FR2291760A1 - Nouveaux steroides a base de 2-chloro-6 b-fluoro-pregna-1,4-diene-3,20-diones - Google Patents

Nouveaux steroides a base de 2-chloro-6 b-fluoro-pregna-1,4-diene-3,20-diones

Info

Publication number
FR2291760A1
FR2291760A1 FR7535284A FR7535284A FR2291760A1 FR 2291760 A1 FR2291760 A1 FR 2291760A1 FR 7535284 A FR7535284 A FR 7535284A FR 7535284 A FR7535284 A FR 7535284A FR 2291760 A1 FR2291760 A1 FR 2291760A1
Authority
FR
France
Prior art keywords
chloro
beta
diones
diene
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7535284A
Other languages
English (en)
Other versions
FR2291760B1 (fr
Inventor
Mario Riva
Luciano Toscano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierrel SpA
Original Assignee
Pierrel SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB31114/75A external-priority patent/GB1505701A/en
Application filed by Pierrel SpA filed Critical Pierrel SpA
Publication of FR2291760A1 publication Critical patent/FR2291760A1/fr
Application granted granted Critical
Publication of FR2291760B1 publication Critical patent/FR2291760B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7535284A 1974-11-19 1975-11-19 Nouveaux steroides a base de 2-chloro-6 b-fluoro-pregna-1,4-diene-3,20-diones Granted FR2291760A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4998274 1974-11-19
GB31114/75A GB1505701A (en) 1975-06-14 1975-06-14 2-chloro-6beta-fluoropregnanes

Publications (2)

Publication Number Publication Date
FR2291760A1 true FR2291760A1 (fr) 1976-06-18
FR2291760B1 FR2291760B1 (fr) 1978-12-01

Family

ID=26257702

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7535284A Granted FR2291760A1 (fr) 1974-11-19 1975-11-19 Nouveaux steroides a base de 2-chloro-6 b-fluoro-pregna-1,4-diene-3,20-diones

Country Status (1)

Country Link
FR (1) FR2291760A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4221786A (en) * 1978-06-20 1980-09-09 Ciba-Geigy Corporation Novel halogenopregnadienes and process for the manufacture thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2014352A1 (fr) * 1968-06-28 1970-04-17 Ciba Geigy Ag
FR1594773A (fr) * 1967-11-17 1970-06-08
DE1921397A1 (de) * 1969-04-23 1970-11-12 Schering Ag Neue 2-Chlor- und 1,2-Dichlorsteriode

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1594773A (fr) * 1967-11-17 1970-06-08
FR2014352A1 (fr) * 1968-06-28 1970-04-17 Ciba Geigy Ag
DE1921397A1 (de) * 1969-04-23 1970-11-12 Schering Ag Neue 2-Chlor- und 1,2-Dichlorsteriode

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4221786A (en) * 1978-06-20 1980-09-09 Ciba-Geigy Corporation Novel halogenopregnadienes and process for the manufacture thereof

Also Published As

Publication number Publication date
FR2291760B1 (fr) 1978-12-01

Similar Documents

Publication Publication Date Title
NO164905C (no) Fremgangsmaate for fremstilling av 16,17-acetal-pregnanderivater.
GB1296458A (fr)
IE39738L (en) Triamcinolone derivative
FR2291760A1 (fr) Nouveaux steroides a base de 2-chloro-6 b-fluoro-pregna-1,4-diene-3,20-diones
GB1291205A (en) A novel pregnane derivative, processes for its preparation, and compositions incorporating it
GB1270614A (en) Stable aqueous steroid phosphate solutions
GB1328998A (en) Process of corticosteroids
FR2291761A1 (fr) Nouveaux steroides et son application pharmacologique
US4444689A (en) 17α-Acyloxy-5β-corticoids and 17α-acyloxy-5α-corticoids
ES348727A1 (es) Un procedimiento para preparar esteroides.
SE332172B (fr)
ES342750A1 (es) Un procedimiento para preparar 21-esteres de esteroides an-ti-inflamatorios de la serie del pregnano.
US3714353A (en) THERAPEUTIC COMPOSITIONS COMPRISING A 6 alpha ; 9 alpha -DIFLUORO-11 beta ,17 alpha ,21-TRIHYDROXY-16 alpha -METHYL-1,4-PREGNADIENE-3,20-DIONE AND 21-ACYLATES
GB898295A (en) Improvements in or relating to steroids and the manufacture thereof
GB1373900A (en) Corticoid ester and method of preparing it
GB1180176A (en) Novel Steroid 21-Esters, their Preparation, and Compositions containing them
JPS51149258A (en) A process for preparing steroid derivatives
US3158628A (en) 21-carbethoxylates of prednisone and prednisolone
GB903049A (en) Steroid compounds, preparation thereof and compositions thereof
US3084175A (en) 15-halo-16 alkyl and alkylene derivatives of the pregnane series
GB1185381A (en) 05,16beta-Methylene Steroids of the 19-Nor-Androstane Series and Process for their Manufacture
GB1223087A (en) Improvements in or relating to new steroid 21-esters, method for their preparation and therapeutic composition containing same
GB1511820A (en) 16-methyl-9alpha-halo steroid ethers and esters and their preparation
GB1192824A (en) Improvements in or relating to 6,7-Methylene and -Halomethylene Steroids
GB1430932A (en) 21-fluoro-pregnanes

Legal Events

Date Code Title Description
ST Notification of lapse