PT68788A - Selected process for producing monohalogenated derivativesof 7-hydroxy-coumarin - Google Patents

Selected process for producing monohalogenated derivativesof 7-hydroxy-coumarin

Info

Publication number
PT68788A
PT68788A PT68788A PT6878878A PT68788A PT 68788 A PT68788 A PT 68788A PT 68788 A PT68788 A PT 68788A PT 6878878 A PT6878878 A PT 6878878A PT 68788 A PT68788 A PT 68788A
Authority
PT
Portugal
Prior art keywords
derivativesof
coumarin
hydroxy
selected process
monohalogenated
Prior art date
Application number
PT68788A
Other languages
English (en)
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Publication of PT68788A publication Critical patent/PT68788A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT68788A 1977-11-17 1978-11-15 Selected process for producing monohalogenated derivativesof 7-hydroxy-coumarin PT68788A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT29765/77A IT1088554B (it) 1977-11-17 1977-11-17 Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina

Publications (1)

Publication Number Publication Date
PT68788A true PT68788A (en) 1978-12-01

Family

ID=11228398

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68788A PT68788A (en) 1977-11-17 1978-11-15 Selected process for producing monohalogenated derivativesof 7-hydroxy-coumarin

Country Status (17)

Country Link
US (2) US4296039A (pt)
JP (2) JPS5479282A (pt)
AT (1) AT371815B (pt)
BE (1) BE871315A (pt)
CA (1) CA1100498A (pt)
CH (1) CH635334A5 (pt)
DE (1) DE2846083A1 (pt)
ES (2) ES474445A1 (pt)
FI (1) FI783470A (pt)
FR (2) FR2412541A1 (pt)
GB (1) GB2008109B (pt)
GR (1) GR66562B (pt)
IT (1) IT1088554B (pt)
NL (1) NL7810946A (pt)
PT (1) PT68788A (pt)
YU (1) YU40537B (pt)
ZA (1) ZA785739B (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1088554B (it) * 1977-11-17 1985-06-10 F I D I A Spa Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina
IT1100069B (it) * 1978-11-06 1985-09-28 Fidia Spa Procedimento selettivo per la preparazione di derivati della 7-idrossicumarina
IT1212882B (it) * 1983-07-29 1989-11-30 Della Valle Francesco Derivati basici della cumarina
IT1212907B (it) * 1983-12-21 1989-11-30 Romeo Aurelio Preparazione di fenoli alogenati
US4788298A (en) * 1985-01-22 1988-11-29 Eastman Kodak Company Process for the preparation of coumarin compounds
US4647666A (en) * 1985-04-01 1987-03-03 Iowa State University Research Foundation, Inc. Heterocyclic synthesis via thallation and subsequent palladium-promoted olefination
US4650881A (en) * 1985-04-01 1987-03-17 Iowa State University Research Foundation, Inc. Synthesis of isocoumarins via thallation-olefination of arenes
US4882412A (en) * 1987-11-30 1989-11-21 Eastman Kodak Company Polyester polymer containing the residue of the UV absorbing benzopyran compound and shaped articles produced therefrom
US5356929A (en) * 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
WO1990008529A2 (en) * 1989-01-23 1990-08-09 Lehigh University 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US5516629A (en) * 1990-04-16 1996-05-14 Cryopharm Corporation Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
IT1247476B (it) * 1991-06-14 1994-12-17 Fidia Spa Derivati della cumarina.
IT1265665B1 (it) * 1993-06-21 1996-11-22 Fidia Spa Composizioni farmaceutiche comprendenti 8-cloro-3-(beta- dietilaminoetil)-4-metil-7-etossicarbonilmetossi cumarina base e
CA2250919C (en) * 1996-03-29 2008-05-13 Therakos, Inc. Photopheresis treatment of leukocytes
WO1997037536A1 (en) 1996-04-09 1997-10-16 Therakos, Inc. Method for removal of psoralens from biological fluids
US6265421B1 (en) 1997-06-25 2001-07-24 Orion Corporation Phospholamban inhibitors and a method for increasing coronary flow
HUP0004089A2 (hu) * 1997-07-10 2001-04-28 Therakos, Inc. A bél és a húgyhólyag gyulladásos rendellenességeinek kezelése testen kívüli fotoferezissel
US6627233B1 (en) * 1997-09-18 2003-09-30 Wm. Wrigley Jr. Company Chewing gum containing physiological cooling agents
US6538022B1 (en) 1997-09-24 2003-03-25 Orion Corporation Compounds for deactivating phospholamban function on Ca-ATPase (phopholamban inhibitors)
US5968959A (en) * 1997-12-12 1999-10-19 Orion Corporation Method for the prevention and treatment of stunned myocardium
WO2000004008A1 (en) * 1998-07-16 2000-01-27 Gentest Corporation Novel cyp2d fluorescent assay reagents
US6219584B1 (en) 1999-07-09 2001-04-17 Therakos, Inc. Method and system for determining an effective amount of light energy to delivery to fluids having targets for the light energy
US8722422B2 (en) 1999-09-03 2014-05-13 Therakos, Inc. Uninterrupted flow pump apparatus and method
US6495366B1 (en) 1999-09-03 2002-12-17 Therakos, Inc. Uninterrupted flow pump apparatus and method
US6207404B1 (en) 1999-09-30 2001-03-27 Gentest Corporation Coumarin-based CYP3A fluorescent assay reagents
US6793643B1 (en) 2000-04-21 2004-09-21 Therakos, Inc. Low extracorporeal volume treatment system
CA2495962A1 (en) 2002-08-19 2004-03-04 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
US20050054586A1 (en) * 2003-06-30 2005-03-10 Bartels Stephen P. Treatment of ophthalmic disorders
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
EP2094643B1 (en) 2006-12-01 2012-02-29 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US20100029017A1 (en) * 2008-07-29 2010-02-04 Becton, Dickinson And Company Mono-chlorinated hydroxycoumarin conjugates
US8431416B2 (en) * 2009-04-01 2013-04-30 Becton, Dickinson And Company Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates
WO2014170786A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof
EP4230196A1 (en) 2022-02-21 2023-08-23 Som Innovation Biotech, S.A. Compounds for use in the treatment of dystrophinopathies

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1210883B (de) * 1961-11-09 1966-02-17 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Derivaten des 7-Oxycumarins
FR2361M (fr) * 1961-08-12 1964-02-24 Cassella Farbwerke Mainkur Ag Médicament coronaro-dilatateur renfermant un dérivé de la 7-hydroxy-coumarine.
US3259635A (en) * 1962-07-26 1966-07-05 Cassella Farbwerke Mainkur Ag 7-hydroxy coumarin derivative
SE316484B (pt) * 1964-07-17 1969-10-27 Cassella Farbwerke Mainkur Ag
AT276377B (de) * 1967-05-06 1969-11-25 Troponwerke Dinklage & Co Verfahren zur Herstellung neuer basischer Cumarinderivate und ihrer Salze
GB1146792A (en) * 1967-06-20 1969-03-26 Cassella Farbwerke Mainkur Ag 7-hydroxy-coumarin derivatives and process for their production
US3515721A (en) * 1967-06-26 1970-06-02 Cassella Farbwerke Mainkur Ag 3-tertiary-aminoethyl-4-methyl or phenyl-7-ethoxycarbonylmethoxy - halo or mononitro coumarins and congeners
DE2108185A1 (en) * 1971-02-20 1972-09-07 Troponwerke Dinklage & Co, 5000 Köln-Mülheim N-(3-aminoalkyl-2-oxo-2h-1-benzopyran-7-yl) ureas - as coronary vasodilators
DE2039867A1 (de) * 1970-08-11 1972-02-17 Troponwerke Dinklage & Co Pharmakologisch wirksame Coumarin-Drivate und Verfahren zu ihrer Darstellung
PL74614B1 (pt) * 1971-07-19 1974-12-31
US3923836A (en) * 1973-07-18 1975-12-02 Smithkline Corp Chroman and chromene compounds
DE2530405A1 (de) * 1975-07-08 1977-01-27 Troponwerke Dinklage & Co 2-benzopyranonderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2543945A1 (de) * 1975-10-02 1977-04-21 Troponwerke Gmbh & Co Kg 2-benzopyranonderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IT1088554B (it) * 1977-11-17 1985-06-10 F I D I A Spa Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina

Also Published As

Publication number Publication date
GB2008109A (en) 1979-05-31
FR2412542A1 (fr) 1979-07-20
CA1100498A (en) 1981-05-05
ES474445A1 (es) 1980-01-16
FR2412541B1 (pt) 1982-09-10
GR66562B (pt) 1981-03-27
DE2846083A1 (de) 1979-05-23
JPS6310154B2 (pt) 1988-03-04
JPS5479282A (en) 1979-06-25
FR2412541A1 (fr) 1979-07-20
ZA785739B (en) 1979-09-26
AT371815B (de) 1983-08-10
JPS60243081A (ja) 1985-12-03
US4296039A (en) 1981-10-20
FI783470A (fi) 1979-05-18
CH635334A5 (fr) 1983-03-31
NL7810946A (nl) 1979-05-21
YU261478A (en) 1983-01-21
IT1088554B (it) 1985-06-10
DE2846083C2 (pt) 1989-02-02
GB2008109B (en) 1982-08-04
US4452811A (en) 1984-06-05
ATA822078A (de) 1982-12-15
FR2412542B1 (pt) 1983-02-25
YU40537B (en) 1986-02-28
BE871315A (fr) 1979-02-15
ES480376A1 (es) 1980-04-01

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