NO20082937L - [(1H-indol-5-yl)-heteroaryloksy]-(1-aza-bicyklo[3 3.1]nonaner som kolinergiske ligander av n-AChR for behandling av psykotiske og neurodegenerative lidelser - Google Patents

[(1H-indol-5-yl)-heteroaryloksy]-(1-aza-bicyklo[3 3.1]nonaner som kolinergiske ligander av n-AChR for behandling av psykotiske og neurodegenerative lidelser

Info

Publication number
NO20082937L
NO20082937L NO20082937A NO20082937A NO20082937L NO 20082937 L NO20082937 L NO 20082937L NO 20082937 A NO20082937 A NO 20082937A NO 20082937 A NO20082937 A NO 20082937A NO 20082937 L NO20082937 L NO 20082937L
Authority
NO
Norway
Prior art keywords
nonanes
achr
psychotic
heteroaryloxy
indol
Prior art date
Application number
NO20082937A
Other languages
English (en)
Inventor
Dominik Feuerbach
Bernard Lucien Roy
Konstanze Hurth
Mathias Frederiksen
Beatrix Wagner
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35736290&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20082937(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20082937L publication Critical patent/NO20082937L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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NO20082937A 2005-12-16 2008-06-30 [(1H-indol-5-yl)-heteroaryloksy]-(1-aza-bicyklo[3 3.1]nonaner som kolinergiske ligander av n-AChR for behandling av psykotiske og neurodegenerative lidelser NO20082937L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0525672.2A GB0525672D0 (en) 2005-12-16 2005-12-16 Organic compounds
PCT/EP2006/012023 WO2007068476A1 (en) 2005-12-16 2006-12-14 [ (1h- indol- 5 -yl) -heteroaryloxy] - (1-aza-bicyclo [3.3.1] nonanes as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenrative disorders.

Publications (1)

Publication Number Publication Date
NO20082937L true NO20082937L (no) 2008-07-16

Family

ID=35736290

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082937A NO20082937L (no) 2005-12-16 2008-06-30 [(1H-indol-5-yl)-heteroaryloksy]-(1-aza-bicyklo[3 3.1]nonaner som kolinergiske ligander av n-AChR for behandling av psykotiske og neurodegenerative lidelser

Country Status (35)

Country Link
US (4) US7713976B2 (no)
EP (2) EP1966209B1 (no)
JP (1) JP5230441B2 (no)
KR (2) KR101174943B1 (no)
CN (1) CN101331132B (no)
AR (1) AR058348A1 (no)
AT (1) ATE529427T1 (no)
AU (1) AU2006326258B2 (no)
BR (1) BRPI0619888A2 (no)
CA (1) CA2631654C (no)
CR (1) CR10056A (no)
CY (1) CY1112708T1 (no)
DK (1) DK1966209T3 (no)
EC (1) ECSP088541A (no)
ES (1) ES2375847T3 (no)
GB (1) GB0525672D0 (no)
HK (1) HK1121444A1 (no)
HR (1) HRP20120030T1 (no)
IL (1) IL191841A (no)
JO (1) JO2734B1 (no)
MA (1) MA30027B1 (no)
MY (1) MY145627A (no)
NO (1) NO20082937L (no)
NZ (1) NZ569013A (no)
PE (1) PE20070750A1 (no)
PL (1) PL1966209T3 (no)
PT (1) PT1966209E (no)
RU (1) RU2471797C2 (no)
SA (1) SA06270445B1 (no)
SI (1) SI1966209T1 (no)
TN (1) TNSN08260A1 (no)
TW (1) TWI423965B (no)
UA (1) UA94725C2 (no)
WO (1) WO2007068476A1 (no)
ZA (1) ZA200804628B (no)

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GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
PE20060437A1 (es) 2004-06-18 2006-06-08 Novartis Ag COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
TWI403320B (zh) 2005-12-16 2013-08-01 Infinity Discovery Inc 用於抑制ｂｃｌ蛋白和結合夥伴間之交互作用的化合物及方法
CN102573842A (zh) * 2009-07-23 2012-07-11 诺瓦提斯公司 氮杂双环烷基衍生物或吡咯烷-2-酮衍生物的用途
TWI558398B (zh) 2009-09-22 2016-11-21 諾華公司 菸鹼乙醯膽鹼受體α７活化劑之用途
CA2782361C (en) * 2009-12-17 2018-01-16 Abbott Laboratories Bridgehead amine ring-fused indoles and indolines useful to treat neurodegenerative and neuropsychiatric disorders
MX2013008704A (es) 2011-01-27 2013-08-21 Novartis Ag Uso de activadores del receptor de acetil-colina nicotinico alfa-7.
MX2013010698A (es) 2011-03-18 2014-02-17 Novartis Ag Combinaciones de activadores del receptor de acetil-colina nicotinico alfa-7 y antagonistas del receptor de glutamato metabotropico 5 (mglur5) para usarse en la discinesia inducida por dopamina en la enfermedad de parkinson.
AU2012324458B2 (en) 2011-10-20 2016-05-19 Novartis Ag Biomarkers predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
EP2931315B1 (en) 2012-12-11 2017-11-29 Novartis AG Biomarker predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
ES2883232T3 (es) 2013-01-15 2021-12-07 Novartis Ag Uso de agonistas del receptor nicotínico de acetilcolina alfa 7
JP6137336B2 (ja) 2013-01-15 2017-05-31 ノバルティス アーゲー ナルコレプシーの処置のためのアルファ７ニコチン性受容体アゴニストの使用
US20150313884A1 (en) 2013-01-15 2015-11-05 Novartis Ag Use of alpha 7 nicotinic acetylcholine receptor agonists
KR101879919B1 (ko) 2013-01-15 2018-07-18 노파르티스 아게 알파 7 니코틴성 아세틸콜린 수용체 작용물질의 용도

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