ATE254618T1 - Spiro chinuclidin-derivate, ihre herstellung und verwendung - Google Patents
Spiro chinuclidin-derivate, ihre herstellung und verwendungInfo
- Publication number
- ATE254618T1 ATE254618T1 AT98921380T AT98921380T ATE254618T1 AT E254618 T1 ATE254618 T1 AT E254618T1 AT 98921380 T AT98921380 T AT 98921380T AT 98921380 T AT98921380 T AT 98921380T AT E254618 T1 ATE254618 T1 AT E254618T1
- Authority
- AT
- Austria
- Prior art keywords
- spiro
- preparation
- quinuclidine derivatives
- compounds
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK62697 | 1997-05-30 | ||
PCT/DK1998/000227 WO1998054189A1 (en) | 1997-05-30 | 1998-05-29 | Spiro-quinuclidine derivatives, their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE254618T1 true ATE254618T1 (de) | 2003-12-15 |
Family
ID=8095721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98921380T ATE254618T1 (de) | 1997-05-30 | 1998-05-29 | Spiro chinuclidin-derivate, ihre herstellung und verwendung |
Country Status (11)
Country | Link |
---|---|
US (1) | US6352995B1 (de) |
EP (1) | EP0984970B1 (de) |
JP (1) | JP2002500652A (de) |
CN (1) | CN1110499C (de) |
AT (1) | ATE254618T1 (de) |
AU (1) | AU744368B2 (de) |
CA (1) | CA2289578A1 (de) |
DE (1) | DE69819891T2 (de) |
NZ (1) | NZ500643A (de) |
WO (1) | WO1998054189A1 (de) |
ZA (1) | ZA984637B (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2790474B1 (fr) * | 1999-03-05 | 2001-04-06 | Synthelabo | Derives de pyridopyranoazepines, leur preparation et leur application en therapeutique |
US6492385B2 (en) | 2000-08-18 | 2002-12-10 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
AU2001282875A1 (en) | 2000-08-21 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
AU2001284646A1 (en) | 2000-08-21 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
JP2004506734A (ja) * | 2000-08-21 | 2004-03-04 | ファルマシア・アンド・アップジョン・カンパニー | 疾患治療用のキヌクリド置換ヘテロアリール部分 |
DK1397366T3 (da) * | 2001-06-01 | 2007-05-07 | Astrazeneca Ab | Hidtil ukendt ligander for nicotinacetylcholinreceptorer egnede i terapi |
US6569865B2 (en) | 2001-06-01 | 2003-05-27 | Astrazeneca Ab | Spiro 1-azabicyclo[2.2.2]octane-3,2′(3′h)-furo[2,3-b]pyridine |
JP2005511613A (ja) | 2001-11-08 | 2005-04-28 | ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー | 疾患治療用アザビシクロ置換ヘテロアリール化合物 |
EP1542999A1 (de) | 2002-08-01 | 2005-06-22 | Pharmacia & Upjohn Company LLC | 1h-pyrazol- und 1h-pyrrol-azabicyclische verbindungen mit alpha-7-nachr-aktivität |
GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
IL155666A (en) * | 2003-04-29 | 2013-12-31 | Neurim Pharma 1991 | Insomnia treatment |
US9119846B2 (en) | 2003-04-29 | 2015-09-01 | Neurim Pharmaceuticals (1991) Ltd. | Method and composition for enhancing cognition in alzheimer's patients |
US20050137217A1 (en) * | 2003-12-22 | 2005-06-23 | Jianguo Ji | Spirocyclic quinuclidinic ether derivatives |
US7045530B2 (en) | 2003-12-22 | 2006-05-16 | Abbott Laboratories | Spirocyclic quinuclidinic ether derivatives |
PE20060437A1 (es) | 2004-06-18 | 2006-06-08 | Novartis Ag | COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR |
GB0415746D0 (en) | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
EP1802258A4 (de) | 2004-09-13 | 2015-09-23 | Chrono Therapeutics Inc | Biosynchrone transdermale arzneiabgabe |
GB0521508D0 (en) | 2005-10-21 | 2005-11-30 | Novartis Ag | Organic compounds |
GB0525672D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
GB0525673D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
ES2521494T3 (es) | 2007-04-02 | 2014-11-12 | Parkinson's Institute | Métodos y composiciones para la reducción de los efectos secundarios de tratamientos terapéuticos |
AU2016211330A1 (en) | 2015-01-28 | 2017-08-03 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
WO2018129304A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
EP3801732A4 (de) | 2018-05-29 | 2022-04-27 | Morningside Venture Investments Limited | Verfahren und systeme zur wirkstofffreisetzung |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL48452A (en) | 1975-11-11 | 1979-07-25 | Purdue Frederick Co | Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them |
IL87234A (en) | 1987-08-13 | 1992-02-16 | Israel Inst Biolog Res | Optical isomers of 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine,their preparation and pharmaceutical compositions containing them |
ES2074441T3 (es) | 1987-10-05 | 1995-09-16 | Yamanouchi Pharma Co Ltd | Compuestos espiro heterociclicos y su preparacion. |
US4876260A (en) | 1987-10-28 | 1989-10-24 | State Of Israel, Israel Institute Of Biological Research | Oxathiolanes |
GB8816299D0 (en) * | 1988-07-08 | 1988-08-10 | Merck Sharp & Dohme | Therapeutic agents |
US5534520A (en) | 1990-04-10 | 1996-07-09 | Fisher; Abraham | Spiro compounds containing five-membered rings |
US5803081A (en) * | 1996-06-28 | 1998-09-08 | Regent Court Technologies | Tobacco and related products |
AR013184A1 (es) | 1997-07-18 | 2000-12-13 | Astrazeneca Ab | Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis |
-
1998
- 1998-05-29 NZ NZ500643A patent/NZ500643A/en unknown
- 1998-05-29 JP JP50013299A patent/JP2002500652A/ja not_active Withdrawn
- 1998-05-29 CN CN98805414A patent/CN1110499C/zh not_active Expired - Fee Related
- 1998-05-29 AT AT98921380T patent/ATE254618T1/de not_active IP Right Cessation
- 1998-05-29 AU AU74263/98A patent/AU744368B2/en not_active Ceased
- 1998-05-29 ZA ZA984637A patent/ZA984637B/xx unknown
- 1998-05-29 EP EP98921380A patent/EP0984970B1/de not_active Expired - Lifetime
- 1998-05-29 CA CA002289578A patent/CA2289578A1/en not_active Abandoned
- 1998-05-29 DE DE69819891T patent/DE69819891T2/de not_active Expired - Lifetime
- 1998-05-29 WO PCT/DK1998/000227 patent/WO1998054189A1/en active IP Right Grant
-
1999
- 1999-10-14 US US09/417,889 patent/US6352995B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0984970A1 (de) | 2000-03-15 |
WO1998054189A1 (en) | 1998-12-03 |
US6352995B1 (en) | 2002-03-05 |
AU7426398A (en) | 1998-12-30 |
DE69819891T2 (de) | 2004-08-26 |
AU744368B2 (en) | 2002-02-21 |
CN1257506A (zh) | 2000-06-21 |
DE69819891D1 (de) | 2003-12-24 |
CA2289578A1 (en) | 1998-12-03 |
EP0984970B1 (de) | 2003-11-19 |
NZ500643A (en) | 2001-12-21 |
ZA984637B (en) | 1998-12-21 |
CN1110499C (zh) | 2003-06-04 |
JP2002500652A (ja) | 2002-01-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |