GB1245292A - Halogeno-pregnadienes and process for the manufacture thereof - Google Patents

Halogeno-pregnadienes and process for the manufacture thereof

Info

Publication number
GB1245292A
GB1245292A GB54564/68A GB5456468A GB1245292A GB 1245292 A GB1245292 A GB 1245292A GB 54564/68 A GB54564/68 A GB 54564/68A GB 5456468 A GB5456468 A GB 5456468A GB 1245292 A GB1245292 A GB 1245292A
Authority
GB
United Kingdom
Prior art keywords
double bond
steroids
group
esterified
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB54564/68A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB1245292A publication Critical patent/GB1245292A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01R—ELECTRICALLY-CONDUCTIVE CONNECTIONS; STRUCTURAL ASSOCIATIONS OF A PLURALITY OF MUTUALLY-INSULATED ELECTRICAL CONNECTING ELEMENTS; COUPLING DEVICES; CURRENT COLLECTORS
    • H01R33/00—Coupling devices specially adapted for supporting apparatus and having one part acting as a holder providing support and electrical connection via a counterpart which is structurally associated with the apparatus, e.g. lamp holders; Separate parts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
GB54564/68A 1967-11-17 1968-11-18 Halogeno-pregnadienes and process for the manufacture thereof Expired GB1245292A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1610167A CH510655A (de) 1967-11-17 1967-11-17 Verfahren zur Herstellung neuer Halogenpregnadiene

Publications (1)

Publication Number Publication Date
GB1245292A true GB1245292A (en) 1971-09-08

Family

ID=4414467

Family Applications (1)

Application Number Title Priority Date Filing Date
GB54564/68A Expired GB1245292A (en) 1967-11-17 1968-11-18 Halogeno-pregnadienes and process for the manufacture thereof

Country Status (15)

Country Link
US (1) US3652554A (en:Method)
JP (1) JPS4829221B1 (en:Method)
AT (3) AT298695B (en:Method)
BE (1) BE723905A (en:Method)
BR (1) BR6804024D0 (en:Method)
CH (4) CH513845A (en:Method)
DK (1) DK129835B (en:Method)
FR (2) FR1594773A (en:Method)
GB (1) GB1245292A (en:Method)
MY (1) MY7400317A (en:Method)
NL (1) NL161767C (en:Method)
PL (1) PL80570B1 (en:Method)
SE (1) SE351634B (en:Method)
SU (1) SU424352A3 (en:Method)
YU (4) YU34138B (en:Method)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102827229A (zh) * 2011-06-17 2012-12-19 重庆华邦胜凯制药有限公司 一种纯化卤米松羧酸酯的方法
CN111944004A (zh) * 2020-09-25 2020-11-17 湖南新合新生物医药有限公司 一种卤米松的制备方法

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2010458B2 (de) * 1970-02-28 1979-04-26 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 21-Halogensteroide
CH558787A (de) * 1970-12-10 1975-02-14 Ciba Geigy Ag Verfahren zur herstellung eines neuen halogenpregnadiens.
GB1377608A (en) * 1970-12-17 1974-12-18 Glaxo Lab Ltd 3alpha-hydroxy or acyloxy pregnene-21-ethers
NL7502252A (nl) * 1974-02-27 1975-08-29 Pierrel Spa Werkwijze voor het bereiden van een geneesmid- del met anti-inflammatoire werking, gevormd ge- neesmiddel verkregen volgens deze werkwijze alsmede werkwijze voor het bereiden van in het geneesmiddel gebruikte nieuwe steroiden.
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
FR2291760A1 (fr) * 1974-11-19 1976-06-18 Pierrel Spa Nouveaux steroides a base de 2-chloro-6 b-fluoro-pregna-1,4-diene-3,20-diones
GB1505701A (en) * 1975-06-14 1978-03-30 Pierrel Spa 2-chloro-6beta-fluoropregnanes
DE2655570A1 (de) * 1975-12-12 1977-06-16 Ciba Geigy Ag Neue polyhalogensteroide und verfahren zu ihrer herstellung
WO2005021515A2 (en) * 2003-08-29 2005-03-10 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
US20070259874A1 (en) * 2003-11-26 2007-11-08 Palle Venkata P Phosphodiesterase Inhibitors
WO2007031838A1 (en) 2005-09-16 2007-03-22 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
AU2006305619A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
JP2009512677A (ja) * 2005-10-19 2009-03-26 ランバクシー ラボラトリーズ リミテッド ホスホジエステラーゼタイプｉｖ阻害剤の組成物
WO2008035316A2 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
MX2009003100A (es) * 2006-09-22 2009-05-11 Ranbaxy Lab Ltd Inhibidores de fosfodiesterasa tipo iv.
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
WO2008111009A1 (en) * 2007-03-14 2008-09-18 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
KR101568884B1 (ko) 2007-03-14 2015-11-12 랜박시 래보러터리스 리미티드 포스포디에스테라제 저해제로서 피라졸로 (３,４-ｂ) 피리딘 유도체
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
CN104370987B (zh) * 2014-10-22 2016-09-14 湖南明瑞制药有限公司 一种卤米松的精制方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102827229A (zh) * 2011-06-17 2012-12-19 重庆华邦胜凯制药有限公司 一种纯化卤米松羧酸酯的方法
CN102827229B (zh) * 2011-06-17 2016-01-20 重庆华邦胜凯制药有限公司 一种纯化卤米松羧酸酯的方法
CN111944004A (zh) * 2020-09-25 2020-11-17 湖南新合新生物医药有限公司 一种卤米松的制备方法
CN111944004B (zh) * 2020-09-25 2023-11-17 湖南新合新生物医药有限公司 一种卤米松的制备方法

Also Published As

Publication number Publication date
BR6804024D0 (pt) 1973-01-02
YU267368A (en) 1978-06-30
NL6816337A (en:Method) 1969-05-20
YU34138B (en) 1978-12-31
YU30675A (en) 1982-05-31
DE1807980A1 (de) 1969-06-04
SU424352A3 (en:Method) 1974-04-15
CH534144A (de) 1973-02-28
YU30775A (en) 1982-05-31
NL161767C (nl) 1980-03-17
MY7400317A (en) 1974-12-31
FR1594773A (en:Method) 1970-06-08
FR8278M (en:Method) 1970-11-02
PL80570B1 (en:Method) 1975-08-30
AT293633B (de) 1971-10-25
DK129835C (en:Method) 1975-05-05
CH540244A (de) 1973-08-15
DK129835B (da) 1974-11-25
YU30875A (en) 1982-05-31
AT298695B (de) 1972-05-25
AT298690B (de) 1972-04-15
CH513845A (de) 1971-10-15
US3652554A (en) 1972-03-28
BE723905A (en:Method) 1969-05-14
CH510655A (de) 1971-07-31
SE351634B (en:Method) 1972-12-04
DE1807980B2 (de) 1975-11-06
JPS4829221B1 (en:Method) 1973-09-08

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