FR2550706A1 - - Google Patents

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Publication number
FR2550706A1
FR2550706A1 FR8412930A FR8412930A FR2550706A1 FR 2550706 A1 FR2550706 A1 FR 2550706A1 FR 8412930 A FR8412930 A FR 8412930A FR 8412930 A FR8412930 A FR 8412930A FR 2550706 A1 FR2550706 A1 FR 2550706A1
Authority
FR
France
Prior art keywords
chamber
constituents
component
mixing chamber
aerosol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8412930A
Other languages
English (en)
French (fr)
Other versions
FR2550706B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sterwin AG
Original Assignee
Sterwin AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterwin AG filed Critical Sterwin AG
Publication of FR2550706A1 publication Critical patent/FR2550706A1/fr
Application granted granted Critical
Publication of FR2550706B1 publication Critical patent/FR2550706B1/fr
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR8412930A 1983-08-17 1984-08-17 Expired FR2550706B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838322178A GB8322178D0 (en) 1983-08-17 1983-08-17 Preparing aerosol compositions

Publications (2)

Publication Number Publication Date
FR2550706A1 true FR2550706A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1985-02-22
FR2550706B1 FR2550706B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-09-23

Family

ID=10547457

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8412930A Expired FR2550706B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-08-17 1984-08-17

Country Status (22)

Country Link
JP (1) JPS6089414A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR850001689A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT389993B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU569314B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE900375A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH667384B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3430385A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK163479C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8506445A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI85214C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2550706B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (2) GB8322178D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR80127B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE57537B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL72590A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1175612B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU85512A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8402514A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ209112A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT79104B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE459471B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA846064B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158441A3 (en) * 1984-03-08 1986-05-21 Phares Pharmaceutical Research N.V. Liposome-forming composition
WO1987001586A1 (en) * 1985-09-17 1987-03-26 Biocompatibles Limited Aerosol
EP0190926A3 (en) * 1985-02-05 1987-09-02 Sterwin Ag. A method for the preparation of liposomes, a pack for use therein and a composition for use in preparing a liposomal material
EP0221821A3 (en) * 1985-11-01 1988-01-27 Centre National De La Recherche Scientifique (Cnrs) New aerosol composition for in vivo imaging and therapy
FR2638639A1 (fr) * 1988-11-08 1990-05-11 Parincos Parfumerie Cosmet Int Composition et procede d'obtention de liposomes oligolamellaires en vue d'une application en cosmetologie et dermatologie topique
EP0616801A1 (de) * 1993-03-24 1994-09-28 Ciba-Geigy Ag Verfahren zur Herstellung einer Liposomendispersion im Hochdruckbereich
WO1995031172A1 (en) * 1994-05-16 1995-11-23 Phares Pharmaceutical Holland B.V. Liposome forming compositions
ES2111488A1 (es) * 1996-01-17 1998-03-01 Lucas Meyer S A Utilizacion de composiciones proliposomas en la tintura, blanqueo y suavizado de la industrial textil y procedimiento para la preparacion de ba¦os de tintura a partir de dichas composiciones proliposomas.
WO2007049278A3 (en) * 2005-10-26 2007-09-13 Yissum Res Dev Co A method for preparing liposomes and uses thereof

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GB8423436D0 (en) * 1984-09-17 1984-10-24 Riker Laboratories Inc Preparation of liposomes
CA1260393A (en) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes of synthetic lipids
US5192528A (en) 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
AU587472B2 (en) * 1985-05-22 1989-08-17 Liposome Technology, Inc. Liposome inhalation method and system
US5340587A (en) * 1985-05-22 1994-08-23 Liposome Technology, Inc. Liposome/bronchodilator method & System
IE63869B1 (en) * 1986-11-06 1995-06-14 Res Dev Foundation Aerosols containing liposomes and method for their preparation
US4897256A (en) * 1986-11-25 1990-01-30 Abbott Laboratories LHRH analog formulations
US4828837A (en) * 1987-03-30 1989-05-09 Liposome Technology, Inc. Non-crystalline minoxidil composition, its production and application
US5030442A (en) * 1987-03-30 1991-07-09 Liposome Technology, Inc. Non-crystalline minoxidil composition
JP2581920B2 (ja) * 1987-05-18 1997-02-19 有限会社野々川商事 化粧料
JPH03193714A (ja) * 1989-12-25 1991-08-23 Kobayashi Kose Co Ltd エアゾール型化粧料
DE4203306A1 (de) * 1992-02-06 1993-08-12 Ig Spruehtechnik Gmbh Asthma oder pulmonal-aerosolzubereitungen mit lecithin
CA2163860A1 (en) * 1993-06-30 1995-01-12 Chung C. Hsu Method for preparing liposomes
WO1998055104A1 (fr) * 1997-06-06 1998-12-10 Shionogi & Co., Ltd. Perfectionnement d'un systeme d'administration de medicament
EP1013268A1 (en) * 1998-06-30 2000-06-28 Rohto Pharmaceutical Co., Ltd. Compositions containing liposomes and/or emulsions and process for the preparation thereof
EP1839648A3 (en) * 1998-11-12 2007-11-21 Transave, Inc. An inhalation system
WO2000027359A1 (en) * 1998-11-12 2000-05-18 Pilkiewicz Frank G An inhalation system
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US7879351B2 (en) 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
HUE025491T2 (en) 2002-10-29 2016-04-28 Insmed Inc Delayed release of anti-infective agents
CA2896083A1 (en) 2005-12-08 2007-06-14 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
CA2649025A1 (en) * 2006-04-11 2007-10-18 Wingturf Co., Ltd. Production method of liposome dispersion and production equipment thereof
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
JP5572636B2 (ja) * 2008-12-29 2014-08-13 ペトロヴィッチ グレベンニコヴ,イヴゲニー リポソーム医薬の製造方法及びリポソーム製造装置
RU2470624C1 (ru) * 2011-08-25 2012-12-27 Евгений Петрович Гребенников Устройство для получения липосомальных препаратов
EP4005576B1 (en) 2012-05-21 2023-12-13 Insmed Incorporated Systems for treating pulmonary infections
MX2015006681A (es) 2012-11-29 2016-04-06 Insmed Inc Formulaciones de vancomicina estabilizadas.
US20150224077A1 (en) 2014-02-10 2015-08-13 Patara Pharma, LLC Methods for the Treatment of Systemic Disorders Treatable with Mast Cell Stabilizers, including Mast Cell Related Disorders
WO2015120392A1 (en) 2014-02-10 2015-08-13 Patara Pharma, LLC Mast cell stabilizers for lung disease treatment
KR102489036B1 (ko) 2014-05-15 2023-01-13 인스메드 인코포레이티드 폐의 비-결핵성 마이코박테리아 감염을 치료하기 위한 방법
US10238625B2 (en) 2015-08-07 2019-03-26 Respivant Sciences Gmbh Methods for the treatment of mast cell related disorders with mast cell stabilizers
US10265296B2 (en) 2015-08-07 2019-04-23 Respivant Sciences Gmbh Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders
CN110139646A (zh) 2016-08-31 2019-08-16 瑞思皮万特科学有限责任公司 用于治疗由特发性肺纤维化引起的慢性咳嗽的色甘酸组合物
JP2019531308A (ja) 2016-10-07 2019-10-31 レシュピファント サイエンシス ゲゼルシャフト ミット ベシュレンクター ハフトゥングRespivant Sciences Gmbh 肺線維症の治療のためのクロモリン組成物
JP7008975B2 (ja) * 2017-08-31 2022-01-25 クラシエホームプロダクツ株式会社 皮膚化粧料
WO2019191627A1 (en) 2018-03-30 2019-10-03 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
US12121073B2 (en) * 2020-07-17 2024-10-22 Kt&G Corporation Pressurization device for aerosol generating article and aerosol generating system including the same

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US3325056A (en) * 1966-02-23 1967-06-13 Du Pont Apparatus for codispensing a plurality of liquids
US3326416A (en) * 1966-01-14 1967-06-20 Du Pont Apparatus for codispensing a plurality of liquids
US3338479A (en) * 1966-04-04 1967-08-29 Leonard L Marraffino Mixing head with secondary fluid adapted for connection with discharge means of primary fluid container
FR2024210A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1968-11-25 1970-08-28 Gillette Co
US3594476A (en) * 1969-05-12 1971-07-20 Massachusetts Inst Technology Submicron aqueous aerosols containing lecithin
FR2122149A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1971-01-16 1972-08-25 Wilkinson Sword Ltd
GB1302671A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1970-08-29 1973-01-10
DE2346730A1 (de) * 1973-09-17 1975-04-17 Heyer Gmbh Carl Geraet zur herstellung eines programmierten therapeutischen aerosolregimes
DE2818655A1 (de) * 1977-05-10 1978-11-23 Ici Ltd Liposome
GB2001334A (en) * 1977-07-19 1979-01-31 Fisons Ltd Pressurised aerosol formulation
GB2013609A (en) * 1978-02-02 1979-08-15 Oreal Storage stability of aqueous dispersions of spherules
WO1981003318A1 (en) * 1980-05-12 1981-11-26 Polyfill Ag Pressurized tank
EP0087814A1 (de) * 1982-03-01 1983-09-07 Perfect-Valois Ventil GmbH Abgabeventil für Aerosoldosen
EP0100964A2 (de) * 1982-07-31 1984-02-22 Reifenrath, Rainer, Dr. Pharmazeutisches Erzeugnis zur Behandlung und Prophylaxe von Infektionen sowie von Husten und obstruktiven Atemwegserkrankungen sowie Verfahren zu seiner Herstellung
GB2136762A (en) * 1983-03-22 1984-09-26 Oreal Process for preparing lipid vesicles by vaporisation of solvents
EP0137897A1 (de) * 1983-08-16 1985-04-24 Sterwin Ag. Zweikomponentenpackung

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DE1277210B (de) * 1965-09-24 1968-09-12 Revlon Selbsttreibende Gemische
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DE2115926C3 (de) * 1971-04-01 1978-05-03 C.H. Boehringer Sohn, 6507 Ingelheim 1 -(4-Hydroxy-3-dimethylaminosuIfamidophenyI)-2-aminoäthanderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
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US3326416A (en) * 1966-01-14 1967-06-20 Du Pont Apparatus for codispensing a plurality of liquids
US3325056A (en) * 1966-02-23 1967-06-13 Du Pont Apparatus for codispensing a plurality of liquids
US3338479A (en) * 1966-04-04 1967-08-29 Leonard L Marraffino Mixing head with secondary fluid adapted for connection with discharge means of primary fluid container
FR2024210A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1968-11-25 1970-08-28 Gillette Co
US3594476A (en) * 1969-05-12 1971-07-20 Massachusetts Inst Technology Submicron aqueous aerosols containing lecithin
GB1302671A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1970-08-29 1973-01-10
FR2122149A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1971-01-16 1972-08-25 Wilkinson Sword Ltd
DE2346730A1 (de) * 1973-09-17 1975-04-17 Heyer Gmbh Carl Geraet zur herstellung eines programmierten therapeutischen aerosolregimes
DE2818655A1 (de) * 1977-05-10 1978-11-23 Ici Ltd Liposome
GB2001334A (en) * 1977-07-19 1979-01-31 Fisons Ltd Pressurised aerosol formulation
GB2013609A (en) * 1978-02-02 1979-08-15 Oreal Storage stability of aqueous dispersions of spherules
WO1981003318A1 (en) * 1980-05-12 1981-11-26 Polyfill Ag Pressurized tank
EP0087814A1 (de) * 1982-03-01 1983-09-07 Perfect-Valois Ventil GmbH Abgabeventil für Aerosoldosen
EP0100964A2 (de) * 1982-07-31 1984-02-22 Reifenrath, Rainer, Dr. Pharmazeutisches Erzeugnis zur Behandlung und Prophylaxe von Infektionen sowie von Husten und obstruktiven Atemwegserkrankungen sowie Verfahren zu seiner Herstellung
GB2136762A (en) * 1983-03-22 1984-09-26 Oreal Process for preparing lipid vesicles by vaporisation of solvents
EP0137897A1 (de) * 1983-08-16 1985-04-24 Sterwin Ag. Zweikomponentenpackung

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Title
NATURE, vol. 288, no. 5791, 11 décembre 1980, pages 602-604, Chesham, GB; L.D. LESERMAN et al.: "Targeting to cells of fluorescent liposomes covalently coupled with monoclonal antibody or protein A" *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158441A3 (en) * 1984-03-08 1986-05-21 Phares Pharmaceutical Research N.V. Liposome-forming composition
EP0190926A3 (en) * 1985-02-05 1987-09-02 Sterwin Ag. A method for the preparation of liposomes, a pack for use therein and a composition for use in preparing a liposomal material
WO1987001586A1 (en) * 1985-09-17 1987-03-26 Biocompatibles Limited Aerosol
EP0221821A3 (en) * 1985-11-01 1988-01-27 Centre National De La Recherche Scientifique (Cnrs) New aerosol composition for in vivo imaging and therapy
FR2638639A1 (fr) * 1988-11-08 1990-05-11 Parincos Parfumerie Cosmet Int Composition et procede d'obtention de liposomes oligolamellaires en vue d'une application en cosmetologie et dermatologie topique
EP0616801A1 (de) * 1993-03-24 1994-09-28 Ciba-Geigy Ag Verfahren zur Herstellung einer Liposomendispersion im Hochdruckbereich
WO1995031172A1 (en) * 1994-05-16 1995-11-23 Phares Pharmaceutical Holland B.V. Liposome forming compositions
ES2111488A1 (es) * 1996-01-17 1998-03-01 Lucas Meyer S A Utilizacion de composiciones proliposomas en la tintura, blanqueo y suavizado de la industrial textil y procedimiento para la preparacion de ba¦os de tintura a partir de dichas composiciones proliposomas.
WO2007049278A3 (en) * 2005-10-26 2007-09-13 Yissum Res Dev Co A method for preparing liposomes and uses thereof

Also Published As

Publication number Publication date
CH667384B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-10-14
SE8404118L (sv) 1985-02-18
JPS6089414A (ja) 1985-05-20
IE57537B1 (en) 1993-02-24
IT8422357A0 (it) 1984-08-17
AU3178684A (en) 1985-02-21
LU85512A1 (fr) 1985-04-24
DK163479C (da) 1992-08-03
KR850001689A (ko) 1985-04-01
ATA263684A (de) 1989-08-15
FI85214B (fi) 1991-12-13
PT79104B (en) 1986-09-08
FR2550706B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-09-23
DK392884D0 (da) 1984-08-16
ZA846064B (en) 1985-03-27
FI843223A7 (fi) 1985-02-18
NZ209112A (en) 1988-06-30
SE8404118D0 (sv) 1984-08-16
DK163479B (da) 1992-03-09
AU569314B2 (en) 1988-01-28
ES535163A0 (es) 1985-08-01
FI843223A0 (fi) 1984-08-15
IL72590A (en) 1987-12-31
NL8402514A (nl) 1985-03-18
FI85214C (fi) 1992-03-25
AT389993B (de) 1990-02-26
GB2145107A (en) 1985-03-20
IT1175612B (it) 1987-07-15
SE459471B (sv) 1989-07-10
ES8506445A1 (es) 1985-08-01
IE842121L (en) 1985-02-17
GB2145107B (en) 1987-02-18
GB8420850D0 (en) 1984-09-19
PT79104A (en) 1984-09-01
GB8322178D0 (en) 1983-09-21
BE900375A (fr) 1985-02-18
IL72590A0 (en) 1984-11-30
GR80127B (en) 1984-12-14
DK392884A (da) 1985-02-18
DE3430385A1 (de) 1985-03-07

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