GB0018973D0 - Synthesis of chiral cyanohydrins - Google Patents

Synthesis of chiral cyanohydrins

Info

Publication number
GB0018973D0
GB0018973D0 GBGB0018973.8A GB0018973A GB0018973D0 GB 0018973 D0 GB0018973 D0 GB 0018973D0 GB 0018973 A GB0018973 A GB 0018973A GB 0018973 D0 GB0018973 D0 GB 0018973D0
Authority
GB
United Kingdom
Prior art keywords
chiral
synthesis
aldehyde
leaving group
catalyst
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0018973.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OF SCIENCES
Kings College London
AN Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences INEOS RAS
Original Assignee
OF SCIENCES
Kings College London
AN Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences INEOS RAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OF SCIENCES, Kings College London, AN Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences INEOS RAS filed Critical OF SCIENCES
Priority to GBGB0018973.8A priority Critical patent/GB0018973D0/en
Publication of GB0018973D0 publication Critical patent/GB0018973D0/en
Priority to HU0301824A priority patent/HUP0301824A3/hu
Priority to AU2001275740A priority patent/AU2001275740A1/en
Priority to AT01953252T priority patent/ATE323069T1/de
Priority to KR1020037001417A priority patent/KR100820273B1/ko
Priority to MXPA03000903A priority patent/MXPA03000903A/es
Priority to DE60118752A priority patent/DE60118752D1/de
Priority to EP01953252A priority patent/EP1307427B3/en
Priority to CZ2003276A priority patent/CZ2003276A3/cs
Priority to PT01953252T priority patent/PT1307427E/pt
Priority to DE60118752T priority patent/DE60118752T4/de
Priority to ES01953252T priority patent/ES2262665T7/es
Priority to PCT/GB2001/003456 priority patent/WO2002010095A2/en
Priority to DK01953252T priority patent/DK1307427T5/da
Priority to HK04105060.0A priority patent/HK1062008B/xx
Priority to CNB018167209A priority patent/CN100406433C/zh
Priority to JP2002516228A priority patent/JP2004505097A/ja
Priority to CA002418116A priority patent/CA2418116A1/en
Priority to US10/354,964 priority patent/US6897332B2/en
Priority to US11/114,068 priority patent/US7314844B2/en
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/22—Organic complexes
    • B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
    • B01J31/2208—Oxygen, e.g. acetylacetonates
    • B01J31/2226—Anionic ligands, i.e. the overall ligand carries at least one formal negative charge
    • B01J31/2243—At least one oxygen and one nitrogen atom present as complexing atoms in an at least bidentate or bridging ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B43/00—Formation or introduction of functional groups containing nitrogen
    • C07B43/08—Formation or introduction of functional groups containing nitrogen of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/30—Addition reactions at carbon centres, i.e. to either C-C or C-X multiple bonds
    • B01J2231/34—Other additions, e.g. Monsanto-type carbonylations, addition to 1,2-C=X or 1,2-C-X triplebonds, additions to 1,4-C=C-C=X or 1,4-C=-C-X triple bonds with X, e.g. O, S, NH/N
    • B01J2231/341—1,2-additions, e.g. aldol or Knoevenagel condensations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/02—Compositional aspects of complexes used, e.g. polynuclearity
    • B01J2531/0202—Polynuclearity
    • B01J2531/0205—Bi- or polynuclear complexes, i.e. comprising two or more metal coordination centres, without metal-metal bonds, e.g. Cp(Lx)Zr-imidazole-Zr(Lx)Cp
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/02—Compositional aspects of complexes used, e.g. polynuclearity
    • B01J2531/0238—Complexes comprising multidentate ligands, i.e. more than 2 ionic or coordinative bonds from the central metal to the ligand, the latter having at least two donor atoms, e.g. N, O, S, P
    • B01J2531/0241—Rigid ligands, e.g. extended sp2-carbon frameworks or geminal di- or trisubstitution
    • B01J2531/0252—Salen ligands or analogues, e.g. derived from ethylenediamine and salicylaldehyde
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/40—Complexes comprising metals of Group IV (IVA or IVB) as the central metal
    • B01J2531/46—Titanium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/50—Complexes comprising metals of Group V (VA or VB) as the central metal
    • B01J2531/56—Vanadium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Manufacture And Refinement Of Metals (AREA)
GBGB0018973.8A 2000-08-02 2000-08-02 Synthesis of chiral cyanohydrins Ceased GB0018973D0 (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
GBGB0018973.8A GB0018973D0 (en) 2000-08-02 2000-08-02 Synthesis of chiral cyanohydrins
CA002418116A CA2418116A1 (en) 2000-08-02 2001-08-01 Process for the cyanation of aldehydes
CZ2003276A CZ2003276A3 (cs) 2000-08-02 2001-08-01 Způsob kyanace aldehydů a kompozice pro tento způsob
DE60118752T DE60118752T4 (de) 2000-08-02 2001-08-01 Verfahren zur cyanierung von aldehyden
AT01953252T ATE323069T1 (de) 2000-08-02 2001-08-01 Verfahren zur cyanierung von aldehyden
KR1020037001417A KR100820273B1 (ko) 2000-08-02 2001-08-01 알데하이드의 시안화 방법
MXPA03000903A MXPA03000903A (es) 2000-08-02 2001-08-01 Proceso para cianacion de aldehidos.
DE60118752A DE60118752D1 (de) 2000-08-02 2001-08-01 Verfahren zur cyanierung von aldehyden
EP01953252A EP1307427B3 (en) 2000-08-02 2001-08-01 Process for the cyanation of aldehydes
HU0301824A HUP0301824A3 (en) 2000-08-02 2001-08-01 Process for the cyanation of aldehydes
PT01953252T PT1307427E (pt) 2000-08-02 2001-08-01 Processo para a cianacao de aldeidos
AU2001275740A AU2001275740A1 (en) 2000-08-02 2001-08-01 Process for the cyanation of aldehydes
ES01953252T ES2262665T7 (es) 2000-08-02 2001-08-01 Procedimiento para la cianuracion de aldehidos.
PCT/GB2001/003456 WO2002010095A2 (en) 2000-08-02 2001-08-01 Process for the cyanation of aldehydes
DK01953252T DK1307427T5 (da) 2000-08-02 2001-08-01 Fremgangsmåde til cyanering af aldehyder
HK04105060.0A HK1062008B (en) 2000-08-02 2001-08-01 Process for the cyanation of aldehydes
CNB018167209A CN100406433C (zh) 2000-08-02 2001-08-01 醛的氰化方法
JP2002516228A JP2004505097A (ja) 2000-08-02 2001-08-01 アルデヒド類のシアン化方法
US10/354,964 US6897332B2 (en) 2000-08-02 2003-01-31 Process for the cyanation of aldehydes
US11/114,068 US7314844B2 (en) 2000-08-02 2005-04-26 Process for the cyanation aldehydes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0018973.8A GB0018973D0 (en) 2000-08-02 2000-08-02 Synthesis of chiral cyanohydrins

Publications (1)

Publication Number Publication Date
GB0018973D0 true GB0018973D0 (en) 2000-09-20

Family

ID=9896847

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0018973.8A Ceased GB0018973D0 (en) 2000-08-02 2000-08-02 Synthesis of chiral cyanohydrins

Country Status (16)

Country Link
EP (1) EP1307427B3 (enExample)
JP (1) JP2004505097A (enExample)
KR (1) KR100820273B1 (enExample)
CN (1) CN100406433C (enExample)
AT (1) ATE323069T1 (enExample)
AU (1) AU2001275740A1 (enExample)
CA (1) CA2418116A1 (enExample)
CZ (1) CZ2003276A3 (enExample)
DE (2) DE60118752T4 (enExample)
DK (1) DK1307427T5 (enExample)
ES (1) ES2262665T7 (enExample)
GB (1) GB0018973D0 (enExample)
HU (1) HUP0301824A3 (enExample)
MX (1) MXPA03000903A (enExample)
PT (1) PT1307427E (enExample)
WO (1) WO2002010095A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0212017D0 (en) * 2002-05-24 2002-07-03 King S College London Catalyst and process
GB0103857D0 (en) 2001-02-16 2001-04-04 Avecia Ltd Preparation of chloromandelic acid
DE10131810A1 (de) * 2001-06-30 2003-02-27 Clariant Gmbh Verfahren zur Herstellung von optisch aktiven Cyanhydrinen und deren korrespondierenden Säuren
DE10131811A1 (de) * 2001-06-30 2003-04-03 Clariant Gmbh Optisch aktive Katalysatoren
US8828902B2 (en) 2001-07-12 2014-09-09 Reaxa Limited Microencapsulated catalyst methods of preparation and method of use thereof
DE10259162A1 (de) * 2002-12-18 2004-07-08 Clariant Gmbh Optisch aktive Komplexe enthaltende Mischungen
ATE444281T1 (de) 2004-10-15 2009-10-15 Mitsui Chemicals Inc Titanverbindung und verfahren zur herstellung optisch aktiver cyanhydrine
WO2007105658A1 (ja) * 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 光学活性クロメンオキシド化合物の製造方法
CN101437827B (zh) * 2006-03-10 2012-08-29 日产化学工业株式会社 光学活性色烯氧化物化合物的制造方法
WO2008121074A1 (en) * 2007-03-29 2008-10-09 Agency For Science, Technology And Research Method of producing an optically active cyanohydrin derivative
CN102234291B (zh) * 2010-04-23 2014-10-15 中国科学院上海有机化学研究所 桥连双希夫碱钛络合物、合成方法及其应用
CN106552671A (zh) * 2015-09-25 2017-04-05 沈阳中化农药化工研发有限公司 一种多相催化剂及其制备和应用
CN116987004B (zh) * 2023-09-27 2023-12-12 新华制药（寿光）有限公司 一种3-(3,4-二甲氧基苯基)-2-氨基-2-甲基丙腈的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2919974A1 (de) * 1979-05-17 1980-11-27 Hoechst Ag Verfahren zur herstellung von cyanhydrinacylaten von aldehyden
JPH0429965A (ja) * 1990-05-28 1992-01-31 Katakura Chitsukarin Kk α―Ｎ―アルキルアミノニトリル誘導体鏡像異性体の製造方法
JP3303327B2 (ja) * 1992-03-18 2002-07-22 住友化学工業株式会社 不斉誘起触媒
US5349079A (en) * 1992-12-14 1994-09-20 Akzo Nobel Nv Process for forming α-aminonitriles from carbonyl compound and fatty amine hydrohalide
JPH06271522A (ja) * 1993-01-21 1994-09-27 Sumitomo Chem Co Ltd 光学活性シアノヒドリンエステルの製造方法
JPH0770040A (ja) * 1993-06-22 1995-03-14 Sumitomo Chem Co Ltd 光学活性シアノヒドリンエステルの製造法

Also Published As

Publication number Publication date
DK1307427T3 (da) 2006-07-31
KR20030022339A (ko) 2003-03-15
WO2002010095A2 (en) 2002-02-07
JP2004505097A (ja) 2004-02-19
WO2002010095A3 (en) 2002-04-18
KR100820273B1 (ko) 2008-04-07
DE60118752T2 (de) 2007-03-15
MXPA03000903A (es) 2004-08-02
HUP0301824A3 (en) 2005-11-28
ES2262665T3 (es) 2006-12-01
PT1307427E (pt) 2006-07-31
CN100406433C (zh) 2008-07-30
EP1307427B3 (en) 2009-04-29
ATE323069T1 (de) 2006-04-15
ES2262665T7 (es) 2009-11-05
HK1062008A1 (zh) 2004-10-15
CA2418116A1 (en) 2002-02-07
DE60118752D1 (de) 2006-05-24
AU2001275740A1 (en) 2002-02-13
EP1307427A2 (en) 2003-05-07
CN1468212A (zh) 2004-01-14
DK1307427T5 (da) 2009-06-15
CZ2003276A3 (cs) 2003-05-14
EP1307427B1 (en) 2006-04-12
DE60118752T4 (de) 2009-10-22
HUP0301824A2 (hu) 2003-09-29

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)