FR2412541A1 - Procede pour la preparation de derives de la 7-hydroxycoumarine - Google Patents

Procede pour la preparation de derives de la 7-hydroxycoumarine

Info

Publication number
FR2412541A1
FR2412541A1 FR7830524A FR7830524A FR2412541A1 FR 2412541 A1 FR2412541 A1 FR 2412541A1 FR 7830524 A FR7830524 A FR 7830524A FR 7830524 A FR7830524 A FR 7830524A FR 2412541 A1 FR2412541 A1 FR 2412541A1
Authority
FR
France
Prior art keywords
hydroxycoumarine
preparation
derivatives
acid
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7830524A
Other languages
English (en)
French (fr)
Other versions
FR2412541B1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Publication of FR2412541A1 publication Critical patent/FR2412541A1/fr
Application granted granted Critical
Publication of FR2412541B1 publication Critical patent/FR2412541B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR7830524A 1977-11-17 1978-10-26 Procede pour la preparation de derives de la 7-hydroxycoumarine Granted FR2412541A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT29765/77A IT1088554B (it) 1977-11-17 1977-11-17 Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina

Publications (2)

Publication Number Publication Date
FR2412541A1 true FR2412541A1 (fr) 1979-07-20
FR2412541B1 FR2412541B1 (de) 1982-09-10

Family

ID=11228398

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7830524A Granted FR2412541A1 (fr) 1977-11-17 1978-10-26 Procede pour la preparation de derives de la 7-hydroxycoumarine
FR7903385A Granted FR2412542A1 (fr) 1977-11-17 1979-02-09 Procede pour la preparation de derives de la 7-hydroxycoumarine

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7903385A Granted FR2412542A1 (fr) 1977-11-17 1979-02-09 Procede pour la preparation de derives de la 7-hydroxycoumarine

Country Status (17)

Country Link
US (2) US4296039A (de)
JP (2) JPS5479282A (de)
AT (1) AT371815B (de)
BE (1) BE871315A (de)
CA (1) CA1100498A (de)
CH (1) CH635334A5 (de)
DE (1) DE2846083A1 (de)
ES (2) ES474445A1 (de)
FI (1) FI783470A (de)
FR (2) FR2412541A1 (de)
GB (1) GB2008109B (de)
GR (1) GR66562B (de)
IT (1) IT1088554B (de)
NL (1) NL7810946A (de)
PT (1) PT68788A (de)
YU (1) YU40537B (de)
ZA (1) ZA785739B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1088554B (it) * 1977-11-17 1985-06-10 F I D I A Spa Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina
IT1100069B (it) * 1978-11-06 1985-09-28 Fidia Spa Procedimento selettivo per la preparazione di derivati della 7-idrossicumarina
IT1212882B (it) * 1983-07-29 1989-11-30 Della Valle Francesco Derivati basici della cumarina
IT1212907B (it) * 1983-12-21 1989-11-30 Romeo Aurelio Preparazione di fenoli alogenati
US4788298A (en) * 1985-01-22 1988-11-29 Eastman Kodak Company Process for the preparation of coumarin compounds
US4650881A (en) * 1985-04-01 1987-03-17 Iowa State University Research Foundation, Inc. Synthesis of isocoumarins via thallation-olefination of arenes
US4647666A (en) * 1985-04-01 1987-03-03 Iowa State University Research Foundation, Inc. Heterocyclic synthesis via thallation and subsequent palladium-promoted olefination
US4882412A (en) * 1987-11-30 1989-11-21 Eastman Kodak Company Polyester polymer containing the residue of the UV absorbing benzopyran compound and shaped articles produced therefrom
US5356929A (en) * 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
WO1990008529A2 (en) * 1989-01-23 1990-08-09 Lehigh University 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor
US5516629A (en) * 1990-04-16 1996-05-14 Cryopharm Corporation Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
IT1247476B (it) * 1991-06-14 1994-12-17 Fidia Spa Derivati della cumarina.
IT1265665B1 (it) * 1993-06-21 1996-11-22 Fidia Spa Composizioni farmaceutiche comprendenti 8-cloro-3-(beta- dietilaminoetil)-4-metil-7-etossicarbonilmetossi cumarina base e
WO1997036581A1 (en) * 1996-03-29 1997-10-09 Therakos, Inc. Photopheresis treatment of leukocytes
CN1215305A (zh) 1996-04-09 1999-04-28 特拉科斯有限公司 从生物液中去除补骨脂素的方法
US6265421B1 (en) 1997-06-25 2001-07-24 Orion Corporation Phospholamban inhibitors and a method for increasing coronary flow
HUP0004089A2 (hu) * 1997-07-10 2001-04-28 Therakos, Inc. A bél és a húgyhólyag gyulladásos rendellenességeinek kezelése testen kívüli fotoferezissel
US6627233B1 (en) * 1997-09-18 2003-09-30 Wm. Wrigley Jr. Company Chewing gum containing physiological cooling agents
US6538022B1 (en) 1997-09-24 2003-03-25 Orion Corporation Compounds for deactivating phospholamban function on Ca-ATPase (phopholamban inhibitors)
US5968959A (en) * 1997-12-12 1999-10-19 Orion Corporation Method for the prevention and treatment of stunned myocardium
ES2211123T3 (es) * 1998-07-16 2004-07-01 Gentest Corporation Reactivos para el ensayo fluorescente cyp2d.
US6219584B1 (en) 1999-07-09 2001-04-17 Therakos, Inc. Method and system for determining an effective amount of light energy to delivery to fluids having targets for the light energy
US6495366B1 (en) 1999-09-03 2002-12-17 Therakos, Inc. Uninterrupted flow pump apparatus and method
US8722422B2 (en) 1999-09-03 2014-05-13 Therakos, Inc. Uninterrupted flow pump apparatus and method
US6207404B1 (en) 1999-09-30 2001-03-27 Gentest Corporation Coumarin-based CYP3A fluorescent assay reagents
US6793643B1 (en) 2000-04-21 2004-09-21 Therakos, Inc. Low extracorporeal volume treatment system
ATE502635T1 (de) 2002-08-19 2011-04-15 Pfizer Kombinationstherapie gegen hyperproliferative erkrankungen
US20050054586A1 (en) * 2003-06-30 2005-03-10 Bartels Stephen P. Treatment of ophthalmic disorders
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
US20100029017A1 (en) * 2008-07-29 2010-02-04 Becton, Dickinson And Company Mono-chlorinated hydroxycoumarin conjugates
US8431416B2 (en) * 2009-04-01 2013-04-30 Becton, Dickinson And Company Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JP7128969B2 (ja) 2019-01-18 2022-08-31 アストラゼネカ・アクチエボラーグ Ｐｃｓｋ９阻害剤及びその使用方法
EP4230196A1 (de) 2022-02-21 2023-08-23 Som Innovation Biotech, S.A. Verbindungen zur verwendung bei der behandlung von dystrophinopathien

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361M (fr) * 1961-08-12 1964-02-24 Cassella Farbwerke Mainkur Ag Médicament coronaro-dilatateur renfermant un dérivé de la 7-hydroxy-coumarine.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1210883B (de) * 1961-11-09 1966-02-17 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Derivaten des 7-Oxycumarins
US3259635A (en) * 1962-07-26 1966-07-05 Cassella Farbwerke Mainkur Ag 7-hydroxy coumarin derivative
SE316484B (de) * 1964-07-17 1969-10-27 Cassella Farbwerke Mainkur Ag
AT276377B (de) * 1967-05-06 1969-11-25 Troponwerke Dinklage & Co Verfahren zur Herstellung neuer basischer Cumarinderivate und ihrer Salze
GB1146792A (en) * 1967-06-20 1969-03-26 Cassella Farbwerke Mainkur Ag 7-hydroxy-coumarin derivatives and process for their production
US3515721A (en) * 1967-06-26 1970-06-02 Cassella Farbwerke Mainkur Ag 3-tertiary-aminoethyl-4-methyl or phenyl-7-ethoxycarbonylmethoxy - halo or mononitro coumarins and congeners
DE2108185A1 (en) * 1971-02-20 1972-09-07 Troponwerke Dinklage & Co, 5000 Köln-Mülheim N-(3-aminoalkyl-2-oxo-2h-1-benzopyran-7-yl) ureas - as coronary vasodilators
DE2039867A1 (de) * 1970-08-11 1972-02-17 Troponwerke Dinklage & Co Pharmakologisch wirksame Coumarin-Drivate und Verfahren zu ihrer Darstellung
PL74614B1 (de) * 1971-07-19 1974-12-31
US3923836A (en) * 1973-07-18 1975-12-02 Smithkline Corp Chroman and chromene compounds
DE2543945A1 (de) * 1975-10-02 1977-04-21 Troponwerke Gmbh & Co Kg 2-benzopyranonderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2530405A1 (de) * 1975-07-08 1977-01-27 Troponwerke Dinklage & Co 2-benzopyranonderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IT1088554B (it) * 1977-11-17 1985-06-10 F I D I A Spa Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361M (fr) * 1961-08-12 1964-02-24 Cassella Farbwerke Mainkur Ag Médicament coronaro-dilatateur renfermant un dérivé de la 7-hydroxy-coumarine.

Also Published As

Publication number Publication date
US4296039A (en) 1981-10-20
ES480376A1 (es) 1980-04-01
GB2008109B (en) 1982-08-04
CH635334A5 (fr) 1983-03-31
FI783470A (fi) 1979-05-18
GB2008109A (en) 1979-05-31
IT1088554B (it) 1985-06-10
ZA785739B (en) 1979-09-26
AT371815B (de) 1983-08-10
JPS60243081A (ja) 1985-12-03
US4452811A (en) 1984-06-05
FR2412542B1 (de) 1983-02-25
YU261478A (en) 1983-01-21
DE2846083C2 (de) 1989-02-02
JPS5479282A (en) 1979-06-25
BE871315A (fr) 1979-02-15
ATA822078A (de) 1982-12-15
JPS6310154B2 (de) 1988-03-04
FR2412541B1 (de) 1982-09-10
FR2412542A1 (fr) 1979-07-20
YU40537B (en) 1986-02-28
GR66562B (de) 1981-03-27
ES474445A1 (es) 1980-01-16
DE2846083A1 (de) 1979-05-23
CA1100498A (en) 1981-05-05
NL7810946A (nl) 1979-05-21
PT68788A (en) 1978-12-01

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Legal Events

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ST Notification of lapse