FR2479222B1 - - Google Patents

Info

Publication number
FR2479222B1
FR2479222B1 FR8106403A FR8106403A FR2479222B1 FR 2479222 B1 FR2479222 B1 FR 2479222B1 FR 8106403 A FR8106403 A FR 8106403A FR 8106403 A FR8106403 A FR 8106403A FR 2479222 B1 FR2479222 B1 FR 2479222B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8106403A
Other languages
French (fr)
Other versions
FR2479222A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12604367&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2479222(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of FR2479222A1 publication Critical patent/FR2479222A1/fr
Application granted granted Critical
Publication of FR2479222B1 publication Critical patent/FR2479222B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR8106403A 1980-03-31 1981-03-31 Derives de composes du type monacoline k ayant une activite inhibitrice sur la biosynthese du cholesterol, leur procede de preparation et leur application en therapeutique Granted FR2479222A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55041292A JPH0692381B2 (ja) 1980-03-31 1980-03-31 Ｍｂ−５３０ａ誘導体

Publications (2)

Publication Number Publication Date
FR2479222A1 FR2479222A1 (fr) 1981-10-02
FR2479222B1 true FR2479222B1 (ja) 1983-08-26

Family

ID=12604367

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8106403A Granted FR2479222A1 (fr) 1980-03-31 1981-03-31 Derives de composes du type monacoline k ayant une activite inhibitrice sur la biosynthese du cholesterol, leur procede de preparation et leur application en therapeutique

Country Status (15)

Country Link
JP (1) JPH0692381B2 (ja)
AT (1) ATA150781A (ja)
AU (1) AU6893281A (ja)
BE (1) BE888214A (ja)
CH (1) CH646966A5 (ja)
DE (2) DE3112566A1 (ja)
DK (3) DK151273C (ja)
FI (1) FI810991L (ja)
FR (1) FR2479222A1 (ja)
GB (1) GB2073193A (ja)
IE (1) IE52367B1 (ja)
IT (1) IT1144325B (ja)
MX (1) MX9203567A (ja)
NL (1) NL8101592A (ja)
SE (1) SE461590B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472426A (en) * 1982-12-22 1984-09-18 Merck & Co., Inc. Antihypercholesterolemic compounds
DE3682557D1 (de) * 1985-09-13 1992-01-02 Sankyo Co Hydroxy-ml-236b-derivate, deren herstellung und anwendung.
US4997848A (en) * 1987-10-27 1991-03-05 Sankyo Company, Limited Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
US5075327A (en) * 1988-08-10 1991-12-24 Hoffmann-La Roche Inc. Antipsoriatic agents
US5021451A (en) * 1988-11-14 1991-06-04 Hoffman-La Roche Inc. Method for inhibiting hyperproliferative diseases
US5200549A (en) * 1988-11-14 1993-04-06 Hoffman-La Roche Inc. Antipsoriatic agents
US5073568A (en) * 1988-11-14 1991-12-17 Hoffmann-La Roche Inc. Antipsoriatic agents
US5159104A (en) * 1991-05-01 1992-10-27 Merck & Co., Inc. Process to simvastatin ester
FR2937537A1 (fr) * 2008-10-29 2010-04-30 Centre Nat Rech Scient Nanoparticules de statine
KR101820099B1 (ko) 2013-01-18 2018-01-18 에스프린팅솔루션 주식회사 저항 발열체, 이를 채용한 가열 부재, 및 정착 장치
RU2020126177A (ru) 2018-01-09 2022-02-10 Лиганд Фармасьютикалз, Инк. Ацетальные соединения и их терапевтическое применение

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (ja) * 1974-06-07 1981-03-18
JPS5925599B2 (ja) * 1979-02-20 1984-06-19 三共株式会社 新生理活性物質モナコリンｋおよびその製造法
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
AU535944B2 (en) * 1979-06-15 1984-04-12 Merck & Co., Inc. Hypocholestermic fermentation products from aspergillus
PT72394B (en) * 1980-02-04 1982-09-06 Merck & Co Inc Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
US4282155A (en) * 1980-02-04 1981-08-04 Merck & Co., Inc. Antihypercholesterolemic compounds
AU548996B2 (en) * 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
ZA81703B (en) * 1980-02-04 1982-09-29 Merck & Co Inc New antihypercholesterolemic compounds,intermediates and processes

Also Published As

Publication number Publication date
AU6893281A (en) 1981-10-08
SE8102047L (sv) 1981-10-01
DK145481A (da) 1981-10-01
DE3112566A1 (de) 1982-03-11
IT1144325B (it) 1986-10-29
BE888214A (fr) 1981-09-30
ATA150781A (de) 1983-03-15
DK32290D0 (da) 1990-02-07
DK32290A (da) 1990-02-07
DK167805B1 (da) 1993-12-20
MX9203567A (es) 1992-09-01
DK32190D0 (da) 1990-02-07
GB2073193A (en) 1981-10-14
JPS56138181A (en) 1981-10-28
FR2479222A1 (fr) 1981-10-02
CH646966A5 (de) 1984-12-28
DK32190A (da) 1990-02-07
SE461590B (sv) 1990-03-05
DK151273C (da) 1988-07-04
IT8167438A0 (it) 1981-03-30
IE810698L (en) 1981-09-30
DE3153666C2 (de) 1993-11-11
DK151273B (da) 1987-11-16
FI810991L (fi) 1981-10-01
JPH0692381B2 (ja) 1994-11-16
DE3112566C2 (ja) 1990-04-05
NL8101592A (nl) 1981-10-16
IE52367B1 (en) 1987-09-30

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