GB0525672D0 - Organic compounds - Google Patents

Organic compounds

Info

Publication number
GB0525672D0
GB0525672D0 GBGB0525672.2A GB0525672A GB0525672D0 GB 0525672 D0 GB0525672 D0 GB 0525672D0 GB 0525672 A GB0525672 A GB 0525672A GB 0525672 D0 GB0525672 D0 GB 0525672D0
Authority
GB
United Kingdom
Prior art keywords
organic compounds
compounds
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0525672.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35736290&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB0525672(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Priority to GBGB0525672.2A priority Critical patent/GB0525672D0/en
Publication of GB0525672D0 publication Critical patent/GB0525672D0/en
Priority to SA6270445A priority patent/SA06270445B1/ar
Priority to JO2006441A priority patent/JO2734B1/en
Priority to KR1020087017171A priority patent/KR101174943B1/ko
Priority to MYPI20081916A priority patent/MY145627A/en
Priority to KR1020127001431A priority patent/KR20120018383A/ko
Priority to SI200631205T priority patent/SI1966209T1/sl
Priority to NZ569013A priority patent/NZ569013A/en
Priority to ARP060105515A priority patent/AR058348A1/es
Priority to PE2006001603A priority patent/PE20070750A1/es
Priority to DK06846986.5T priority patent/DK1966209T3/da
Priority to RU2008128570/04A priority patent/RU2471797C2/ru
Priority to EP11162276A priority patent/EP2361914A1/en
Priority to UAA200808019A priority patent/UA94725C2/ru
Priority to ES06846986T priority patent/ES2375847T3/es
Priority to CN2006800475199A priority patent/CN101331132B/zh
Priority to EP06846986A priority patent/EP1966209B1/en
Priority to TW095146894A priority patent/TWI423965B/zh
Priority to JP2008544876A priority patent/JP5230441B2/ja
Priority to PCT/EP2006/012023 priority patent/WO2007068476A1/en
Priority to US12/097,681 priority patent/US7713976B2/en
Priority to CA2631654A priority patent/CA2631654C/en
Priority to BRPI0619888-0A priority patent/BRPI0619888A2/pt
Priority to PT06846986T priority patent/PT1966209E/pt
Priority to AT06846986T priority patent/ATE529427T1/de
Priority to AU2006326258A priority patent/AU2006326258B2/en
Priority to PL06846986T priority patent/PL1966209T3/pl
Priority to ZA200804628A priority patent/ZA200804628B/xx
Priority to IL191841A priority patent/IL191841A/en
Priority to MA30999A priority patent/MA30027B1/fr
Priority to CR10056A priority patent/CR10056A/es
Priority to EC2008008541A priority patent/ECSP088541A/es
Priority to TNP2008000260A priority patent/TNSN08260A1/en
Priority to NO20082937A priority patent/NO20082937L/no
Priority to HK09101356.7A priority patent/HK1121444A1/xx
Priority to US12/732,646 priority patent/US8048885B2/en
Priority to US13/252,608 priority patent/US8637517B2/en
Priority to CY20111101256T priority patent/CY1112708T1/el
Priority to HR20120030T priority patent/HRP20120030T1/hr
Priority to US14/138,527 priority patent/US20140113908A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
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    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
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    • A61P27/00—Drugs for disorders of the senses
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
GBGB0525672.2A 2005-12-16 2005-12-16 Organic compounds Ceased GB0525672D0 (en)

Priority Applications (40)

Application Number Priority Date Filing Date Title
GBGB0525672.2A GB0525672D0 (en) 2005-12-16 2005-12-16 Organic compounds
SA6270445A SA06270445B1 (ar) 2005-12-16 2006-12-05 مركبات 4-(1h-إندول-5-يل-هتيرو أريلوكسى]-1-أزا-بيسيكلو [1،3.3] نونان
JO2006441A JO2734B1 (en) 2005-12-16 2006-12-10 Organic compounds
AU2006326258A AU2006326258B2 (en) 2005-12-16 2006-12-14 [ (1H- indol- 5 -yl) -heteroaryloxy] - (1-aza-bicyclo [3.3.1] nonanes as cholinergic ligands of the n-AChR for the treatment of psychotic and neurodegenrative disorders.
PL06846986T PL1966209T3 (pl) 2005-12-16 2006-12-14 [1H-Indol-5-ilo)-heteroaryloksy]-(1-aza-bicyklo[3.3.1]nonany jako ligandy cholinergiczne dla nAChR do leczenia zaburzeń psychotycznych i neurodegeneracyjnych
PCT/EP2006/012023 WO2007068476A1 (en) 2005-12-16 2006-12-14 [ (1h- indol- 5 -yl) -heteroaryloxy] - (1-aza-bicyclo [3.3.1] nonanes as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenrative disorders.
BRPI0619888-0A BRPI0619888A2 (pt) 2005-12-16 2006-12-14 [(1h-indol-5-il)-heteroarilóxi]-(1-aza-biciclo[3.3.1]nona nos como ligantes colinérgicos de n-achr para o tratamento de distúrbios psicóticos e neurodegenerativos
KR1020127001431A KR20120018383A (ko) 2005-12-16 2006-12-14 정신병성 및 신경퇴행성 장애의 치료를 위한 ｎ-ａｃｈｒ의 콜린성 리간드로서의 〔(1ｈ-인돌-5-일)-헤테로아릴옥시〕-(1-아자-비시클로〔3.3.1〕노난
SI200631205T SI1966209T1 (sl) 2005-12-16 2006-12-14 ((1H-indol-5-il)-heteroariloksi)-(1-aza-biciklo(3.3.1)nonani kot holinergični ligandi n-AChR za zdravljenje psihotičnih in nevrodegenerativnih motenj
NZ569013A NZ569013A (en) 2005-12-16 2006-12-14 [(1H-indol-5-yl)-heteroaryloxy]-1-aza-bicyclo[3.3.1]nonanes as cholinergic ligands of the N-ACHR for the treatment of psychotic and neurodegenerative disorders
ARP060105515A AR058348A1 (es) 2005-12-16 2006-12-14 Derivados de 1-aza-biciclo-nonano y composiciones farmaceuticas que los comprenden
PE2006001603A PE20070750A1 (es) 2005-12-16 2006-12-14 COMPUESTOS DERIVADOS DE 1-AZA-BICICLONONANO COMO LIGANDOS COLINERGICOS DEL RECEPTOR DE ACETILCOLINA NICOTINICA (nAChR)
DK06846986.5T DK1966209T3 (da) 2005-12-16 2006-12-14 [(1H-Indol-5-yl)-heteroaryloxy]-1-aza-bicyclo(3.3.1]nonaner som cholinergiske ligander af nAChR til behandling af psykotiske og neurodegenerative lidelser
RU2008128570/04A RU2471797C2 (ru) 2005-12-16 2006-12-14 [(1н-индол-5-ил)-гетероарилокси]-1-(азабицикло[3.3.1]нонаны, как холинергические лиганды n-achr, предназначенные для лечения психотических и нейродегенеративных нарушений
EP11162276A EP2361914A1 (en) 2005-12-16 2006-12-14 [(1h-indol-5-yl)-heteroaryloxy]-(1-aza-bicyclo[3.3.1]nonanes as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenrative disorders.
UAA200808019A UA94725C2 (en) 2005-12-16 2006-12-14 [1h- indol- 5 -yl)-heteroaryloxy]-(1-aza-bicyclo [3.3.1] nonanes as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disorders
ES06846986T ES2375847T3 (es) 2005-12-16 2006-12-14 [1h-indol-5-il)heteroariloxi]-(1-aza-biciclo[3.3.1]nonanos como ligandos colinérgicos del n-achr para el tratamiento de trastornos sicóticos y neurodegenerativos.
CN2006800475199A CN101331132B (zh) 2005-12-16 2006-12-14 作为n-achr的胆碱能配体用于治疗精神病和神经变性疾病的[(1h-吲哚-5-基)-杂芳氧基]-(1-氮杂-二环[3.3.1]壬烷
EP06846986A EP1966209B1 (en) 2005-12-16 2006-12-14 [ 1h- indol- 5 -yl) -heteroaryloxy] - (1-aza-bicyclo [3.3.1] nonanes as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disorders
TW095146894A TWI423965B (zh) 2005-12-16 2006-12-14 用於治療精神病和神經退化性疾病之［（１ｈ－吲哚－５－基）雜芳］－１－氮雜雙環［３.３.１］壬烷作為ｎ－ａｃｈｒ膽鹼能配體
JP2008544876A JP5230441B2 (ja) 2005-12-16 2006-12-14 精神病性および神経変性障害の処置のためのｎ−ａｃｈｒのコリン作動性リガンドとしての［（１ｈ−インドール−５−イル）−ヘテロアリールオキシ］−１−アザ−ビシクロ［３．３．１］ノナン
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PT06846986T PT1966209E (pt) 2005-12-16 2006-12-14 [(1h-indol-5-il)-heteroariloxi]-(1-aza-biciclo[3.3.1]nonanos a título de ligandos colinérgicos do n-achr para o tratamento de patologias psicóticas e neurodegenerativas
AT06846986T ATE529427T1 (de) 2005-12-16 2006-12-14 Ä1h-indol-5-yl)-heteroaryloxyü-(1-aza-bicyclo- ä3.3.1ü-nonane als cholinergische liganden des n- achr zur behandlung psychotischer und neurodegenerativer leiden
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IL191841A IL191841A (en) 2005-12-16 2008-05-29 [(1h - indole-5-yl) - heteroaryloxy] - (1-aza-bicyclo [1.3.3]) achr-n cholinergic nonandane for use in the treatment of psychotic and neurodegenerative disorders
MA30999A MA30027B1 (fr) 2005-12-16 2008-06-03 [ (1h- indol- 5 -yl) -heteroaryloxy] - (1-aza-bicyclo [3.3.1] nonanes utilises en tant que ligands cholinergiques de n-achr pour le traitement des troubles psychotiques et neurodegeneratifs
CR10056A CR10056A (es) 2005-12-16 2008-06-09 [(1h-indol-5-il)-heteroariloxi]-(1-aza-biciclo[3.3.1]nonanos como ligandos colinérgicos del n-achr para el tratamiento de trastornos piscóticos y neurodegenerativos
EC2008008541A ECSP088541A (es) 2005-12-16 2008-06-13 [(1h-indol-5-il)-heteroariloxi]-(1-aza-biciclo[3.3.1]nonanos como ligandos colinérgicos del n-achr para el tratamiento de trastornos psicóticos y neurodegenerativos
TNP2008000260A TNSN08260A1 (en) 2005-12-16 2008-06-13 [ (1h- indol- 5 -yl) -heteroaryloxy] - (1-aza-bicyclo [3.3.1] nonanes as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenrative disorders
NO20082937A NO20082937L (no) 2005-12-16 2008-06-30 [(1H-indol-5-yl)-heteroaryloksy]-(1-aza-bicyklo[3 3.1]nonaner som kolinergiske ligander av n-AChR for behandling av psykotiske og neurodegenerative lidelser
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CY20111101256T CY1112708T1 (el) 2005-12-16 2011-12-19 [1η-ινδολο-5-υλο)-ετεροαρυλοξυ]-(1-αζα-δικυκλο[3.3.1]εννεανια ως χολινεργικοι συνδετες του ν-achr για την θεραπεια των ψυχωτικων και νευροεκφυλιστικων διαταραχων
HR20120030T HRP20120030T1 (hr) 2005-12-16 2012-01-10 [(1h-indol-5-il)-heteroariloksi]-(1-aza-biciklo[3.3.1] nonani kao kolinergički ligandi od n-achr za liječenje psihotičkih i neurodegenerativnih poremećaja
US14/138,527 US20140113908A1 (en) 2005-12-16 2013-12-23 [(1h-indol-5-yl) - heteroaryloxy] - (1-aza-bicyclo [3.3.1] nonanes as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenrative disorders

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KR20120018383A (ko) 2012-03-02
KR101174943B1 (ko) 2012-08-17
CA2631654C (en) 2014-05-13
US7713976B2 (en) 2010-05-11
US8048885B2 (en) 2011-11-01
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CR10056A (es) 2008-08-27
IL191841A (en) 2013-11-28
AU2006326258A1 (en) 2007-06-21
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MY145627A (en) 2012-03-15
TWI423965B (zh) 2014-01-21
DK1966209T3 (da) 2012-01-30
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RU2008128570A (ru) 2010-01-27
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JP2009519283A (ja) 2009-05-14
ZA200804628B (en) 2010-10-27
ES2375847T3 (es) 2012-03-06
CN101331132A (zh) 2008-12-24
CN101331132B (zh) 2013-12-04
MA30027B1 (fr) 2008-12-01
PL1966209T3 (pl) 2012-03-30
TNSN08260A1 (en) 2009-10-30
US20100179160A1 (en) 2010-07-15
SA06270445B1 (ar) 2011-10-29
ATE529427T1 (de) 2011-11-15
SI1966209T1 (sl) 2012-01-31
TW200732325A (en) 2007-09-01
EP2361914A1 (en) 2011-08-31
AR058348A1 (es) 2008-01-30
JO2734B1 (en) 2013-09-15
PE20070750A1 (es) 2007-08-28
AU2006326258B2 (en) 2011-06-09
JP5230441B2 (ja) 2013-07-10
UA94725C2 (en) 2011-06-10
US8637517B2 (en) 2014-01-28
IL191841A0 (en) 2008-12-29
KR20080077018A (ko) 2008-08-20
HRP20120030T1 (hr) 2012-02-29
US20140113908A1 (en) 2014-04-24
ECSP088541A (es) 2008-07-30
US20080293731A1 (en) 2008-11-27
BRPI0619888A2 (pt) 2011-10-25
WO2007068476A1 (en) 2007-06-21

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