (fi) * | 1985-05-28 | 1992-04-10 | Wellcome Found | Foerfarande foer framstaellning av en vattenbaserad, vaevnadsplasminogenaktivator (t-pa) innehaollande, koncentrerad parenterad loesning. |
US4929560A (en) * | 1988-02-03 | 1990-05-29 | Damon Biotech, Inc. | Recovery of tissue plasminogen activator |
US6207151B1 (en) * | 1989-09-21 | 2001-03-27 | Mitsui Chemicals Inc. | Aqueous solution of t-PA |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3998947A (en) * | 1973-11-30 | 1976-12-21 | Pierre Fabre S.A. | Process for obtaining a plasminogen activator |
FR2252842B1 (de) * | 1973-12-03 | 1977-11-04 | Fabre Sa Pierre | |
FR2347048A2 (fr) * | 1976-04-07 | 1977-11-04 | Choay Sa | Compositions constituees par des composes du type plasminogene, notamment d'origine placentaire, procede d'obtention des ces compositions, et medicaments contenant ces compositions |
FR2310133A2 (fr) * | 1975-05-05 | 1976-12-03 | Fabre Sa Pierre | Nouveau medicament comportant un activateur du plasminogene perfectionne |
-
1980
- 1980-07-24 ES ES1980494343A patent/ES494343A0/es active Granted
- 1980-07-24 US US06/172,029 patent/US4314994A/en not_active Expired - Lifetime
- 1980-07-24 CA CA000357117A patent/CA1154671A/fr not_active Expired
- 1980-07-25 EP EP80401111A patent/EP0023860B1/de not_active Expired
- 1980-07-25 DE DE8080401111T patent/DE3061429D1/de not_active Expired
- 1980-07-25 AT AT80401111T patent/ATE2090T1/de not_active IP Right Cessation
- 1980-07-28 JP JP10352680A patent/JPS5620596A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US4314994A (en) | 1982-02-09 |
DE3061429D1 (en) | 1983-01-27 |
EP0023860A2 (de) | 1981-02-11 |
JPS5620596A (en) | 1981-02-26 |
ES8106836A2 (es) | 1981-10-01 |
EP0023860B1 (de) | 1982-12-22 |
EP0023860A3 (en) | 1981-02-18 |
CA1154671A (fr) | 1983-10-04 |
ES494343A0 (es) | 1981-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |