GB1123565A - New substituted benzylamines and their salts and process for preparation - Google Patents
New substituted benzylamines and their salts and process for preparationInfo
- Publication number
- GB1123565A GB1123565A GB49706/65A GB4970665A GB1123565A GB 1123565 A GB1123565 A GB 1123565A GB 49706/65 A GB49706/65 A GB 49706/65A GB 4970665 A GB4970665 A GB 4970665A GB 1123565 A GB1123565 A GB 1123565A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- hydrogen
- methyl
- salts
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Novel compounds of the general formula <FORM:1123565/C2/1> and acid addition salts thereof, in which X represents a halogen atom, or a methyl, trifluoromethyl or methoxy radical and R represents a hydrogen atom or a methyl radical, are prepared, either by N-methylation of the compound of the above formula wherein R is hydrogen by means of a methyl halide or a mixture of formic acid and formaldehyde, or where R is hydrogen by reduction of a compound of the general formula <FORM:1123565/C2/2> N-benzylidene-2-amino-1-phenyl propanes of the last general formula above are prepared by reacting the suitably substituted benzaldehyde with D-, L- or DL-amphetamine. Pharmaceutical compositions having anorexigenic activity comprise compounds of the first general formula above and an inert carrier and are in conventional form for oral or parenteral administration.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR995887A FR1429306A (en) | 1964-11-23 | 1964-11-23 | Novel substituted benzylamines and their salts, and method of preparation |
| FR6300A FR4066M (en) | 1964-11-23 | 1965-02-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1123565A true GB1123565A (en) | 1968-08-14 |
Family
ID=26162171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB49706/65A Expired GB1123565A (en) | 1964-11-23 | 1965-11-23 | New substituted benzylamines and their salts and process for preparation |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE672721A (en) |
| DE (1) | DE1518334C3 (en) |
| FR (2) | FR1429306A (en) |
| GB (1) | GB1123565A (en) |
| NL (1) | NL139961B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004022532A1 (en) * | 2002-09-09 | 2004-03-18 | Richter Gedeon Vegyészeti Gyár Rt. | Benzenesulphonamides and process for their preparation |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10116816A1 (en) * | 2001-04-04 | 2002-10-17 | Basf Ag | Process for the preparation of N-benzylamines |
-
1964
- 1964-11-23 FR FR995887A patent/FR1429306A/en not_active Expired
-
1965
- 1965-02-19 FR FR6300A patent/FR4066M/fr not_active Expired
- 1965-11-15 DE DE19651518334 patent/DE1518334C3/en not_active Expired
- 1965-11-23 BE BE672721D patent/BE672721A/xx unknown
- 1965-11-23 GB GB49706/65A patent/GB1123565A/en not_active Expired
- 1965-11-23 NL NL6515158A patent/NL139961B/en not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004022532A1 (en) * | 2002-09-09 | 2004-03-18 | Richter Gedeon Vegyészeti Gyár Rt. | Benzenesulphonamides and process for their preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1518334C3 (en) | 1973-11-15 |
| DE1518334B2 (en) | 1973-04-19 |
| FR4066M (en) | 1966-04-04 |
| NL6515158A (en) | 1966-05-24 |
| DE1518334A1 (en) | 1969-06-12 |
| FR1429306A (en) | 1966-02-25 |
| BE672721A (en) | 1966-05-23 |
| NL139961B (en) | 1973-10-15 |
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