FR2499574A1 - Nouveaux derives de la furo-(3,4-c)-pyridine et leur preparation - Google Patents
Nouveaux derives de la furo-(3,4-c)-pyridine et leur preparation Download PDFInfo
- Publication number
- FR2499574A1 FR2499574A1 FR8202137A FR8202137A FR2499574A1 FR 2499574 A1 FR2499574 A1 FR 2499574A1 FR 8202137 A FR8202137 A FR 8202137A FR 8202137 A FR8202137 A FR 8202137A FR 2499574 A1 FR2499574 A1 FR 2499574A1
- Authority
- FR
- France
- Prior art keywords
- radical
- carbon atoms
- compound
- furo
- isopropylidene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8104072 | 1981-02-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2499574A1 true FR2499574A1 (fr) | 1982-08-13 |
FR2499574B1 FR2499574B1 (en18) | 1984-03-30 |
Family
ID=10519587
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8202137A Granted FR2499574A1 (fr) | 1981-02-10 | 1982-02-10 | Nouveaux derives de la furo-(3,4-c)-pyridine et leur preparation |
FR8202136A Granted FR2499406A1 (fr) | 1981-02-10 | 1982-02-10 | Medicaments a base de nouveaux derives de la furo-(3,4-c)-pyridine |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8202136A Granted FR2499406A1 (fr) | 1981-02-10 | 1982-02-10 | Medicaments a base de nouveaux derives de la furo-(3,4-c)-pyridine |
Country Status (34)
Country | Link |
---|---|
US (1) | US4383998A (en18) |
JP (1) | JPS57150688A (en18) |
KR (1) | KR870000206B1 (en18) |
AR (1) | AR230284A1 (en18) |
AU (1) | AU545876B2 (en18) |
BE (1) | BE891797A (en18) |
CA (1) | CA1175837A (en18) |
CH (1) | CH649554A5 (en18) |
DE (1) | DE3204596A1 (en18) |
DK (1) | DK157551C (en18) |
DZ (1) | DZ376A1 (en18) |
ES (1) | ES8302714A1 (en18) |
FI (1) | FI75347C (en18) |
FR (2) | FR2499574A1 (en18) |
GB (1) | GB2092586B (en18) |
GR (1) | GR75905B (en18) |
HK (1) | HK22485A (en18) |
HU (1) | HU185088B (en18) |
IE (1) | IE52376B1 (en18) |
IL (1) | IL64759A (en18) |
IN (1) | IN156817B (en18) |
IT (1) | IT1157252B (en18) |
LU (1) | LU83886A1 (en18) |
MA (1) | MA19378A1 (en18) |
MX (1) | MX6983E (en18) |
NL (1) | NL186697C (en18) |
NO (1) | NO156373C (en18) |
NZ (1) | NZ199528A (en18) |
OA (1) | OA07003A (en18) |
PT (1) | PT74408B (en18) |
SE (1) | SE456994B (en18) |
SG (1) | SG85384G (en18) |
YU (1) | YU44000B (en18) |
ZA (1) | ZA82158B (en18) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2559152A1 (fr) * | 1984-02-02 | 1985-08-09 | Scras | Nouveaux derives de la furo-(3,4-c)-pyridine substitues en position 6, ainsi que leur procede de preparation |
DE3990349T1 (de) * | 1988-04-06 | 1990-04-26 | Scras | Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4735950A (en) * | 1983-04-05 | 1988-04-05 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) | Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same |
IN160104B (en18) * | 1983-04-05 | 1987-06-27 | Scras | |
GB8327817D0 (en) * | 1983-10-18 | 1983-11-16 | Scras | 4-halo-furo-(3 4-c)-pyridine derivatives |
GB8330517D0 (en) * | 1983-11-16 | 1983-12-21 | Scras | 6-vinyl-furo-(3,4-c)pyridine derivatives |
GB8330658D0 (en) * | 1983-11-17 | 1983-12-29 | Scras | 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives |
GB8414559D0 (en) * | 1984-06-07 | 1984-07-11 | Scras | Pyridine derivatives |
GB8422379D0 (en) * | 1984-09-05 | 1984-10-10 | Scras | Derivatives |
GB8427218D0 (en) * | 1984-10-27 | 1984-12-05 | Scras | Pyridine derivatives |
DE3519693A1 (de) * | 1985-06-01 | 1987-01-02 | Basf Ag | Pyridin-derivate, ihre herstellung und verwendung |
GB8808001D0 (en) * | 1988-04-06 | 1988-05-05 | Scras | Stereospecific preparative process for furol(3,4-c)pyridine derivatives |
GB8907480D0 (en) * | 1989-04-03 | 1989-05-17 | Scaras Societe De Conseils De | Separation of insomers of furo(3,4-c)pyridine derivatives |
GB8917168D0 (en) * | 1989-07-27 | 1989-09-13 | Scras | Asymmetric synthesis of furo(3,4-c)pyridine derivatives |
US5130252A (en) * | 1990-05-14 | 1992-07-14 | Synthetech, Inc. | Resolution of furopyridine enantiomers and synthetic precursors thereof |
GB0221494D0 (en) * | 2002-09-16 | 2002-10-23 | Generics Uk Ltd | Novel processes for the preparation of 1.3-dihydro-6-methylfuro (3,4-c) pyndin derivatives |
HUP0300990A2 (hu) * | 2003-04-15 | 2005-05-30 | SynoSens Kutató és Fejlesztő Kft. | Szinergista gyógyszer-kombináció a diabetesz megelőzésére vagy kezelésére |
US20060089374A1 (en) * | 2003-07-17 | 2006-04-27 | Glenn Cornett | Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease |
US20050043391A1 (en) * | 2003-07-17 | 2005-02-24 | Fong Benson M. | Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome |
WO2006034510A2 (en) * | 2004-09-22 | 2006-03-30 | Glenn Cornett | Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease |
US20060154959A1 (en) * | 2005-01-13 | 2006-07-13 | Navitas Pharma | Combination therapies of cicletanine and carvedilol |
US20060153934A1 (en) * | 2005-01-13 | 2006-07-13 | Navitas Pharma | Combination therapies of cicletanine and magnesium |
US20070141174A1 (en) * | 2005-01-13 | 2007-06-21 | Navitas Pharma, Inc. | Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension |
US20080096915A1 (en) * | 2005-01-13 | 2008-04-24 | Greenberg Traurig LLP | Compositions for the treatment of metabolic disorders |
US20070105817A1 (en) * | 2005-11-09 | 2007-05-10 | Jim Page | Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension |
WO2008085872A1 (en) * | 2007-01-03 | 2008-07-17 | Cornett Glenn V | Cicletanine and pkc inhibitors in the treatment of pulmonary and cardiac disorders |
AR073259A1 (es) * | 2008-07-29 | 2010-10-28 | Merck & Co Inc | Derivados de furosemida utiles como diureticos |
US8214941B2 (en) | 2008-10-02 | 2012-07-10 | Kohler Co. | Slip-fit clamping system for mounting a fitting on a wall |
EP2485734B1 (en) * | 2009-10-09 | 2014-07-02 | Merck Sharp & Dohme Corp. | Diuretics |
US8354394B2 (en) | 2009-10-29 | 2013-01-15 | Merck Sharp & Dohme Corp. | Diuretics |
WO2015103445A1 (en) * | 2013-12-31 | 2015-07-09 | Rockey Don C | Systems, methods, techniques, and compounds in research and treatment of portal hypertension and other conditions |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2409998A1 (fr) * | 1977-11-25 | 1979-06-22 | Scras | Nouveau derive de la pyridine et sa preparation |
-
1982
- 1982-01-06 IN IN11/DEL/82A patent/IN156817B/en unknown
- 1982-01-08 US US06/338,140 patent/US4383998A/en not_active Expired - Lifetime
- 1982-01-11 ZA ZA82158A patent/ZA82158B/xx unknown
- 1982-01-11 IL IL64759A patent/IL64759A/xx unknown
- 1982-01-12 GR GR66981A patent/GR75905B/el unknown
- 1982-01-15 BE BE0/207069A patent/BE891797A/fr not_active IP Right Cessation
- 1982-01-19 NL NLAANVRAGE8200180,A patent/NL186697C/xx not_active IP Right Cessation
- 1982-01-20 NZ NZ199528A patent/NZ199528A/en unknown
- 1982-01-21 AR AR288193A patent/AR230284A1/es active
- 1982-01-21 LU LU83886A patent/LU83886A1/fr unknown
- 1982-01-28 CH CH508/82A patent/CH649554A5/fr not_active IP Right Cessation
- 1982-01-28 OA OA57599A patent/OA07003A/xx unknown
- 1982-01-28 NO NO820253A patent/NO156373C/no not_active IP Right Cessation
- 1982-02-01 MA MA19583A patent/MA19378A1/fr unknown
- 1982-02-04 FI FI820353A patent/FI75347C/fi not_active IP Right Cessation
- 1982-02-05 YU YU253/82A patent/YU44000B/xx unknown
- 1982-02-07 DZ DZ826443A patent/DZ376A1/fr active
- 1982-02-08 IT IT19502/82A patent/IT1157252B/it active
- 1982-02-08 GB GB8203522A patent/GB2092586B/en not_active Expired
- 1982-02-09 KR KR8200536A patent/KR870000206B1/ko active
- 1982-02-09 CA CA000395857A patent/CA1175837A/en not_active Expired
- 1982-02-09 IE IE288/82A patent/IE52376B1/en not_active IP Right Cessation
- 1982-02-09 DK DK054382A patent/DK157551C/da not_active IP Right Cessation
- 1982-02-09 PT PT74408A patent/PT74408B/pt unknown
- 1982-02-09 ES ES509449A patent/ES8302714A1/es not_active Expired
- 1982-02-09 AU AU80294/82A patent/AU545876B2/en not_active Expired
- 1982-02-09 SE SE8200744A patent/SE456994B/sv not_active IP Right Cessation
- 1982-02-09 MX MX829909U patent/MX6983E/es unknown
- 1982-02-10 DE DE19823204596 patent/DE3204596A1/de active Granted
- 1982-02-10 FR FR8202137A patent/FR2499574A1/fr active Granted
- 1982-02-10 FR FR8202136A patent/FR2499406A1/fr active Granted
- 1982-02-10 HU HU82405A patent/HU185088B/hu unknown
- 1982-02-10 JP JP57019038A patent/JPS57150688A/ja active Granted
-
1984
- 1984-11-29 SG SG853/84A patent/SG85384G/en unknown
-
1985
- 1985-03-21 HK HK224/85A patent/HK22485A/xx not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2409998A1 (fr) * | 1977-11-25 | 1979-06-22 | Scras | Nouveau derive de la pyridine et sa preparation |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2559152A1 (fr) * | 1984-02-02 | 1985-08-09 | Scras | Nouveaux derives de la furo-(3,4-c)-pyridine substitues en position 6, ainsi que leur procede de preparation |
FR2559062A1 (fr) * | 1984-02-02 | 1985-08-09 | Scras | Medicaments a base de nouveaux derives 6-substitues de la furo-(3,4-c)-pyridine |
DE3990349T1 (de) * | 1988-04-06 | 1990-04-26 | Scras | Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen |
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