GB1501436A - Aralkylamine derivatives - Google Patents
Aralkylamine derivativesInfo
- Publication number
- GB1501436A GB1501436A GB17328/75A GB1732875A GB1501436A GB 1501436 A GB1501436 A GB 1501436A GB 17328/75 A GB17328/75 A GB 17328/75A GB 1732875 A GB1732875 A GB 1732875A GB 1501436 A GB1501436 A GB 1501436A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- formula
- compound
- hydrogenation
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003974 aralkylamines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 11
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 238000005984 hydrogenation reaction Methods 0.000 abstract 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- -1 methoxy, ethoxy, methylthio Chemical group 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 101100240517 Caenorhabditis elegans nhr-11 gene Proteins 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000005904 alkaline hydrolysis reaction Methods 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 125000004705 ethylthio group Chemical group C(C)S* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 230000001975 sympathomimetic effect Effects 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2420618A DE2420618C2 (de) | 1974-04-27 | 1974-04-27 | Aminoalkylanilide, Verfahren zu ihrer Herstellung sowie pharmazeutische Zubereitungen, die diese Aminoalkylanilide enthalten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1501436A true GB1501436A (en) | 1978-02-15 |
Family
ID=5914207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB17328/75A Expired GB1501436A (en) | 1974-04-27 | 1975-04-25 | Aralkylamine derivatives |
Country Status (27)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0180994A3 (en) * | 1984-11-08 | 1987-09-23 | Syntex (U.S.A.) Inc. | Antihypertensive dialkyl aminoethylaniline derivatives |
| US6329399B1 (en) * | 1997-08-05 | 2001-12-11 | Pola Chemical Industries, Inc. | Antifungal amine derivatives and processing for producing the same |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4163060A (en) * | 1974-04-08 | 1979-07-31 | U.S. Philips Corporation | Aralkylamino carboxylic acids and derivatives having spasmolytic activity |
| US4146645A (en) * | 1974-04-27 | 1979-03-27 | Boehringer Ingelheim Gmbh | Hypertensive phenylalkylamines and salts thereof |
| US4145363A (en) * | 1975-02-05 | 1979-03-20 | Yamanouchi Pharmaceutical Co., Ltd. | 4-Carbamoylamino-α-aminomethylbenzyl alcohol derivatives |
| US4088785A (en) * | 1976-03-25 | 1978-05-09 | William H. Rorer, Inc. | Amidinoureas for the treatment of cardinascular disorders |
| US4754047A (en) * | 1979-08-16 | 1988-06-28 | American Cyanamid Company | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and/or improving the efficiency of feed utilization thereby |
| US4477470A (en) * | 1983-10-20 | 1984-10-16 | Smithkline Beckman Corporation | Method for producing diuresis using m-amino-α-methylphenethylamine |
| JPS6155683U (enrdf_load_stackoverflow) * | 1984-09-17 | 1986-04-14 | ||
| JPS61130876U (enrdf_load_stackoverflow) * | 1984-09-18 | 1986-08-15 | ||
| US4752621A (en) * | 1985-04-11 | 1988-06-21 | Syntex (U.S.A.) Inc. | Arylalkyl amines useful for lowering intraocular pressure |
| US4798687A (en) * | 1987-02-06 | 1989-01-17 | Pennwalt Corporation | 2-Amino-N-[1,2-Diphenyl-1-(thifluoromethyl)ethyl]acetamide derivatives |
| JPH01116183U (enrdf_load_stackoverflow) * | 1988-01-29 | 1989-08-04 | ||
| JPH01116184U (enrdf_load_stackoverflow) * | 1988-01-29 | 1989-08-04 | ||
| US5741818A (en) | 1995-06-07 | 1998-04-21 | University Of Saskatchewan | Semicarbazones having CNS activity and pharmaceutical preparations containing same |
| KR20010020201A (ko) | 1997-04-22 | 2001-03-15 | 코센시스 인크 | 탄소고리 및 헤테로고리 치환된 세미카르바존 및 티오세미카르바존과 그들의 사용 방법 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL123536C (enrdf_load_stackoverflow) * | 1963-07-09 |
-
1974
- 1974-04-27 DE DE2420618A patent/DE2420618C2/de not_active Expired
-
1975
- 1975-04-02 AT AT247875A patent/AT350529B/de not_active IP Right Cessation
- 1975-04-22 FI FI751199A patent/FI63931C/fi not_active IP Right Cessation
- 1975-04-24 YU YU01052/75A patent/YU105275A/xx unknown
- 1975-04-24 DK DK180675A patent/DK180675A/da not_active Application Discontinuation
- 1975-04-25 IL IL47170A patent/IL47170A/xx unknown
- 1975-04-25 BE BE155812A patent/BE828430A/xx not_active IP Right Cessation
- 1975-04-25 CS CS752917A patent/CS216827B2/cs unknown
- 1975-04-25 SE SE7504858A patent/SE411205B/xx unknown
- 1975-04-25 JP JP50050607A patent/JPS5828269B2/ja not_active Expired
- 1975-04-25 CS CS756837A patent/CS216828B2/cs unknown
- 1975-04-25 SU SU2128340A patent/SU555843A3/ru active
- 1975-04-25 HU HU75BO00001554A patent/HU172615B/hu unknown
- 1975-04-25 IE IE936/75A patent/IE42119B1/en unknown
- 1975-04-25 US US05/571,719 patent/US4015011A/en not_active Expired - Lifetime
- 1975-04-25 CH CH530375A patent/CH614697A5/xx not_active IP Right Cessation
- 1975-04-25 DD DD185702A patent/DD122374A5/xx unknown
- 1975-04-25 BG BG030690A patent/BG26372A4/xx unknown
- 1975-04-25 PL PL1975193923A patent/PL96308B1/pl unknown
- 1975-04-25 GB GB17328/75A patent/GB1501436A/en not_active Expired
- 1975-04-25 PL PL1975179934A patent/PL96224B1/pl unknown
- 1975-04-25 CA CA225,445A patent/CA1061357A/en not_active Expired
- 1975-04-25 NL NL7504917A patent/NL7504917A/xx not_active Application Discontinuation
- 1975-04-25 ZA ZA00752685A patent/ZA752685B/xx unknown
- 1975-04-25 FR FR7513097A patent/FR2268520B1/fr not_active Expired
- 1975-04-25 NO NO751491A patent/NO141207C/no unknown
- 1975-04-25 RO RO7582093A patent/RO70894A/ro unknown
- 1975-04-25 BG BG029781A patent/BG27738A3/xx unknown
- 1975-04-25 RO RO7586026A patent/RO81766A/ro unknown
- 1975-04-26 ES ES437032A patent/ES437032A1/es not_active Expired
- 1975-04-28 PH PH17108A patent/PH11982A/en unknown
-
1976
- 1976-06-10 SU SU762370950A patent/SU606549A3/ru active
- 1976-10-19 ES ES452510A patent/ES452510A1/es not_active Expired
- 1976-10-19 ES ES452514A patent/ES452514A1/es not_active Expired
- 1976-10-19 ES ES452512A patent/ES452512A1/es not_active Expired
- 1976-10-19 ES ES452513A patent/ES452513A1/es not_active Expired
- 1976-10-19 ES ES452515A patent/ES452515A1/es not_active Expired
- 1976-10-19 ES ES452511A patent/ES452511A1/es not_active Expired
-
1977
- 1977-11-24 PH PH20480A patent/PH14732A/en unknown
-
1978
- 1978-09-26 SE SE7810002A patent/SE7810002L/xx unknown
-
1979
- 1979-02-22 CH CH176579A patent/CH616401A5/de not_active IP Right Cessation
- 1979-02-22 CH CH176679A patent/CH616146A5/de not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0180994A3 (en) * | 1984-11-08 | 1987-09-23 | Syntex (U.S.A.) Inc. | Antihypertensive dialkyl aminoethylaniline derivatives |
| US6329399B1 (en) * | 1997-08-05 | 2001-12-11 | Pola Chemical Industries, Inc. | Antifungal amine derivatives and processing for producing the same |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |